sucrose 1'-O-methacrylate | 163803-37-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: sucrose 1'-O-methacrylate
• 英文别名: [(2S,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxolan-2-yl]methyl 2-methylprop-2-enoate
• CAS: 163803-37-0
• 化学式: C₁₆H₂₆O₁₂
• 分子量: 410.375
• InChiKey: IUXYZXYRGINANE-IUHJZARWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.7
• 重原子数：
  28
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.81
• 拓扑面积：
  196
• 氢给体数：
  7
• 氢受体数：
  12

反应信息

• 作为反应物：
  描述：

  月桂酸乙烯酯 、 sucrose 1'-O-methacrylate 在 lipase Novozym 435 from Candida antarctica 作用下， 以 叔丁醇 为溶剂， 反应 12.0h， 以72%的产率得到sucrose 6'-O-monolaurate 1'-O-monomethacrylate
  参考文献：
  名称：

  Lipase-Catalysed Selective Synthesis of Sucrose Mixed Diesters

  摘要：

  研究了脂肪酶催化的蔗糖酯化反应与活化和非活化酰基供体反应的选择性。使用 Novozym 435 脂肪酶，可以获得高转化率和高选择性的蔗糖脂肪酸二酯和混合脂肪酸甲基丙烯酸二酯。

  DOI：

  10.1055/s-2001-11436
• 作为产物：
  描述：

  甲基丙烯酸三氟乙酯 、 蔗糖 在 proteinase N 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 生成 sucrose 1'-O-methacrylate
  参考文献：
  名称：

  Proteinase N-catalysed transesterifications in DMSO–water and DMF–water: preparation of sucrose monomethacrylate

  摘要：

  The selective acylation of sucrose was catalysed by proteinase N (from Bacillus subtilis) in DMF suspensions, providing 1'-monoesters, and notably, methacryloyl esters. Presence of water up to 7% (vol.) led to faster reactions. Alternatively, a slurry of the enzyme with a minimum volume of DMSO could also be used, despite its ability to denature enzymes. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(00)00452-4

文献信息

• Compositions comprising low-DP polymerized surfactants and methods of use thereof
  申请人：Fevola J. Michael

  公开号：US20070259797A1

  公开（公告）日：2007-11-08

  Provided are low-irritation personal care compositions comprising a low-DP polymerized surfactants. Also provided are methods of making and using such compositions.

  提供了低刺激性个人护理配方，其中包括低DP聚合表面活性剂。还提供了制备和使用这种配方的方法。
• Immobilized buffered gels and membranes of hydroxy groups containing polymers
  申请人：ALIGENA AG

  公开号：EP0572354A2

  公开（公告）日：1993-12-01

  Immobilized buffered gels obtained from hydroxy group containing natural or synthetic polymers and acid or basic di- or triazine derivatives are useful and highly effective media, e.g. in form of membranes, for preparative isoelectric focusing electrophoresis for separating high molecular compounds, such as proteins or peptides, from biological mixtures.

  由含羟基的天然或合成聚合物和酸性或碱性二嗪或三嗪衍生物制成的固定缓冲凝胶是一种有用且高效的介质，例如以膜的形式，用于制备等电聚焦电泳，从生物混合物中分离高分子化合物，如蛋白质或肽。
• Copolymers of (meth)acryloxy-alkyl-siloxysilane and alkyl(meth)acrylates and the use thereof as pressure sensitive adhesives
  申请人：CIBA-GEIGY AG

  公开号：EP0611783A1

  公开（公告）日：1994-08-24

  The present invention relates to copolymers of certain siloxy silanes and alkyl (meth)acrylate. Especially preferred is the embodiment wherein the silyloxy silane is 3-methacryloxypropyl-tris(trimethylsilyloxy)-silane and the alkyl (meth)acrylate is 2-ethylhexyl acrylate. It further relates to pressure sensitive adhesives, especially medical adhesives, suitable for use in transdermal therapeutic systems (TTS).

  本发明涉及某些硅氧基硅烷和烷基（甲基）丙烯酸酯的共聚物。特别优选的是硅氧基硅烷为 3-甲基丙烯酰氧基丙基-三（三甲基硅氧基）硅烷，烷基（甲基）丙烯酸酯为 2-乙基己基丙烯酸酯。它还涉及适用于透皮治疗系统（TTS）的压敏粘合剂，特别是医用粘合剂。
• Compositions comprising a low-dp polymerized surfactant and a micellar thickener
  申请人：Johnson & Johnson Consumer Companies, Inc.

  公开号：EP2314275A2

  公开（公告）日：2011-04-27

  Provided are healthcare compositions comprising a low-DP polymerized surfactant, a micellar thickener, and a cosmetically-acceptable or pharmaceutically-acceptable carrier. Also, provided are methods of cleansing or treating a mammal by applying healthcare compositions of the present inventions to the mammalian body.

  本发明提供的保健组合物包含低密度聚合表面活性剂、胶束增稠剂和化妆品可接受或药学可接受的载体。此外，还提供了通过在哺乳动物体内施用本发明的保健组合物来清洁或治疗哺乳动物的方法。
• Compositions comprising superhydrophilic amphiphilic copolymers and methods of use thereof
  申请人：Johnson & Johnson Consumer Companies, Inc.

  公开号：EP2314273A2

  公开（公告）日：2011-04-27

  Provided are compositions comprising a superhydrophilic amphiphilic copolymer and a carrier and composition comprising a superhydrophilic amphiphilic copolymer, a micellar thickener and a carrier.

  提供了由超亲水两亲共聚物和载体组成的组合物，以及由超亲水两亲共聚物、胶束增稠剂和载体组成的组合物。