7-(4-甲基-5-苯基-2H-1,2,3-三唑-2-基)-3-苯基-2-苯并吡喃酮 | 19683-09-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 异黄酮类化合物
• 中文名称: 7-(4-甲基-5-苯基-2H-1,2,3-三唑-2-基)-3-苯基-2-苯并吡喃酮
• 英文名称: 7-(4-methyl-5-phenyl-1,2,3-triazol-2-yl)-3-phenylcoumarin
• 英文别名: 7-<4-methyl-5-phenyl-2-(1,2,3-triazolyl)>-3-phenylcoumarin；2-<3-Phenyl-cumarinyl-(7)>-4-phenyl-5-methyl-v-triazol；7-(4-methyl-5-phenyl-[1,2,3]triazol-2-yl)-3-phenyl-chromen-2-one；7-(4-methyl-5-phenyl-2H-1,2,3-triazol-2-yl)-3-phenyl-2-benzopyrone；2H-1-Benzopyran-2-one, 7-(4-methyl-5-phenyl-2H-1,2,3-triazol-2-yl)-3-phenyl-；7-(4-methyl-5-phenyltriazol-2-yl)-3-phenylchromen-2-one
• CAS: 19683-09-1
• 化学式: C₂₄H₁₇N₃O₂
• 分子量: 379.418
• InChiKey: CLBWALOVEYKEEL-UHFFFAOYSA-N

物化性质

• 沸点：
  615.3±65.0 °C(Predicted)
• 密度：
  1.26±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  29
• 可旋转键数：
  3
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.04
• 拓扑面积：
  57
• 氢给体数：
  0
• 氢受体数：
  4

安全信息

• 海关编码：
  2934999090

文献信息

• Aryl-acrylic acid esters useful as precursors for organoleptic compounds
  申请人：Givaudan Roure (International) S.A.

  公开号：EP0936211A2

  公开（公告）日：1999-08-18

  The acrylic acid esters of formula I wherein A is a benzene or naphthalene ring, R1 is a saturated or unsaturated, straight or branched, alicyclic or aromatic C10-C30 hydrocarbon residue which can contain heteroatoms and can be substituted by an ionic substituent, R2 in 2- or 3-position is hydrogen, a straight or branched C1-C6 residue; an optionally substituted aromatic or optionally substituted heterocyclic residue, R3 and R4 stand for hydrogen, a straight or branched C1-C6 alkyl or C1-C6 alkoxy residue, a substituted or condensed heterocyclic residue, -OH, -NO2, -NH2, -N(C1-C6 alkyl)2, -N(hydroxyalkyl)2, -NHCO2CH3 or -NH(heterocycle), R2, R3 and R4 may be the same or different, X stands for -OH or NHR6, wherein R6 is hydrogen a saturated or unsaturated, straight or branched C1-C20 hydrocarbon or an optionally substituted aromatic or heterocyclic residue, and the acrylic double bond is of the E configuration, are useful for the delivery of organoleptic compounds, especially for flavours, fragrances and masking agents and antimicrobial compounds. They can also deliver fluorescent whitening agents.

  式 I 的丙烯酸酯 其中 A 是苯环或萘环、 R1 是饱和或不饱和、直链或支链、脂环或芳香的 C10-C30 烃残基，可含有杂原子并可被离子取代基取代、 2 位或 3 位的 R2 是氢、直链或支链 C1-C6 残基、任选取代的芳香族或任选取代的杂环残基、 R3 和 R4 代表氢、直链或支链 C1-C6 烷基或 C1-C6 烷氧基残基、取代或缩合杂环残基、-OH、-NO2、-NH2、-N（C1-C6 烷基）2、-N（羟基烷基）2、-NHCO2CH3 或-NH（杂环）、 R2、R3 和 R4 可以相同或不同、 X 代表-OH 或 NHR6，其中 R6 是氢，饱和或不饱和、直链或支链 C1-C20 烃，或任选取代的芳香族或杂环残基、 丙烯酸双键为 E 型构型、 可用于输送感官化合物，特别是香精、香料、掩蔽剂和抗菌化合物。它们还可以输送荧光增白剂。
• Paste-type dental cement
  申请人：GC Corporation

  公开号：EP2163233A1

  公开（公告）日：2010-03-17

  To provide a paste-type dental cement capable of being used properly for temporary adhering or temporary filling, a paste-type dental cement, which comprises a phosphoric acid and/or a polymer of α-β unsaturated carboxylic acid, an oxide powder capable of reacting with the phosphoric acid and/or the polymer of α-β unsaturated carboxylic acid, and water, further includes a liquid not reacting with the oxide powder.

