3-carboethoxy-2,4-dichloro-5,6,7,8-tetrahydroquinoline | 132381-31-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 3-carboethoxy-2,4-dichloro-5,6,7,8-tetrahydroquinoline
• 英文别名: Ethyl 2,4-dichloro-5,6,7,8-tetrahydro-3-quinolinecarboxylate；ethyl 2,4-dichloro-5,6,7,8-tetrahydroquinoline-3-carboxylate
• CAS: 132381-31-8
• 化学式: C₁₂H₁₃Cl₂NO₂
• 分子量: 274.147
• InChiKey: VPJUUJFIRNEDGB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  39.2
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-carboethoxy-2,4-dichloro-5,6,7,8-tetrahydroquinoline 在 palladium on activated charcoal 氢气 、 magnesium oxide 作用下， 以 甲醇 为溶剂， 反应 3.0h， 以70%的产率得到5,6,7,8-四氢喹啉-3-羧酸乙酯
  参考文献：
  名称：

  Rigby, James H.; Qabar, Maher, Synthetic Communications, 1990, vol. 20, # 17, p. 2699 - 2709

  摘要：

  DOI：
• 作为产物：
  描述：

  1-isocyanatocyclohex-1-ene 在 sodium hydride 、 三氯氧磷 作用下， 以 甲苯 为溶剂， 反应 1.58h， 生成 3-carboethoxy-2,4-dichloro-5,6,7,8-tetrahydroquinoline
  参考文献：
  名称：

  Rigby, James H.; Qabar, Maher, Synthetic Communications, 1990, vol. 20, # 17, p. 2699 - 2709

  摘要：

  DOI：

文献信息

• Bicyclic fused pyridinyl amides and advantagesous compositons thereof for use as fungicides
  申请人：Bisaha Joseph John

  公开号：US20050020644A1

  公开（公告）日：2005-01-27

  Compounds of Formula I, including all geometric and stereoisomers, N-oxides, and agriculturally suitable salts thereof: (Formula I); wherein X and either Y or Z are a linking chain 3 or 4 atoms in length attached to contiguous carbon atoms and are taken together with said carbon atoms to form a fused phenyl ring, a fused 5- or 6-membered nonaromatic carbocyclic or heterocyclic ring optionally including one or two ring members selected from the group consisting of C(═O), SO or S(O) 2 , or a fused 5- or 6-membered heteroaromatic ring, each fused ring optionally substituted with one to three substituents independently selected from R 7 ; and R 1 , R 2 , R 5 , R 6 R 7 , m and p are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula I and a method for controlling plant diseases caused by fungal plant pathogens that involves applying an effective amount of a compound of Formula I.

  公式I的化合物，包括所有的几何和立体异构体，N-氧化物和适用于农业的盐：（公式I）;其中X和Y或Z之一是一个链接链，长度为3或4个原子，连接到相邻的碳原子，并与该碳原子一起形成一个融合的苯环，一个融合的5-或6-成员非芳香碳环或杂环，可选地包括来自C（═O），SO或S（O）2的一个或两个环成员，或一个融合的5-或6-成员杂芳环，每个融合环可选地被一个到三个独立选择的R7取代; R1，R2，R5，R6R7，m和p如披露中所定义。还披露了包含公式I化合物的组合物以及一种用公式I化合物的有效量来控制由真菌植物病原体引起的植物病害的方法。
• RIGBY, JAMES H.;QABAR, MAHER, SYNTH. COMMUN., 20,(1990) N7, C. 2699-2709
  作者：RIGBY, JAMES H.、QABAR, MAHER

  DOI：——

  日期：——
• BICYCLIC FUSED PYRIDINYL AMIDES AND ADVANTAGEOUS COMPOSITIONS THEREOF FOR USE AS FUNGICIDES
  申请人：E. I. du Pont de Nemours and Company

  公开号：EP1485372A2

  公开（公告）日：2004-12-15
• [EN] BICYCLIC FUSED PYRIDINYL AMIDES AND ADVANTAGEOUS COMPOSITIONS THEREOF FOR USE AS FUNGICIDES<br/>[FR] AMIDES PYRIDINYLE FUSIONNES BICYCLIQUES ET COMPOSITIONS INTERESSANTES DE CES DERNIERS UTILES EN TANT QUE FONGICIDES
  申请人：DU PONT

  公开号：WO2003080596A2

  公开（公告）日：2003-10-02

  Compounds of Formula I, including all geometric and stereoisomers, N-oxides, and agriculturally suitable salts thereof: (Formula I); wherein X and either Y or Z are a linking chain 3 or 4 atoms in length attached to contiguous carbon atoms and are taken together with said carbon atoms to form a fused phenyl ring, a fused 5- or 6-membered nonaromatic carbocyclic or heterocyclic ring optionally including one or two ring members selected from the group consisting of C(=O), SO or S(O)2, or a fused 5- or 6-membered heteroaromatic ring, each fused ring optionally substituted with one to three substituents independently selected from R7; and R1, R2, R5, R6 R7, m and p are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula I and a method for controlling plant diseases caused by fungal plant pathogens that involves applying an effective amount of a compound of Formula I.