3-fluoro-4-(6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yloxy)aniline | 1394166-11-0
中文名称
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中文别名
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英文名称
3-fluoro-4-(6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yloxy)aniline
英文别名
3-fluoro-4-(6-methoxy-7-(3-(1-pyrrolidinyl)propoxy)quinoline-4-oxy)aniline；3-Fluoro-4-[6-methoxy-7-[3-(1-pyrrolidyl)propyloxy]quinolin-4-oxy]aniline；3-fluoro-4-[6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinolin-4-yl]oxyaniline
CAS
1394166-11-0
化学式
C23H26FN3O3
mdl
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分子量
411.476
InChiKey
KBEYWOFPIRHLJE-UHFFFAOYSA-N
BEILSTEIN
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EINECS
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物化性质
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计算性质
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ADMET
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安全信息
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SDS
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制备方法与用途
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上下游信息
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文献信息
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表征谱图
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同类化合物
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相关功能分类
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相关结构分类
计算性质
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辛醇/水分配系数(LogP)：4
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重原子数：30
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可旋转键数：8
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环数：4.0
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sp3杂化的碳原子比例：0.35
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拓扑面积：69.8
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氢给体数：1
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氢受体数：7
上下游信息
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上游原料
中文名称 英文名称 CAS号 化学式 分子量 —— 4-(2-fluoro-4-nitrophenoxy)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinoline 1394166-10-9 C23H24FN3O5 441.459 4-(2-氟-4-硝基苯氧基)-6-甲氧基-7-(苄氧基)喹啉 7-benzyloxy-4-(2-fluoro-4-nitrophenoxy)-6-methoxyquinoline 479690-03-4 C23H17FN2O5 420.397 —— 6-(methoxy)-7-(3-(1-pyrrolidinyl)propoxy)-4(1H)-quinolinone 205448-56-2 C17H22N2O3 302.373 —— 4-chloro-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinoline 733724-68-0 C17H21ClN2O2 320.819 4-氯-6-甲氧基-7-(3-吗啉丙氧基)喹啉 4-chloro-6-methoxy-7-(3-morpholin-4-yl-propoxy)-quinoline 205448-32-4 C17H21ClN2O3 336.818 —— 7-(3-chloropropoxy)-6-methoxy-4(1H)-quinolinone 1428788-16-2 C13H14ClNO3 267.712 -
下游产品
中文名称 英文名称 CAS号 化学式 分子量 —— (E)-N1-(3-fluoro-4-(6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-N4-(benzylidene)semicarbazide 1428787-47-6 C31H32FN5O4 557.625 —— (E)-N1-(3-fluoro-4-(6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-N4-(4-fluorobenzylidene)semicarbazide 1449763-28-3 C31H31F2N5O4 575.615 —— (E)-N1-(3-fluoro-4-(6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-N4-(4-chlorobenzylidene)semicarbazide 1449763-29-4 C31H31ClFN5O4 592.07 —— N-(3-fluoro-4-(6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-4-phenylpyrimidine-2-carboxamide 1491142-34-7 C34H32FN5O4 593.658 —— N-(3-fluoro-4-(6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-4-phenylpicolinamide 1491142-02-9 C35H33FN4O4 592.67 —— N-(3-fluoro-4-(6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-4-(4-fluorophenyl)picolinamide 1491142-05-2 C35H32F2N4O4 610.66 —— N-(3-fluoro-4-(6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-4-p-tolylpicolinamide 1491142-03-0 C36H35FN4O4 606.697 —— N-(3-fluoro-4-(6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-4-(4-fluorophenyl)pyrimidine-2-carboxamide 