1-(2-羟基苯基)辛烷-1-酮 | 3226-27-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 1-(2-羟基苯基)辛烷-1-酮
• 英文名称: 2'-Hydroxyoctanophenon
• 英文别名: 1-(2-hydroxy-phenyl)-octan-1-one；1-(2-Hydroxy-phenyl)-octan-1-on；1-Octanone, 1-(2-hydroxyphenyl)-；1-(2-hydroxyphenyl)octan-1-one
• CAS: 3226-27-5
• 化学式: C₁₄H₂₀O₂
• 分子量: 220.312
• InChiKey: PGCCZWYHMDVUBU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  16
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-(2-羟基苯基)辛烷-1-酮 在 吡啶 、 乙酸铵 、 sodium hydroxide 、 氯化亚砜 、 乙醇 、 硫酸 、 溶剂黄146 、 苯 作用下， 生成 4-heptyl-2-oxo-2H-chromene-3-carboxylic acid ethyl ester
  参考文献：
  名称：

  The Synthesis of Various 3-Substituted-4-alkylcoumarins¹

  摘要：

  DOI：

  10.1021/ja01576a059
• 作为产物：
  描述：

  4’-羟基苯辛酮 在 三氯化铝 作用下， 生成 1-(2-羟基苯基)辛烷-1-酮
  参考文献：
  名称：

  ORIENTATION IN THE FRIES REARRANGEMENT OF PHENYL CAPRYLATE

  摘要：

  DOI：

  10.1021/jo01205a010

文献信息

• Method of catalytic crosslinking of polymers and two-pack composition used therein
  申请人：ROHM AND HAAS COMPANY

  公开号：EP0950669A2

  公开（公告）日：1999-10-20

  A method of crosslinking an oxidative polymer having oxidatively crosslinkable functional groups and a two-pack composition used therein. The oxidatively crosslinkable functional groups on the oxidative polymer are crosslinked by contacting the oxidative polymer with a catalytic amount of an oxidizing enzyme, such as horseradish peroxidase. The present invention is further directed to a two-pack coating composition which includes a polymeric component and a catalytic component, which are mixed together prior to use.

  一种交联具有可氧化交联官能团的氧化聚合物及其所用双组分组合物的方法。通过将氧化聚合物与催化量的氧化酶（如辣根过氧化物酶）接触，使氧化聚合物上的可氧化交联官能团交联。本发明还涉及一种双包装涂层组合物，它包括一种聚合物成分和一种催化成分，在使用前将它们混合在一起。
• Stepniak-Biniakiewicz, Danuta, Polish Journal of Chemistry, 1980, vol. 54, # 7/8, p. 1567 - 1571
  作者：Stepniak-Biniakiewicz, Danuta

  DOI：——

  日期：——
• Pigment epithelial detachment in the elderly
  作者：D. Pauleikhoff、D. Löffert、G. Spital、M. Radermacher、J. Dohrmann、A. Lommatzsch、A. Bird

  DOI：10.1007/s00417-002-0505-8

  日期：2002.7

  Background: A prospective analysis was performed to characterize the angiographic appearance, natural course and prognosis of serous pigment epithelial detachments (PEDs) in elderly patients. The aim was to differentiate PEDs according to their angiographic characteristics and to analyze the specific clinical, visual and morphologic course of the different PEDs. Methods: Fluorescein and indocyanine green angiography were performed in 10 1 consecutive patients (53-87 years; 63 female, 38 male) with clinical signs of serous PED and drusen. Results: Different types of serous PED were identified: polypoidal choroidal vasculopathy (PCV)-associated PED in 14 patients (13.9%), vascular PED in 72 (71.2%), and avascular PED in 15 (14.9%). All PEDs resulted initially in similar visual loss. Avascular PEDs were smaller than vascular PEDs, and the latter were smaller than PCV-PEDs. During follow-up these differences were always present, but all PEDs enlarged initially followed by regression. This course was associated in all PEDs with progressive visual loss, accompanied by the development of RPE atrophy in avascular PEDs or disciform scars or RPE tears in the two other types. Conclusion: Despite different associations, all PEDs have a similar clinical course with respect to visual loss and enlargement or regression. This is compatible with the proposed common pathogenetic background with a hydrophobic barrier in Bruch's membrane causing fluid resulting from RPE pumping activity to accumulate between the pigment epithelium and Bruch's membrane.
• Ralston; Bauer, Journal of Organic Chemistry, 1940, vol. 5, p. 169
  作者：Ralston、Bauer

  DOI：——

  日期：——
• ORIENTATION IN THE ACYLATION OF PHENOL AND IN THE REARRANGEMENT OF PHENOLIC ESTERS
  作者：A. W. RALSTON、M. R. McCORKLE、S. T. BAUER

  DOI：10.1021/jo01212a011

  日期：1940.11