4,7,7-三甲基-2,3-二氧代双环[2.2.1]庚烷-1-羧酸 | 69842-14-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 中文名称: 4,7,7-三甲基-2,3-二氧代双环[2.2.1]庚烷-1-羧酸
• 中文别名: 4,7,7-三甲基-2,3-二氧代-双环[2.2.1]庚烷-1-羧酸
• 英文名称: 4,7,7-trimethyl-2,3-dioxo-norbornane-1-carboxylic acid
• 英文别名: Campherchinon-carbonsaeure-(4)；Camphandion-(2.3)-carbonsaeure-(4)；4,7,7-Trimethyl-2,3-dioxo-norbornan-1-carbonsaeure；4.7.7-Trimethyl-bicyclo-[1.2.2]-heptandion-(2.3)-carbonsaeure-(1)；4,7,7-Trimethyl-2,3-dioxobicyclo[2.2.1]heptane-1-carboxylic acid
• CAS: 69842-14-4
• 化学式: C₁₁H₁₄O₄
• 分子量: 210.23
• InChiKey: MFGSQXUNSUJWPZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  71.4
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  3,3-二甲基-2-亚甲基-双环[2.2.1]-庚烷-1-羧酸 在 sodium hydroxide 、 natrium carbonatalkaline permanganate 、 硫酸 、 sodium amide 、 sodium hydrogensulfite 、 溶剂黄146 、 苯 作用下， 生成 4,7,7-三甲基-2,3-二氧代双环[2.2.1]庚烷-1-羧酸
  参考文献：
  名称：

  Houben; Pfankuch, Chemische Berichte, 1926, vol. 59, p. 2296

  摘要：

  DOI：

文献信息

• Camphorquinone Derivative Having Acylphosphine Oxide Group, Photopolymerization Catalyst And Photo/Chemical Polymerization Catalyst Containing The Same And Hardenable Composition Contaning The Same
  申请人：Ikemura Kunio

  公开号：US20090105361A1

  公开（公告）日：2009-04-23

  A compound that exhibits excellent color tone stability and physical properties as well as excellent photopolymerization activity over a wide region from near-ultraviolet to visible region, permitting relaxed operation under ambient light, so that wide application can be found in the dental field and photopolymerization industry; and a relevant photopolymerization initiator and hardenable composition. In particular, there is provided a novel camphorquinone derivative having an acylphosphine oxide group [—(C═O)—(P═O)<] in each molecule. Further, there is provided a photopolymerization initiator comprising the camphorquinone derivative having an acrylphosphine oxide group [—(C═O)—(P═O)<] in each molecule as an indispensable component, loaded with at least one member selected from among a polymerization accelerator, a photoacid generator, a photosensitizer and a (bis)acylphosphine oxide, and provided a hardenable composition comprising the initiator. The thus provided photopolymerization initiator and hardenable composition exhibit excellent color tone stability and physical properties as well as excellent photopolymeritzaion activity over an ultraviolet and visible wide wavelength region, permitting relaxed operation under ambient light, so that wide application can be found in the dental field and photopolymerization industry.

  提供了一种化合物，其具有出色的色调稳定性和物理性能，以及在近紫外到可见光区域内具有优异的光聚合活性，使得在环境光线下可以放松操作，因此在牙科领域和光聚合工业中可以找到广泛的应用；以及相关的光聚合引发剂和可硬化组合物。特别地，提供了一种新型的萜烯酮衍生物，其每个分子中都具有一个酰基膦氧化物基团[—(C═O)—(P═O)<]。此外，还提供了一种光聚合引发剂，其中包含具有丙烯酰膦氧化物基团[—(C═O)—(P═O)<]的萜烯酮衍生物作为不可或缺的组分，装载有至少一种从聚合促进剂、光酸发生剂、光敏剂和(双)酰基膦氧化物中选择的成员，并提供了一种包含引发剂的可硬化组合物。因此，所提供的光聚合引发剂和可硬化组合物在紫外和可见光宽波长区域内表现出优异的色调稳定性和物理性能，以及优异的光聚合活性，使得在环境光线下可以放松操作，因此在牙科领域和光聚合工业中可以找到广泛的应用。
• Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds
  申请人：Zhou Yuefen

  公开号：US20070197533A1

  公开（公告）日：2007-08-23

  The invention relates to antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds and pharmaceutical compositions thereof. This invention also relates to a method of using such compounds in the treatment of bacterial infections in mammals, especially humans.