  为了提供一种能够适当用于临时粘接或临时填充的糊状牙科粘结剂，糊状牙科粘结剂包括磷酸和/或 α-β 不饱和羧酸聚合物、能够与磷酸和/或 α-β 不饱和羧酸聚合物反应的氧化物粉末和水，还包括不与氧化物粉末反应的液体。
• Tooth coating material
  申请人：GC Corporation

  公开号：EP2353576A1

  公开（公告）日：2011-08-10

  To easily confirm a coating state and covering state of a tooth and coating material on a tooth, the tooth coating material is made to be visually confirmable clearer than surrounding teeth by irradiating a fluorescent agent therein with an ultraviolet or visible ray by a dental light irradiator to excite the fluorescent agent, for example, the tooth coating material containing no water, but including: 0.5 to 20% by weight of a caseinphosphopeptide-amorphouscalciumphosphate complex (CPP-ACP) and/or a casein phosphopeptide-amorphous calcium fluoride phosphate complex (CPP-ACFP), 5 to 70% by weight of a covering film- forming polymer, 5 to 70% by weight of an organic solvent selected so as to contain alcohol, 0.01 to 10% by weight of a fluorine compound, 0.1 to 20% by weight of a thickener, and 0.1 to 3% by weight of the fluorescent agent.

  为了方便地确认牙齿和牙齿上涂层材料的涂层状态和覆盖状态，通过牙科光照射器用紫外线或可见光照射其中的荧光剂，激发荧光剂，使牙齿涂层材料比周围的牙齿更清晰，例如，牙齿涂层材料不含水，但包括：0.5-20%（重量）的酪蛋白磷酸肽-无定形磷酸钙复合物（CPP-ACP）和/或酪蛋白磷酸肽-无定形氟化磷酸钙复合物（CPP-ACFP），5-70%（重量）的覆盖成膜聚合物，5-70%（重量）的有机溶剂，有机溶剂的选择是含有酒精，0.01至10%（重量）的氟化合物，0.1至20%（重量）的增稠剂，以及0.1至3%（重量）的荧光剂。
• COMPOSITION FOR THE TREATMENT OF NAIL FUNGUS
  申请人：Oystershell NV

  公开号：EP3884933A1

  公开（公告）日：2021-09-29

  The current invention relates to a composition for the topical treatment of fungal infections in nails, comprising at least one physiologically acceptable carboxylic acid capable of reducing the pH in keratinous tissue, in particular nails, of a treated person below 4.0, preferably in the range of 1.5 - 4.0, a physiologically acceptable carrier comprising at least one C1-C4 alkyl ester of lactic acid, and at least one physiologically acceptable fluorescent whitening agent. The invention relates to the use of said composition for the preparation of a product suitable for treatment of fungal infections. The invention also relates to the use of said composition for the treatment of a fungal infection.

  本发明涉及一种用于局部治疗指甲真菌感染的组合物，该组合物包含至少一种生理上可接受的羧酸，该羧酸能够将受治疗者的角质组织（尤其是指甲）中的 pH 值降至 4.0 以下，最好在 1.5 - 4.0 之间；一种生理上可接受的载体，该载体包含至少一种乳酸的 C1-C4 烷基酯；以及至少一种生理上可接受的荧光增白剂。本发明涉及使用所述组合物制备适用于治疗真菌感染的产品。本发明还涉及使用所述组合物治疗真菌感染。
• Reinforcement of the effect of optical brighteners by means of polymers
  申请人：——

  公开号：US20040238791A1

  公开（公告）日：2004-12-02

  Pigment-free mixtures, containing a) at least one optical brightener and b) at least one (co)polymer, with at least one N-vinylcarboxamide incorporated in the polymer and/or at least one nitrogen-containing heterocyclic ring and/or which may form a nitrogen-containing heterocyclic ring.

  不含颜料的混合物，含有 a) 至少一种光学增白剂和 b) 至少一种（共）聚合物，聚合物中含有至少一种 N-乙烯基甲酰胺和/或至少一种含氮杂环和/或可形成含氮杂环。