N-[3-chloro-4-(2-oxo-2H-chromen-3-yl)phenyl]-2-thiophenecarboxamide

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 异黄酮类化合物
• 英文名称: N-[3-chloro-4-(2-oxo-2H-chromen-3-yl)phenyl]-2-thiophenecarboxamide
• 英文别名: N-[3-chloro-4-(2-oxochromen-3-yl)phenyl]thiophene-2-carboxamide
• 化学式: C₂₀H₁₂ClNO₃S
• 分子量: 381.8
• InChiKey: YUYPXLHBBNBXTF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  26
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  83.6
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• [EN] NOVEL EFFECTIVE ANTIVIRAL COMPOUNDS AND METHODS USING SAME<br/>[FR] NOUVEAUX COMPOSÉS ANTIVIRAUX EFFICACES ET LEURS MÉTHODES D'UTILISATION
  申请人：UNIV PENNSYLVANIA

  公开号：WO2015187827A1

  公开（公告）日：2015-12-10

  The present invention includes compounds that are useful in preventing or treating viral infections caused by an enveloped RNA virus, such as viral infections caused by a filovirus, arenavirus, rhabdovirus, paramyxovirus, orthomyxovirus and/or retrovirus. The present invention further includes compositions comprising such compounds, and methods of treating a viral infection in a subject using such compounds.