  本发明涉及抗菌性3,5-二氨基哌啶取代的芳香和杂环化合物及其制药组合物。本发明还涉及使用这些化合物治疗哺乳动物（尤其是人类）细菌感染的方法。
• Reaction-Curable Adhesive Composition and Dental Adhesive Kit
  申请人：Yamamoto Takashi

  公开号：US20100292359A1

  公开（公告）日：2010-11-18

  A reaction-curable adhesive composition exhibiting acidity is formed form a weakly acidic to alkaline composition (I) comprising (a) a polymerizable monomer and (b) a compound represented by the following formula (1) and a strongly acidic composition (II) comprising (a) a polymerizable monomer. R 1 —C 6 H 4 —NR 2 CH 2 COOR 3 (1) wherein R 1 and R 2 are each independently a hydrogen atom or an alkyl group which may have a functional group, and R 3 is a hydrogen atom or a metal atom. The composition containing the polymerizable monomer can be stably stored for a long period of time.

  一种表现出酸性的反应固化粘合剂组合物是由一个弱酸性至碱性的组合物(I)和一个强酸性的组合物(II)形成的。组合物(I)包括(a)可聚合单体和(b)由以下式子(1)表示的化合物，而组合物(II)包括(a)可聚合单体。R1—C6H4—NR2CH2COOR3(1)，其中R1和R2各自独立地是氢原子或可能具有功能基团的烷基基团，而R3是氢原子或金属原子。含有可聚合单体的组合物可以稳定地储存长时间。
• Dental adhesive kit
  申请人：SUN MEDICAL CO., LTD.

  公开号：EP0923924A2

  公开（公告）日：1999-06-23

  A kit for dental adhesive comprising a radical polymerizable monomer having an acid group in the molecule, a photosensitizer and/or a peroxide, a water-soluble organic solvent, an organic sulfinic acid and/or a salt thereof or a barbituric acid and/or a derivative thereof, and water. The kit may further comprises a radical polymerizable monomer which has no acid group and is insoluble or hardly soluble in water, an amine compound, a silane coupling agent and a 1,3,5-triazine-2,4-dithion derivative. By using this kit, the adhesive composition can be applied directly to a dentine without conducting a pretreatment.

  一种牙科粘合剂试剂盒，包括分子中含有酸基的可自由基聚合单体、光敏剂和/或过氧化物、水溶性有机溶剂、有机亚硫酸和/或其盐或巴比妥酸和/或其衍生物以及水。该试剂盒还可进一步包含不含酸基且不溶于或难溶于水的自由基可聚合单体、胺化合物、硅烷偶联剂和 1,3,5-三嗪-2,4-二硫杂环衍生物。使用这种试剂盒，粘合剂组合物可以直接涂抹在牙本质上，而无需进行预处理。
• Photopolymerization initiator
  申请人：Tokuyama Corporation

  公开号：EP1457190A1

  公开（公告）日：2004-09-15

  A photopolymerization initiator comprising (A) an α-diketone compound such as camphorquinone, (B1) an aliphatic amine compound such as triethanolamine or N-methyldiethanolamine, (B2) an aromatic amine compound such as ethyl p-dimethylaminobenzoate or N,N-dimethyl p-toluidine, and (C) a triazine compound substituted with a trihalomethyl group, such as 2,4,6-tris(trichloromethyl)-s-triazine or 2-phenyl-4,6-bis(trichloromethyl)-s-triazine. The photopolymerization initiator remains stable against the environmental light such as the indoor illumination light from a fluorescent lamp or the dental light illuminating the interior of the oral cavity, is excellently handled, is quickly cured by the irradiation with an intense light emitted from a light irradiator for polymerization, provides a cured body having excellent properties, can be stably preserved even at high temperatures, and is very useful as a dental composite resin.

  一种光聚合引发剂，包括(A)α-二酮化合物，如樟脑醌；(B1)脂肪族胺化合物，如三乙醇胺或 N-甲基二乙醇胺；(B2)芳香族胺化合物，如对二甲氨基苯甲酸乙酯或 N、(C) 被三卤甲基取代的三嗪化合物，如 2,4,6-三（三氯甲基）-s-三嗪或 2-苯基-4,6-双（三氯甲基）-s-三嗪。这种光聚合引发剂对环境光（如荧光灯的室内照明光或照亮口腔内部的牙科照明光）保持稳定，操作性极佳，经聚合用光照射器发出的强光照射后可迅速固化，固化体具有优异的性能，即使在高温下也能稳定保存，作为牙科复合树脂非常有用。

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