摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词

3-Methoxy-5-(2-methyl-1,3-dioxolan-2-yl)cyclohexa-3,5-diene-1,2-dione | 926906-98-1

中文名称
——
中文别名
——
英文名称
3-Methoxy-5-(2-methyl-1,3-dioxolan-2-yl)cyclohexa-3,5-diene-1,2-dione
英文别名
——
3-Methoxy-5-(2-methyl-1,3-dioxolan-2-yl)cyclohexa-3,5-diene-1,2-dione化学式
CAS
926906-98-1
化学式
C11H12O5
mdl
——
分子量
224.213
InChiKey
PKEXNKMFBJPMSW-UHFFFAOYSA-N
BEILSTEIN
——
EINECS
——
  • 物化性质
  • 计算性质
  • ADMET
  • 安全信息
  • SDS
  • 制备方法与用途
  • 上下游信息
  • 反应信息
  • 文献信息
  • 表征谱图
  • 同类化合物
  • 相关功能分类
  • 相关结构分类

计算性质

  • 辛醇/水分配系数(LogP):
    -0.3
  • 重原子数:
    16
  • 可旋转键数:
    2
  • 环数:
    2.0
  • sp3杂化的碳原子比例:
    0.45
  • 拓扑面积:
    61.8
  • 氢给体数:
    0
  • 氢受体数:
    5

反应信息

点击查看最新优质反应信息

文献信息

  • Total synthesis of cleomiscosin C via a regioselective cycloaddition reaction of o-quinone
    作者:Atsuhito Kuboki、Chie Maeda、Tetsuya Arishige、Kohei Kuyama、Mami Hamabata、Susumu Ohira
    DOI:10.1016/j.tetlet.2008.05.051
    日期:2008.7
    We have achieved total synthesis of cleomiscosin C (aquillochin) through regioselective cycloaddition of o-quinone and protected sinapyl alcohol as a key step. During preparation of o-quinone from phenol by IBX oxidation, silyl substituents adjacent to the phenolic hydroxyl group afforded effective inhibition of an undesired oxidative elimination. (c) 2008 Elsevier Ltd. All rights reserved.
  • Inverse electron demand hetero-Diels–Alder reaction in preparing 1,4-benzodioxin from o-quinone and enamine
    作者:Jinsong Zhang、Chris Taylor、Erich Bowman、Leo Savage-Low、Michael W. Lodewyk、Larry Hanne、Guang Wu
    DOI:10.1016/j.tetlet.2013.09.013
    日期:2013.11
    A process for synthesizing 1,4-benzodioxin, through oxidation of a phenol to an o-quinone followed by treatment with an enamine, has been developed. Adduct stereochemistry is found to be retained via this one-pot reaction. The method uses hypervalent iodine reagent under mild conditions and is compatible with a wide scope of phenols and enamines. Published by Elsevier Ltd.
  • Total synthesis of (±)-nitidanin and novel procedures for determination of the location of the side chains on 1,4-benzodioxane
    作者:Atsuhito Kuboki、Toru Yamamoto、Mamie Taira、Tetsuya Arishige、Susumu Ohira
    DOI:10.1016/j.tetlet.2006.11.170
    日期:2007.1
    Regioselective cycloaddition of o-quinone 4 and protected sinapyl alcohol 2 gave 1,4-benzodioxane 5, which was converted to (+/-)-nitidanin (6), an antimalarial compound. Two novel procedures were developed to determine the location of the side chains of the adduct (5) based on partial ring cleavage. (c) 2006 Elsevier Ltd. All rights reserved.
查看更多