Compositions comprising encapsulated actives within droplets and other compartments
申请人:The Procter & Gamble Company
公开号:US10434485B2
公开(公告)日:2019-10-08
The present invention generally relates to microparticles and, in particular, to systems and methods for encapsulation within microparticles. In one aspect, the present invention is generally directed to microparticles containing entities therein, where the entities contain an agent that can be released from the microparticles, e.g., via diffusion. In some cases, the agent may be released from the microparticles without disruption of the microparticles. The entities may be, for instance, polymeric particles, hydrogel particles, droplets of fluid, etc. The entities may be contained within a fluid that is, in turn, encapsulated within the microparticle. The agent may be released from the entity into the fluid, and then from the fluid through the microparticle. In such fashion, the release of agent from the microparticle may be controlled, e.g., over relatively long time scales. Other embodiments of the present invention are generally directed to methods of making such microparticles, methods of using such microparticles, microfluidic devices for making such microparticles, and the like.
本发明一般涉及微粒,特别是涉及在微粒内封装的系统和方法。在一个方面,本发明一般针对其中含有实体的微粒,实体中含有可通过扩散等方式从微粒中释放的药剂。在某些情况下,药剂可以在不破坏微颗粒的情况下从微颗粒中释放出来。实体可以是聚合物颗粒、水凝胶颗粒、液滴等。实体可以包含在流体中,而流体又封装在微粒中。药剂可以从实体释放到流体中,然后通过微粒从流体中释放出来。通过这种方式,可以控制药剂从微粒子中的释放,例如在相对较长的时间范围内。本发明的其它实施方案一般针对制造此类微粒的方法、使用此类微粒的方法、制造此类微粒的微流体设备等。