5,7,2'-三羟基-4'-甲氧基异黄酮 | 32884-35-8

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 异黄酮类化合物
• 中文名称: 5,7,2'-三羟基-4'-甲氧基异黄酮
• 英文名称: 2'-hydroxybiochanin A
• 英文别名: 5,7,2'-trihydroxy-4'-methoxyisoflavone；dehydroferreirin；2',5,7-trihydroxy-4'-methoxyisoflavone；5,7-dihydroxy-3-(2-hydroxy-4-methoxyphenyl)chromen-4-one
• CAS: 32884-35-8
• 化学式: C₁₆H₁₂O₆
• 分子量: 300.268
• InChiKey: OZEVXMDBOINMTC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  22
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  96.2
• 氢给体数：
  3
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  kaempferide-7-O-β-D-glucoside 在 盐酸 、 水 作用下， 以 1,4-二氧六环 为溶剂， 反应 2.0h， 以3.6 mg的产率得到5,7,2'-三羟基-4'-甲氧基异黄酮
  参考文献：
  名称：

  Flavonoids fromLupinus texensisand their free radical scavenging activity

  摘要：

  Seventeen flavonoids including one new compound were isolated from Texas bluebonnet (Lupinus texensis), the state flower of Texas. Their structures were determined by extensive nuclear magnetic resonance and high-resolution electrospray ionization mass spectrometry analyses. High-performance liquid chromatography analytic method for simultaneous determination of the 17 compounds was established and validated. Eleven isolated flavonoids were first evaluated for their free radical scavenging activity using alpha,alpha-diphenyl-beta-picrylhydrazyl scavenging assay and they showed activity with EC50 48.6-172.5 mu g mL-1

  DOI：

  10.1080/14786419.2010.523423