Methyl 12-(2-methoxyphenyl)aminodehydroabietate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: Methyl 12-(2-methoxyphenyl)aminodehydroabietate
• 英文别名: methyl (1R,4aS,10aR)-6-(2-methoxyanilino)-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxylate
• 化学式: C₂₈H₃₇NO₃
• 分子量: 435.607
• InChiKey: BEQIQYYFRAJTJL-BIYCFNCWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.4
• 重原子数：
  32
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  47.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  12-aminodehydroabietic acid, methyl ester 、 o-methoxyphenyllead triacetate 在 copper(I) acetate 作用下， 以 二氯甲烷 为溶剂， 反应 3.0h， 以72%的产率得到Methyl 12-(2-methoxyphenyl)aminodehydroabietate
  参考文献：
  名称：

  Synthetic Derivatives of Abietic Acid with Radical Scavenging Activity

  摘要：

  In this work, studies on the arylation of anilines derived from dehydroabietic acid, the main component of disproportionated rosin, are presented. The redox properties of the new diarylamines were investigated by cyclic voltammetry, and their free radical scavenging activity was tested by reduction of the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. Three of the diarylamines with lower oxidation potential proved to be as active as isopropyldiphenylamine (IPPD) and superior to tert-butylhydroxytoluene (BHT), both commercially available synthetic antioxidants.

  DOI：

  10.1021/np000501y

文献信息

• Synthetic Derivatives of Abietic Acid with Radical Scavenging Activity
  作者：M. Alexandra Esteves、Nama Narender、Maria J. Marcelo-Curto、Bárbara Gigante

  DOI：10.1021/np000501y

  日期：2001.6.1

  In this work, studies on the arylation of anilines derived from dehydroabietic acid, the main component of disproportionated rosin, are presented. The redox properties of the new diarylamines were investigated by cyclic voltammetry, and their free radical scavenging activity was tested by reduction of the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. Three of the diarylamines with lower oxidation potential proved to be as active as isopropyldiphenylamine (IPPD) and superior to tert-butylhydroxytoluene (BHT), both commercially available synthetic antioxidants.