2,2,4,4,5,5,7,7,8,8,10,10-dodecafluoro-3,6,9,12-tetraoxatricos-22-en-1-ol | 1262192-51-7

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 卤代醇
• 英文名称: 2,2,4,4,5,5,7,7,8,8,10,10-dodecafluoro-3,6,9,12-tetraoxatricos-22-en-1-ol
• 英文别名: 2-[2-[2-(1,1-Difluoro-2-undec-10-enoxyethoxy)-1,1,2,2-tetrafluoroethoxy]-1,1,2,2-tetrafluoroethoxy]-2,2-difluoroethanol；2-[2-[2-(1,1-difluoro-2-undec-10-enoxyethoxy)-1,1,2,2-tetrafluoroethoxy]-1,1,2,2-tetrafluoroethoxy]-2,2-difluoroethanol
• CAS: 1262192-51-7
• 化学式: C₁₉H₂₆F₁₂O₅
• 分子量: 562.393
• InChiKey: WKWBAMQUPVUBKY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.1
• 重原子数：
  36
• 可旋转键数：
  21
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  57.2
• 氢给体数：
  1
• 氢受体数：
  17

反应信息

• 作为反应物：
  描述：

  2,2,4,4,5,5,7,7,8,8,10,10-dodecafluoro-3,6,9,12-tetraoxatricos-22-en-1-ol 在 偶氮二异丁腈 、 sodium methylate 、 sodium hydride 作用下， 以 四氢呋喃 、 1,4-二氧六环 、 甲醇 、 mineral oil 为溶剂， 反应 5.08h， 生成 11,11,13,13,14,14,16,16,17,17,19,19-dodecafluoro-32-mercapto-3,6,9,12,15,18,21-heptaoxadotriacontan-1-ol
  参考文献：
  名称：

  Gold Nanoparticles Coated with Semi-Fluorinated Oligo(ethylene glycol) Produce Sub-100 nm Nanoparticle Vesicles without Templates

  摘要：

  Gold nanoparticles (NPs) with diameters of 5, 10, and 20 nm coated with semifluorinated oligo(ethylene glycol) ligands were formed into sub-100 nm hollow NP assemblies (NP vesicles) in THF without the use of a template. The NP vesicles maintained their structure even after the solvent was changed from THF to other solvents such as butanol or CH2Cl2. NMR analyses indicated that the fluorinated ligands are bundled on the NPs and that the solvophobic feature of the fluorinated bundles is the driving force for NP assembly. The formed NP vesicles were surface-enhanced Raman scattering-active capsules.

  DOI：

  10.1021/ja302122w
• 作为产物：
  描述：

  10-十一烯-1-醇 在 三甲胺盐酸盐 、 potassium carbonate 、 三乙胺 作用下， 以 二氯甲烷 、 N,N-二甲基甲酰胺 为溶剂， 反应 14.0h， 生成 2,2,4,4,5,5,7,7,8,8,10,10-dodecafluoro-3,6,9,12-tetraoxatricos-22-en-1-ol
  参考文献：
  名称：

  Gold Nanoparticles Coated with Semi-Fluorinated Oligo(ethylene glycol) Produce Sub-100 nm Nanoparticle Vesicles without Templates

  摘要：

  Gold nanoparticles (NPs) with diameters of 5, 10, and 20 nm coated with semifluorinated oligo(ethylene glycol) ligands were formed into sub-100 nm hollow NP assemblies (NP vesicles) in THF without the use of a template. The NP vesicles maintained their structure even after the solvent was changed from THF to other solvents such as butanol or CH2Cl2. NMR analyses indicated that the fluorinated ligands are bundled on the NPs and that the solvophobic feature of the fluorinated bundles is the driving force for NP assembly. The formed NP vesicles were surface-enhanced Raman scattering-active capsules.

  DOI：

  10.1021/ja302122w

文献信息

• Self-lubricating nanoparticles: self-organization into 3D-superlattices during a fast drying process
  作者：Takashi Nishio、Kenichi Niikura、Yasutaka Matsuo、Kuniharu Ijiro

  DOI：10.1039/c0cc03538f

  日期：——

  Fluorinated tetraethylene glycol-stabilized Au nanoparticles (FTEG-AuNPs) were well-dispersed in general polar organic solvents, such as methanol (MeOH) and THF. The cast film of FTEG-AuNPs on a TEM grid and a glass substrate was found to form a highly ordered 3D-superlattice assembly, whereas tetraethylene glycol-stabilized AuNPs (TEG-AuNPs) provide an amorphous AuNP aggregation. These data indicate that the fluorine feature on the surface of the FTEG-AuNPs is critical for the nanostructured assembly.

