4-Hydroxymedicarpin | 53950-54-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 异黄酮类化合物
• 英文名称: 4-Hydroxymedicarpin
• 英文别名: 9-methoxy-6a,11a-dihydro-6H-[1]benzofuro[3,2-c]chromene-3,4-diol
• CAS: 53950-54-2
• 化学式: C₁₆H₁₄O₅
• 分子量: 286.28
• InChiKey: YRFDJOAWSXSLMG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  21
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  68.2
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• Bioactive fractions and compounds from Dalbergia sissoo for the prevention or treatment of osteo-health related disorders
  申请人：Maurya Rakesh

  公开号：US10292994B2

  公开（公告）日：2019-05-21

  The present invention relates to bioactive fractions and compounds from Dalbergia sissoo for the prevention or treatment of osteo-health related disorders. The present invention relates in the field of pharmaceutical composition that provides new plant extracts, their fractions and pure compound isolated from natural sources that are useful for the prevention and/or treatment of various medical indications associated with estrogen dependent or independent diseases or syndromes or disorders preferably in the prevention or treatment of estrogen dependent or independent diseases or syndromes or disorders caused in humans and animals, and achievement of peak bone mass during skeletal growth and health in humans and animals. Particularly the present invention further relates to the processes for the preparation of biologically active extracts, fractions, and isolation of pure compounds, from Dalbergia sissoo plant from the family Fabaceae their pharmaceutically acceptable salts and compositions of the principal aspect of the present invention.

  本发明涉及用于预防或治疗骨健康相关疾病的 Dalbergia sissoo 的生物活性馏分和化合物。本发明涉及药物组合物领域，提供了新的植物提取物、其馏分和从天然来源分离的纯化合物，这些提取物、馏分和纯化合物可用于预防和/或治疗与雌激素依赖性或独立疾病或综合症或紊乱有关的各种医学指征，优选用于预防或治疗人类和动物引起的雌激素依赖性或独立疾病或综合症或紊乱，以及在人类和动物骨骼生长和健康过程中达到峰值骨量。特别是本发明进一步涉及从豆科植物Dalbergia sissoo中制备生物活性提取物、馏分和分离纯化合物的工艺，它们是本发明主要方面的药学上可接受的盐和组合物。
• BIOACTIVE FRACTIONS AND COMPOUNDS FROM DALBERGIA SISSOO FOR THE PREVENTION OR TREATMENT OF OSTEO-HEALTH RELATED DISORDERS
  申请人：Council of Scientific and Industrial Research

  公开号：EP2705047A1

  公开（公告）日：2014-03-12
• [EN] BIOACTIVE FRACTIONS AND COMPOUNDS FROM DALBERGIA SISSOO FOR THE PREVENTION OR TREATMENT OF OSTEO-HEALTH RELATED DISORDERS<br/>[FR] FRACTIONS ET COMPOSÉS BIOACTIFS ISSUS DE DALBERGIA SISSOO POUR PRÉVENIR OU TRAITER LES TROUBLES D'ORIGINE OSTÉOPATHIQUE
  申请人：COUNCIL SCIENT IND RES

  公开号：WO2012147102A1

  公开（公告）日：2012-11-01

  The present invention relates to bioactive fractions and compounds from Dalbergia sissoo for the prevention or treatment of osteo-health related disorders. The present invention relates in the field of pharmaceutical composition that provides new plant extracts, their fractions and pure compound isolated from natural sources that are useful for the prevention and/or treatment of various medical indications^ associated with estrogen dependent or independent diseases or syndromes or disorders preferably in the prevention or treatment of estrogen dependent or independent diseases or syndromes or disorders caused in humans and animals, and achievement of peak bone mass during skeletal growth and health in humans and animals. Particularly the present invention further relates to the processes for the preparation of biologically active extracts, fractions, and isolation of pure compounds, from Dalbergia sissoo plant from the family Fabaceae their pharmaceutically acceptable salts and compositions of the principal aspect of the present invention.