4-[(4-Decoxyphenyl)methoxy]-2-hydroxybenzaldehyde | 150547-03-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4-[(4-Decoxyphenyl)methoxy]-2-hydroxybenzaldehyde
• CAS: 150547-03-8
• 化学式: C₂₄H₃₂O₄
• 分子量: 384.516
• InChiKey: LDUOZTOJVYXOIF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.5
• 重原子数：
  28
• 可旋转键数：
  14
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  3-氨基-1-丙醇 、 4-[(4-Decoxyphenyl)methoxy]-2-hydroxybenzaldehyde 以 乙醇 为溶剂， 反应 3.0h， 以92%的产率得到
  参考文献：
  名称：

  Smectic Bimetallomesogens: Synthesis and Mesomorphic Properties in Oxygen-Bridged Dicopper and Divanadyl Complexes

  摘要：

  AbstractThe synthesis and mesomorphic properties of a homologous series of N‐(3‐hydroxypropyl)‐4‐alkoxylsalicylaldimine, N‐(3‐hydroxypropyl)‐4‐(4′‐alkoxybenzoxy)salicylaldimine, and their dicopper(II) and di‐oxovanadium(VI) complexes are reported. Copper complexes exhibited monotropic smectic A phases; however, vanadyl complexes showed no mesomorphism. A systematic comparison revealed that the meso‐genie behaviors of these bimetallic complexes are induced by the weak intermolecular force and determined mainly by the central metal. The effects on the structural variations near the metal central cores and side chain density are also discussed.

  DOI：

  10.1002/jccs.199700014
• 作为产物：
  描述：

  p-(decyloxy)benzyl alcohol 在 氯化亚砜 、 potassium hydrogencarbonate 作用下， 以 四氢呋喃 、 丙酮 为溶剂， 反应 24.17h， 生成 4-[(4-Decoxyphenyl)methoxy]-2-hydroxybenzaldehyde
  参考文献：
  名称：

  Smectic Bimetallomesogens: Synthesis and Mesomorphic Properties in Oxygen-Bridged Dicopper and Divanadyl Complexes

  摘要：

  AbstractThe synthesis and mesomorphic properties of a homologous series of N‐(3‐hydroxypropyl)‐4‐alkoxylsalicylaldimine, N‐(3‐hydroxypropyl)‐4‐(4′‐alkoxybenzoxy)salicylaldimine, and their dicopper(II) and di‐oxovanadium(VI) complexes are reported. Copper complexes exhibited monotropic smectic A phases; however, vanadyl complexes showed no mesomorphism. A systematic comparison revealed that the meso‐genie behaviors of these bimetallic complexes are induced by the weak intermolecular force and determined mainly by the central metal. The effects on the structural variations near the metal central cores and side chain density are also discussed.

  DOI：

  10.1002/jccs.199700014

文献信息

• [EN] LIPOPHILIC AROMATIC ALDEHYDE AND KETONE DERIVATIVES AND THE USE THEREOF AS IMMUNOSTIMULANTS AND ADJUVANTS<br/>[FR] DERIVES DE CETONE ET D'ALDEHYDE AROMATIQUESLIPOPHILES ET UTILISATION DE CEUX-CI EN TANT QU'IMMUNOSTIMULANTS ET ADJUVANTS
  申请人：GALENICA PHARMACEUTICALS INC

  公开号：WO2001076626A2

  公开（公告）日：2001-10-18

  The invention in its braodest aspects relates to substituted aryl- and arylalkyl aldehyde derivatives that are useful in activating the immune system for use in prophylactic and therapeutic vaccines as well as general enhancement of the immune response. The compounds useful in this invention are broadly represented by Formula I: or a pharmaceutically acceptable salt thereof, wherein R1 through R5, and o are as defined in the specification.
• Smectic Bimetallomesogens: Synthesis and Mesomorphic Properties in Oxygen-Bridged Dicopper and Divanadyl Complexes
  作者：Yi-Fun Leu、Chung K. Lai

  DOI：10.1002/jccs.199700014

  日期：1997.4

  AbstractThe synthesis and mesomorphic properties of a homologous series of N‐(3‐hydroxypropyl)‐4‐alkoxylsalicylaldimine, N‐(3‐hydroxypropyl)‐4‐(4′‐alkoxybenzoxy)salicylaldimine, and their dicopper(II) and di‐oxovanadium(VI) complexes are reported. Copper complexes exhibited monotropic smectic A phases; however, vanadyl complexes showed no mesomorphism. A systematic comparison revealed that the meso‐genie behaviors of these bimetallic complexes are induced by the weak intermolecular force and determined mainly by the central metal. The effects on the structural variations near the metal central cores and side chain density are also discussed.