[2-(4-Tert-butylcyclohexylidene)-3-trimethylsilylpropyl]-trimethylsilane | 928796-05-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: [2-(4-Tert-butylcyclohexylidene)-3-trimethylsilylpropyl]-trimethylsilane
• 英文别名: [2-(4-tert-butylcyclohexylidene)-3-trimethylsilylpropyl]-trimethylsilane
• CAS: 928796-05-8
• 化学式: C₁₉H₄₀Si₂
• 分子量: 324.698
• InChiKey: LYDJNBUYFAXIEU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.2
• 重原子数：
  21
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  [2-(4-Tert-butylcyclohexylidene)-3-trimethylsilylpropyl]-trimethylsilane 在 4-甲基苯磺酸吡啶 作用下， 以 四氢呋喃 、 乙腈 为溶剂， 以26%的产率得到2-(4-Tert-butylcyclohexyl)prop-2-enyl-trimethylsilane
  参考文献：
  名称：

  Preparation of 2-trimethylsilylmethyl-1-alkene; cross-coupling and protodesilylation sequence from 1,1-dibromo-1-alkene

  摘要：

  A new method for the preparation of exomethylene type allylsilane is described. Selective mono-protodesilylation of 1-trimethylsityl-2-trimethylsilylmethyl-2-alkenes 2 with PPTS afforded 2-trimethylsilylmethyl-l-alkeiles 4 in excellent yields. Since the resulting allylsilanes 4 possess an exomethylene unit, the reactions of 4 with carbonyl compounds in the presence of Lewis acids gave the corresponding product 7 having an exomethylene unit in excellent yields. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2006.12.044
• 作为产物：
  描述：

  4-叔丁基环己酮 、 alkaline earth salt of/the/ methylsulfuric acid 在 palladium diacetate 、 三苯基膦 作用下， 以 四氢呋喃 、 乙醚 为溶剂， 生成 [2-(4-Tert-butylcyclohexylidene)-3-trimethylsilylpropyl]-trimethylsilane
  参考文献：
  名称：

  Preparation of 2-trimethylsilylmethyl-1-alkene; cross-coupling and protodesilylation sequence from 1,1-dibromo-1-alkene

  摘要：

  A new method for the preparation of exomethylene type allylsilane is described. Selective mono-protodesilylation of 1-trimethylsityl-2-trimethylsilylmethyl-2-alkenes 2 with PPTS afforded 2-trimethylsilylmethyl-l-alkeiles 4 in excellent yields. Since the resulting allylsilanes 4 possess an exomethylene unit, the reactions of 4 with carbonyl compounds in the presence of Lewis acids gave the corresponding product 7 having an exomethylene unit in excellent yields. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2006.12.044

文献信息

• Preparation of 2-trimethylsilylmethyl-1-alkene; cross-coupling and protodesilylation sequence from 1,1-dibromo-1-alkene
  作者：Jun’ichi Uenishi、Takuya Iwamoto、Masashi Ohmi

  DOI：10.1016/j.tetlet.2006.12.044

  日期：2007.2

  A new method for the preparation of exomethylene type allylsilane is described. Selective mono-protodesilylation of 1-trimethylsityl-2-trimethylsilylmethyl-2-alkenes 2 with PPTS afforded 2-trimethylsilylmethyl-l-alkeiles 4 in excellent yields. Since the resulting allylsilanes 4 possess an exomethylene unit, the reactions of 4 with carbonyl compounds in the presence of Lewis acids gave the corresponding product 7 having an exomethylene unit in excellent yields. (c) 2007 Elsevier Ltd. All rights reserved.