7-Hydroxy-3-(4-hydroxyphenyl)-8-methoxy-4H-1-benzopyran-4-one | 915410-17-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 异黄酮类化合物
• 英文名称: 7-Hydroxy-3-(4-hydroxyphenyl)-8-methoxy-4H-1-benzopyran-4-one
• 英文别名: 7-hydroxy-3-(4-hydroxyphenyl)-8-methoxychromen-4-one
• CAS: 915410-17-2
• 化学式: C₁₆H₁₂O₅
• 分子量: 284.26
• InChiKey: UBLJWIMJOYYSCU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  76
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• METHOD OF MANUFACTURING METHOXY-ISOFLAVONES BY BIOTRANSFORMATION AND USE THEREOF
  申请人：NATIONAL UNIVERSITY OF TAINAN

  公开号：US20170198318A1

  公开（公告）日：2017-07-13

  A method of manufacturing methoxy-isoflavones by biotransformation and a use thereof are revealed herein. The method comprises the steps of synthesizing a nucleic acid sequence including a SpOMT2884 gene ofStreptomyces peucetius ; cloning the nucleic acid sequence into an expression vector to form a cyclic recombinant plasmid; transforming the cyclic recombinant plasmid into a microbial expression system ( Escherichia coli ); and incubating the microbial expression system in a medium containing 8-hydroxydaidzeins therein for generating methoxy-isoflavones.