| 1308769-78-9

• 分子结构分类: 有机化合物 - 木脂素、新木脂素和相关化合物
• CAS: 1308769-78-9
• 化学式: C₂₁H₂₀O₅
• 分子量: 352.387
• InChiKey: GAZMLFBDGPICSY-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  在 potassium permanganate 、 copper(ll) sulfate pentahydrate 、 potassium carbonate 作用下， 以 二氯甲烷 、 丙酮 为溶剂， 反应 74.0h， 生成 5,6,7-trimethoxy-4-(4-methoxyphenyl)-3H-benzo[f][2]benzofuran-1-one
  参考文献：
  名称：

  A Garratt–Braverman route to aryl naphthalene lignans

  摘要：

  A series of aryl naphthalene lignans were prepared in good yields starting from substituted bis-propargyl ethers. The method involved a base-mediated Garratt-Braverman cyclization followed by benzylic oxidation to the lactone. The chemoselectivity in the GB cyclization and the regioselectivity in the benzylic oxidation could be achieved by controlling the electronic nature of the aryl-substituents as well as by changing the substitution pattern of the two aryl rings. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.01.011
• 作为产物：
  描述：

  [4-[3-[3-(3,4,5-Trimethoxyphenyl)prop-2-ynoxy]prop-1-ynyl]phenyl] benzoate 在 potassium tert-butylate 作用下， 以 甲苯 为溶剂， 反应 3.0h， 以98%的产率得到
  参考文献：
  名称：

  A Garratt–Braverman route to aryl naphthalene lignans

  摘要：

  A series of aryl naphthalene lignans were prepared in good yields starting from substituted bis-propargyl ethers. The method involved a base-mediated Garratt-Braverman cyclization followed by benzylic oxidation to the lactone. The chemoselectivity in the GB cyclization and the regioselectivity in the benzylic oxidation could be achieved by controlling the electronic nature of the aryl-substituents as well as by changing the substitution pattern of the two aryl rings. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.01.011