cis-1-Ethyl-4-tert-butyl-cyclohexan | 1129-24-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: cis-1-Ethyl-4-tert-butyl-cyclohexan
• CAS: 1129-24-4
• 化学式: C₁₂H₂₄
• 分子量: 168.323
• InChiKey: JMUSIRQLHNHLKA-PHIMTYICSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.25
• 重原子数：
  12.0
• 可旋转键数：
  1.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0.0
• 氢给体数：
  0.0
• 氢受体数：
  0.0

反应信息

• 作为产物：
  描述：

  4-tert-butyl-1-ethylidene-cyclohexane 在 palladium on activated charcoal 氢气 作用下， 以 乙醇 为溶剂， 生成 trans-1-Ethyl-4-tert.-butyl-cyclohexan 、 cis-1-Ethyl-4-tert-butyl-cyclohexan
  参考文献：
  名称：

  Diastereoselectivity in the heterogeneous hydrogenation reactions of phosphorous substituted olefins

  摘要：

  Phosphorous substituted methylenecyclohexane olefins show enhanced diastereoselectivity in heterogeneous hydrogenation reactions using Pd/C. A model system derived from 4-t-butylcyclohexanone was used to explore the effects of solvent polarity and catalyst on the reduction reaction. It was found that olefins hydrogenated with catalytic Pd/C in polar solvents afford the highest diastereoselectivities (>15:1). (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(97)10371-9

文献信息

• Diastereoselectivity in the heterogeneous hydrogenation reactions of phosphorous substituted olefins
  作者：Bret E. Huff、Vien V. Khau、Michael E. LeTourneau、Michael J. Martinelli、Naresh K. Nayyar、Barry C. Peterson

  DOI：10.1016/s0040-4039(97)10371-9

  日期：1997.12

  Phosphorous substituted methylenecyclohexane olefins show enhanced diastereoselectivity in heterogeneous hydrogenation reactions using Pd/C. A model system derived from 4-t-butylcyclohexanone was used to explore the effects of solvent polarity and catalyst on the reduction reaction. It was found that olefins hydrogenated with catalytic Pd/C in polar solvents afford the highest diastereoselectivities (>15:1). (C) 1997 Elsevier Science Ltd.