  氟化四乙二醇稳定的金纳米粒子（FTEG-AuNPs）在一般极性有机溶剂中，如甲醇（MeOH）和四氢呋喃（THF），分散良好。在透射电子显微镜（TEM）网格和玻璃基底上浇铸的FTEG-AuNPs薄膜形成了高度有序的三维超晶格组装，而四乙二醇稳定的金纳米粒子（TEG-AuNPs）则形成了无定形的金纳米粒子聚集。这些数据表明，FTEG-AuNPs表面的氟特征对纳米结构的组装至关重要。
• PARTICLE AGGREGATE, MANUFACTURING METHOD FOR PARTICLE AGGREGATE, FLUORESCENCE ENHANCING ELEMENT, AND DEVICE USING PHOTOCHEMICAL REACTIONS
  申请人：National University Corporation Hokkaido University

  公开号：EP2679322A1

  公开（公告）日：2014-01-01

  Provided is a hollow particle aggregate formed by aggregating a plurality of self-organizable particles, wherein a metal core is modified by a surface modifier for a metal core comprising a first segment comprising an optionally branched fluorinated alkylene glycol group, an optionally branched fluorinated alkylene group, or an optionally branched fluorinated azaalkylene group; a second segment comprising at least one hydrophilic group and bonding to one of the ends of a main chain of the first segment; and a functional group that bonds directly or indirectly to the another end of the main chain of the first segment and is able to bond to the metal core.

  提供了一种通过聚集多个可自组织颗粒而形成的中空颗粒聚集体，其中金属芯由表面改性剂对金属芯进行改性，该表面改性剂包括第一段，该第一段包括任选支化的氟化亚烷基乙二醇基团、任选支化的氟化亚烷基基团或任选支化的氟化偶氮亚烷基基团；第二段，包括至少一个亲水基团，并与第一段主链的一端结合；以及一个官能团，直接或间接与第一段主链的另一端结合，并能与金属芯结合。
• Particle Aggregate, Manufacturing Method for Particle Aggregate, Fluorescence Enhancing Element, and Device Using Photochemical Reactions
  申请人：Ijiro Kuniharu

  公开号：US20140077132A1

  公开（公告）日：2014-03-20

  Provided is a hollow particle aggregate formed by aggregating a plurality of self-organizable particles, wherein a metal core is modified by a surface modifier for a metal core comprising a first segment comprising an optionally branched fluorinated alkylene glycol group, an optionally branched fluorinated alkylene group, or an optionally branched fluorinated azaalkylene group; a second segment comprising at least one hydrophilic group and bonding to one of the ends of a main chain of the first segment; and a functional group that bonds directly or indirectly to the another end of the main chain of the first segment and is able to bond to the metal core.
• US9447316B2
  申请人：——

  公开号：US9447316B2

  公开（公告）日：2016-09-20
• Gold Nanoparticles Coated with Semi-Fluorinated Oligo(ethylene glycol) Produce Sub-100 nm Nanoparticle Vesicles without Templates
  作者：Kenichi Niikura、Naoki Iyo、Takeshi Higuchi、Takashi Nishio、Hiroshi Jinnai、Naoki Fujitani、Kuniharu Ijiro

  DOI：10.1021/ja302122w

  日期：2012.5.9

  Gold nanoparticles (NPs) with diameters of 5, 10, and 20 nm coated with semifluorinated oligo(ethylene glycol) ligands were formed into sub-100 nm hollow NP assemblies (NP vesicles) in THF without the use of a template. The NP vesicles maintained their structure even after the solvent was changed from THF to other solvents such as butanol or CH2Cl2. NMR analyses indicated that the fluorinated ligands are bundled on the NPs and that the solvophobic feature of the fluorinated bundles is the driving force for NP assembly. The formed NP vesicles were surface-enhanced Raman scattering-active capsules.