15,15'-didehydro-4'-apo-β,ψ-caroten-4'-al | 13220-02-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 15,15'-didehydro-4'-apo-β,ψ-caroten-4'-al
• 英文别名: 15,15'-Didehydro-4'-apo-β,ψ-carotin-4'-al
• CAS: 13220-02-5
• 化学式: C₃₅H₄₄O
• 分子量: 480.734
• InChiKey: GUSOXZKDBBZDDE-ZALWGBOHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.67
• 重原子数：
  36.0
• 可旋转键数：
  9.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.34
• 拓扑面积：
  17.07
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为反应物：
  描述：

  15,15'-didehydro-4'-apo-β,ψ-caroten-4'-al 在 喹啉 、 Lindlar's catalyst 、 甲苯 作用下， 生成 β-Apo-4'-carotinal
  参考文献：
  名称：

  类胡萝卜素系列的合成。15.β-胡萝卜素和β-胡萝卜素系列中的交流合成† ‡ §

  摘要：

  为了研究对胡萝卜素在动物体内氧化降解为维生素A的方法，已制备了许多可能的中间体。首先，通过连续的烯醇醚缩合反应合成了15,15'-脱氢-β-apo-12'-胡萝卜素（C 25）乙烯基系列多烯醛和具有25至40个碳原子的乙酸酯。合成的β-apo-8'-胡萝卜素（C 30）和β-apo-8'-胡萝卜素（C 30）与β-胡萝卜素的高锰酸盐氧化产物及其相应的醇（通过KARRER分离）相同。

  DOI：

  10.1002/hlca.19590420328
• 作为产物：
  描述：

  15,15'-didehydro-6'-apo-β-caroten-6'-al-diethylacetal 在 二氯甲烷 、 乙基丙烯醚 、 zinc(II) chloride 作用下， 生成 15,15'-didehydro-4'-apo-β,ψ-caroten-4'-al
  参考文献：
  名称：

  类胡萝卜素系列的合成。15.β-胡萝卜素和β-胡萝卜素系列中的交流合成† ‡ §

  摘要：

  为了研究对胡萝卜素在动物体内氧化降解为维生素A的方法，已制备了许多可能的中间体。首先，通过连续的烯醇醚缩合反应合成了15,15'-脱氢-β-apo-12'-胡萝卜素（C 25）乙烯基系列多烯醛和具有25至40个碳原子的乙酸酯。合成的β-apo-8'-胡萝卜素（C 30）和β-apo-8'-胡萝卜素（C 30）与β-胡萝卜素的高锰酸盐氧化产物及其相应的醇（通过KARRER分离）相同。

  DOI：

  10.1002/hlca.19590420328

文献信息

• Testing the requirements of stages of physical activity among adults: The comparative effectiveness of stage-matched, mismatched, standard care, and control interventions
  作者：Bryan Blissmer、Edward McAuley

  DOI：10.1207/s15324796abm2403_03

  日期：2002.8

  We tested the comparative efficacy of 4 interventions to increase the physical activity behavior of college personnel randomly assigned to one condition (N = 196, 74% female, M age = 43.4 years) for 16 weeks. Stage-matched and mismatched interventions were developed based on the stages of change from the Transtheoretical Model and were contrasted with standard care (action-oriented) and control interventions to test the requirements of a true stage behavior Repeated measures of multivariate analyses of covariance indicated that the stage-matched and standard care interventions resulted in greater levels of both total and lifestyle physical activity compared with the mismatched and control interventions. The results supported the requirements of a stage behavior as defined by Weinstein, Rothman, and Sutton (1) and the superiority of the stage-matched intervention versus the mismatched intervention. However, the standard care intervention performed as well as the matched intervention, suggesting the need for further investigation. The results are discussed with respect to the high proportion of individuals in the action-oriented stages and previous research findings in the smoking literature.