4-(1-Methoxycyclohexyl)oxycyclohex-2-en-1-one | 1026935-73-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4-(1-Methoxycyclohexyl)oxycyclohex-2-en-1-one
• CAS: 1026935-73-8
• 化学式: C₁₃H₂₀O₃
• 分子量: 224.3
• InChiKey: UKYJLQSJYSCLFI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.77
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4-(1-Methoxycyclohexyl)oxycyclohex-2-en-1-one 在 叔丁基过氧化氢 、 silica gel 、 三氯化铁 、 苄基三甲基氢氧化铵 、 lithium diisopropyl amide 作用下， 以 四氢呋喃 、 苯 为溶剂， 生成
  参考文献：
  名称：

  Synthesis of a family of epoxyvinyltriflate stereotetrads from 4-hydroxycyclohex-2-en-1-one

  摘要：

  4-Hydroxy cylohex-2-en-1-one can be converted into a family of highly oxygenated cyclohexyl epoxyvinyltriflates by epoxidation, rearrangement, and epoxidation. Furthermore, double stereoselection via Jacobsen epoxidation enables synthesis of compounds such as 20a which were previously very difficult to prepare. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(99)00344-5
• 作为产物：
  描述：

  1-甲氧基-1,4-环己二烯 在 水 、 草酸 、 对甲苯磺酸 作用下， 以 甲醇 为溶剂， 反应 2.0h， 生成 4-(1-Methoxycyclohexyl)oxycyclohex-2-en-1-one
  参考文献：
  名称：

  Synthesis of a family of epoxyvinyltriflate stereotetrads from 4-hydroxycyclohex-2-en-1-one

  摘要：

  4-Hydroxy cylohex-2-en-1-one can be converted into a family of highly oxygenated cyclohexyl epoxyvinyltriflates by epoxidation, rearrangement, and epoxidation. Furthermore, double stereoselection via Jacobsen epoxidation enables synthesis of compounds such as 20a which were previously very difficult to prepare. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(99)00344-5

文献信息

• Synthesis of a family of epoxyvinyltriflate stereotetrads from 4-hydroxycyclohex-2-en-1-one
  作者：J.B. Evarts、P.L. Fuchs

  DOI：10.1016/s0040-4039(99)00344-5

  日期：1999.4

  4-Hydroxy cylohex-2-en-1-one can be converted into a family of highly oxygenated cyclohexyl epoxyvinyltriflates by epoxidation, rearrangement, and epoxidation. Furthermore, double stereoselection via Jacobsen epoxidation enables synthesis of compounds such as 20a which were previously very difficult to prepare. (C) 1999 Elsevier Science Ltd. All rights reserved.