6-Fluoro-4-methyl-3-phenylcoumarin | 288399-91-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 异黄酮类化合物
• 英文名称: 6-Fluoro-4-methyl-3-phenylcoumarin
• 英文别名: 6-fluoro-4-methyl-3-phenylchromen-2-one
• CAS: 288399-91-7
• 化学式: C₁₆H₁₁FO₂
• 分子量: 254.25
• InChiKey: YDMJHHMAJSWOMC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  19
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• USE OF COUMARIN DERIVATIVES IN ANTIFUNGAL THERAPY
  申请人：Stewart Colin

  公开号：US20100267653A1

  公开（公告）日：2010-10-21

  The invention provides coumarin compounds, in particular glycosidic coumarin compounds, useful in the treatment of dermatophyte fungal infections.
• Polypeptides and Their Use
  申请人：O'NEIL Deborah

  公开号：US20140155321A1

  公开（公告）日：2014-06-05

  The present invention relates to a polypeptide or a product comprising said polypeptide for use in the treatment and/or prevention of a fungal infection caused by Malassezia spp. and/or a Malassezia spp associated condition wherein the polypeptide comprises a sequence of about 25 to 200 amino acids wherein substantially all of the amino acids in said sequence are lysine; pharmaceutical compositions comprising said polypeptide or product and uses thereof.