Biofilms are provided which are capable of regulating their own thickness, reducing contamination and preventing biofouling. Constructs are introduced into bacteria that comprise nucleic acid molecules encoding an autoinducer synthase polypeptide, a transcriptional regulator and a biofilm dispersal protein. Nucleic acid molecules may also be introduced which encode a nitric oxide synthase, an epoxide hydrolase, or both. Biofilms of the bacteria may be used to reduce biofouling and contamination of a surface.
所提供的
生物膜能够调节自身厚度、减少污染和防止
生物污染。将包含编码自诱导合成酶
多肽、转录调节器和
生物膜分散蛋白的核酸分子的构建物引入细菌。还可以引入编码
一氧化氮合酶、
环氧化物水解酶或两者的核酸分子。细菌的
生物膜可用于减少表面的
生物污损和污染。