1491142-36-9 C34H31F2N5O4 611.648 —— N-(3-fluoro-4-(6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-4-(4-methoxyphenyl)picolinamide 1491142-08-5 C36H35FN4O5 622.696 —— N-(3-fluoro-4-(6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-4-p-tolylpyrimidine-2-carboxamide 1491142-35-8 C35H34FN5O4 607.684 —— N-(3-fluoro-4-(6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-4-(4-(trifluoromethyl)phenyl)picolinamide 1491142-07-4 C36H32F4N4O4 660.668 —— N-(3-fluoro-4-(6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-4-o-tolylpicolinamide 1491142-04-1 C36H35FN4O4 606.697 —— N-(3-fluoro-4-(6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-4-(2-fluorophenyl)picolinamide 1491142-06-3 C35H32F2N4O4 610.66 —— N-(3-fluoro-4-(6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-4-(2,4-dimethoxyphenyl)picolinamide 1491142-09-6 C37H37FN4O6 652.722 —— 6-fluoro-N-(3-fluoro-4-(6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-2-(4-methoxyphenyl)quinoline-4-carboxamide —— C40H36F2N4O5 690.746 —— 2-(3,4-dichlorophenyl)-N-(3-fluoro-4-(6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yloxy)phenyl)quinoline-4-carboxamide —— C39H33Cl2FN4O4 711.62 —— N-(3-fluoro-4-((6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yl)oxy)phenyl)-4-methyl-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxamide 1620683-81-9 C35H34FN5O5 623.684 —— N-(3-fluoro-4-((6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yl)oxy)phenyl)-1-(4-methoxyphenyl)-4-methyl-6-oxo-1,6-dihydropyridazine-3-carboxamide 1620683-86-4 C36H36FN5O6 653.71 —— 1-(4-chlorophenyl)-N-(3-fluoro-4-((6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yl)oxy)phenyl)-4-methyl-6-oxo-1,6-dihydropyridazine-3-carboxamide 1620683-87-5 C35H33ClFN5O5 658.129 —— N-(3-fluoro-4-((6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yl)oxy)phenyl)-1-(3-fluorophenyl)-4-methyl-6-oxo-1,6-dihydropyridazine-3-carboxamide 1620683-85-3 C35H33F2N5O5 641.674 —— N-(3-fluoro-4-((6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinolin-4-yl)oxy)phenyl)-1-(4-fluorophenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide 1394165-59-3 C40H37F2N5O5 705.761 —— N-(3-fluoro-4-((6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yl)oxy)phenyl)-1-(2-fluorophenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide 1394165-64-0 C39H34F2N4O5 676.72 —— 1-(3,4-difluorophenyl)-N-(3-fluoro-4-((6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yl)oxy)phenyl)-4-methyl-6-oxo-1,6-dihydropyridazine-3-carboxamide 1620683-88-6 C35H32F3N5O5 659.665 —— N-(3-fluoro-4-((6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yl)oxy)phenyl)-4-oxo-3-phenyl-3,4-dihydrophthalazine-1-carboxamide 1616244-54-2 C38H34FN5O5 659.717 —— N-(3-fluoro-4-((6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yl)oxy)phenyl)-3-(4-fluorophenyl)-4-oxo-3,4-dihydrophthalazine-1-carboxamide 1616244-55-3 C38H33F2N5O5 677.707 —— N-(3-fluoro-4-((6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yl)oxy)phenyl)-4-methyl-6-oxo-1-(2-methylphenyl)-1,6-dihydropyridazine-3-carboxamide 1620683-82-0 C36H36FN5O5 637.711 —— N-(3-fluoro-4-((6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yl)oxy)phenyl)-3-(4-methoxy phenyl)-4-oxo-3,4-dihydrophthalazine-1-carboxamide 1616244-61-1 C39H36FN5O6 689.743 —— 3-(4-bromophenyl)-N-(3-fluoro-4-((6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yl)oxy)phenyl)-4-oxo-3,4-dihydrophthalazine-1-carboxamide 1616244-58-6 C38H33BrFN5O5 738.613 —— N-(3-fluoro-4-((6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yl)oxy)phenyl)-3-(3-fluorophenyl)-4-oxo-3,4-dihydrophthalazine-1-carboxamide 1616244-56-4 C38H33F2N5O5 677.707 —— N-(3-fluoro-4-((6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-yl)oxy)phenyl)-3-(4-nitrophenyl)-4-oxo-3,4-dihydrophthalazine-1-carboxamide 1616244-60-0 C38H33FN6O7 704.714