苯甲醇,3,4-二甲氧基-a-[1-(2-甲氧基苯氧基)乙基]- | 1835-10-5

• 分子结构分类: 有机化合物 - 木脂素、新木脂素和相关化合物
• 中文名称: 苯甲醇,3,4-二甲氧基-a-[1-(2-甲氧基苯氧基)乙基]-
• 英文名称: 3,4-Dimethoxy-α-<(2-methoxyphenoxy)methyl>benzenemethanol
• 英文别名: 1-(3,4-dimethoxyphenyl)-2-(2-methoxyphenoxy)propan-1-ol；Methylisoeugenolglykol-β-guajacylaether；2-<2-Methoxy-phenoxy>-1-<3,4-dimethoxy-phenyl>-propanol-(1)；1-(3,4-Dimethoxy-phenyl)-2-(2-methoxy-phenoxy)-propanol-(1)；1,2-Dimethoxy-4-<2-(2-methoxy-phenoxy)-1-hydroxy-propyl>-benzol；2-(2-Methoxy-phenoxy)-1-(3,4-dimethoxy-phenyl)-propanol
• CAS: 1835-10-5
• 化学式: C₁₈H₂₂O₅
• 分子量: 318.37
• InChiKey: AHOFBNJIUMOJOW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  23
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  57.2
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  苯甲醇,3,4-二甲氧基-a-[1-(2-甲氧基苯氧基)乙基]- 在 barium sulfate 、 palladium dichloride 氢气 作用下， 以 溶剂黄146 为溶剂， 生成 1-(3,4-Dimethoxy-phenyl)-2-propyl-(2-methoxy-phenyl)-ether
  参考文献：
  名称：

  Adler,E.; Marton,J., Acta Chemica Scandinavica (1947), 1961, vol. 15, p. 357 - 369

  摘要：

  DOI：
• 作为产物：
  描述：

  2-溴-3-4-二甲氧基苯丙酮 在 sodium tetrahydroborate 、 potassium carbonate 作用下， 以 甲醇 、 丙酮 为溶剂， 反应 0.5h， 生成 苯甲醇,3,4-二甲氧基-a-[1-(2-甲氧基苯氧基)乙基]-
  参考文献：
  名称：

  Electroorganic reactions. 38. Mechanism of electrooxidative cleavage of lignin model dimers

  摘要：

  The mechanisms for oxidative cleavage of several phenolic ethers, models for lignins, have been investigated by a detailed comparison of the result of anodic oxidation at nickel anodes in alkaline electrolyte with that of oxidation in acetonitrile in the presence of a triarylamine redox catalyst. The latter reaction is unambiguously initiated by single-electron transfer (SET), and in this case the major product of cleavage is aldehyde (vanillin or syringaldehyde derivatives). At nickel anodes polymerization is predominant although the aldehydes are formed together with larger amounts of the corresponding carboxylic acids. Combinations of 4-hydroxyl, alpha-keto, beta-O-aryl, and beta-hydroxymethyl functionality are shown to be crucial for the oxidation at nickel; the carboxylic acid formation probably involves a route with initial hydrogen atom abstraction at the surface. Important chemical conversions precede and accompany oxidation in alkaline media, and these are associated with the propensity for polymerization.

  DOI：

  10.1021/jo00026a022

文献信息

• Gieser,J.; Noren,I., Acta Chemica Scandinavica (1947), 1962, vol. 16, p. 1713 - 1729
  作者：Gieser,J.、Noren,I.

  DOI：——

  日期：——
• Adducts of anthrahydroquinone and anthranol with lignin model quinone methides. 3. Independent synthesis of threo and erythro isomers
  作者：John Ralph、Lawrence L. Landucci

  DOI：10.1021/jo00170a003

  日期：1983.11
• GRABKINA, O. A.;BABKIN, V. A.;MEDVEDEVA, S. A.;IVANOVA, S. Z.;PAVLINSKIJ,+, XIMIYA DREVESINY,(1987) N 5, 34-40, 121, 122
  作者：GRABKINA, O. A.、BABKIN, V. A.、MEDVEDEVA, S. A.、IVANOVA, S. Z.、PAVLINSKIJ,+

  DOI：——

  日期：——