Dihydromundulone

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 异黄酮类化合物
• 英文名称: Dihydromundulone
• 英文别名: 3-hydroxy-7-(5-methoxy-2,2-dimethyl-3,4-dihydrochromen-6-yl)-2,2-dimethyl-3,4,7,8-tetrahydropyrano[3,2-g]chromen-6-one
• 化学式: C₂₆H₃₀O₆
• 分子量: 438.5
• InChiKey: NMWLIIRACAPWHT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  32
• 可旋转键数：
  2
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  74.2
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• COMPOSITIONS AND METHODS FOR INHIBITING HEDGEHOG PATHWAY
  申请人：Shrivastava Shivani

  公开号：US20220233539A1

  公开（公告）日：2022-07-28

  The present invention relates to the use of compositions and methods for treating or preventing a cancer condition in a subject. The use of composition comprises methods of treating or preventing cancer with agents that inhibit Hedgehog pathway activity. The pharmaceutical composition will further comprise agents that inhibit Smoothened receptor and/or Gli transcription in a subject.