dimethyl 2-[1-(4-chlorophenyl)-3-phenylallyl]malonate | 879480-41-8

• 分子结构分类: 有机化合物 - 木脂素、新木脂素和相关化合物
• 英文名称: dimethyl 2-[1-(4-chlorophenyl)-3-phenylallyl]malonate
• CAS: 879480-41-8
• 化学式: C₂₀H₁₉ClO₄
• 分子量: 358.821
• InChiKey: XJKRNRRBGTWJHW-KRWDZBQOSA-N

反应信息

• 作为产物：
  描述：

  丙二酸二甲酯 、 在 N,O-双三甲硅基乙酰胺 、 bis(η3-allyl-μ-chloropalladium(II)) 、 C₃₉H₃₆FeP₂ 、 potassium acetate 作用下， 以 二氯甲烷 为溶剂， 反应 13.0h， 生成 dimethyl 2-[3-(4-chlorophenyl)-1-phenylallyl]malonate 、 dimethyl 2-[1-(4-chlorophenyl)-3-phenylallyl]malonate 、 dimethyl 2-[3-(4-chlorophenyl)-1-phenylallyl]malonate 、 dimethyl 2-[1-(4-chlorophenyl)-3-phenylallyl]malonate
  参考文献：
  名称：

  Asymmetric allylic substitutions on symmetrical and non-symmetrical substrates using [5]ferrocenophane ligands

  摘要：

  A series of [5]ferrocenophane diphosphane ligands were used in Pd-catalyzed allylic substitution reactions. With a symmetrical substrate, 1,3-diphenylpropenyl acetate, enantioselectivities between 70% and 94% ee were observed. Several non-symmetrically substituted allylic substrates were also used. Depending on the substituents of the non-symmetrical allylic substrates, various degrees of regioselectivity (from 1:1 to 100:0) and enantioselectivity (from 0% to 96% ee) were observed. Tentative catalytically active complexes were studied by DFT computational methods. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2010.05.054