(1R,2S,6R,8R)-10,10-dimethyl-5-nitro-3,7,9,11-tetraoxa-4-azatricyclo[6.3.0.02,6]undec-4-ene | 162007-84-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (1R,2S,6R,8R)-10,10-dimethyl-5-nitro-3,7,9,11-tetraoxa-4-azatricyclo[6.3.0.02,6]undec-4-ene
• CAS: 162007-84-3
• 化学式: C₈H₁₀N₂O₆
• 分子量: 230.177
• InChiKey: UJSZFJPSTNTZSU-MEOJTODESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  16
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  95.1
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  、 (1R,2S,6R,8R)-10,10-dimethyl-5-nitro-3,7,9,11-tetraoxa-4-azatricyclo[6.3.0.02,6]undec-4-ene 以46%的产率得到(1R,2S,6R,8R)-10,10-dimethyl-5-(3-phenylmethoxyprop-1-ynyl)-3,7,9,11-tetraoxa-4-azatricyclo[6.3.0.02,6]undec-4-ene
  参考文献：
  名称：

  A Useful Route to Optically Active 4-Oxygenated 4,5-Dihydroisoxazoles

  摘要：

  Optically active iodotosylates were prepared from carbohydrate precursors and were transformed by the action of excess sodium nitrite/propyl nitrite to bicyclic 4-oxygenated 4,5-dihydro-3-nitroisoxazoles.

  DOI：

  10.1021/jo00103a007
• 作为产物：
  描述：

  1,2-O-Isopropyliden-3,5-di-O-(p-tosyl)-α-D-ribofuranose 在 亚硝酸丙酯 、 sodium iodide 、 sodium nitrite 作用下， 以 二甲基亚砜 、 丁酮 为溶剂， 反应 2.0h， 生成 (1R,2S,6R,8R)-10,10-dimethyl-5-nitro-3,7,9,11-tetraoxa-4-azatricyclo[6.3.0.02,6]undec-4-ene
  参考文献：
  名称：

  A Useful Route to Optically Active 4-Oxygenated 4,5-Dihydroisoxazoles

  摘要：

  Optically active iodotosylates were prepared from carbohydrate precursors and were transformed by the action of excess sodium nitrite/propyl nitrite to bicyclic 4-oxygenated 4,5-dihydro-3-nitroisoxazoles.

  DOI：

  10.1021/jo00103a007

文献信息

• A Useful Route to Optically Active 4-Oxygenated 4,5-Dihydroisoxazoles
  作者：Peter A. Wade、Sharmila S. Shah、Lakshmi Govindarajan

  DOI：10.1021/jo00103a007

  日期：1994.12

  Optically active iodotosylates were prepared from carbohydrate precursors and were transformed by the action of excess sodium nitrite/propyl nitrite to bicyclic 4-oxygenated 4,5-dihydro-3-nitroisoxazoles.