1-phenylheptane-1,5-dione | 111183-78-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-phenylheptane-1,5-dione
• CAS: 111183-78-9
• 化学式: C₁₃H₁₆O₂
• 分子量: 204.269
• InChiKey: QBWSVZLAABDSMD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-phenylheptane-1,5-dione 在 三乙基硅烷 、 三氟甲磺酸三甲基硅酯 作用下， 以 二氯甲烷 为溶剂， 反应 16.0h， 以88%的产率得到2-ethyl-6-phenyltetrahydro-2H-pyran
  参考文献：
  名称：

  通过 CC 键裂解实现的铑催化氢酰化合成 1, 5-二酮

  摘要：

  已经开发了一种铑催化的乙烯基环丁醇与非螯合醛的分子间加氢酰化反应。该反应为高产率选择性制备 1,5-二酮提供了一种新的、原子经济的方法。实验数据表明顺序开环、转移氢化和加氢酰化机制。我们建议通过形成新的铑烯醇化物物种来避免醛脱羰，这也解释了广泛的醛的相容性及其抗马尔科夫尼科夫选择性。

  DOI：

  10.1021/jacs.7b05427
• 作为产物：
  描述：

  4-苯甲酰基丁酸甲酯 在 lithium aluminium tetrahydride 、 jones reagent 、 phosphorus pentoxide 、 4-甲基苯磺酸吡啶 、 二甲基亚砜 、 三乙胺 作用下， 以 四氢呋喃 、 乙醚 、 丙酮 、 苯 为溶剂， 反应 17.0h， 生成 1-phenylheptane-1,5-dione
  参考文献：
  名称：

  Hassarajani, S. A.; Dhotare, B.; Chattopadhyay, A., Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1998, vol. 37, # 1, p. 80 - 81

  摘要：

  DOI：

文献信息

• 1,5-Dicarbonyl-Verbindungen durch Michael-Addition deprotonierter Enamine und Allylamine an 2-(<i>N</i>-Methylanilino)-acrylnitril
  作者：Hubertus Ahlbrecht、Manfred Dietz、Lothar Weber

  DOI：10.1055/s-1987-27904

  日期：——

  1,5-Dicarbonyl Compounds via Michael-Addition of Deprotonated Enamines and Allylamines to 2-(N-Methylanilino) acrylonitrile A new method for the synthesis of the title compounds by a onepot, three component, coupling reaction is described. Is consists of the reaction of a homoenolate anion and an enol cation equivalent with subsequent alkylation of an acyl-anion equivalent. Hence the methodology of Umpolung is used in a threefold manner within the reaction sequence.

  经由迈克尔加成反应合成1,5-二羰基化合物：通过去质子化的烯胺和烯丙胺对2-(N-甲基苯胺基)丙烯腈的反应。描述了一种新的合成标题化合物的一锅法、三组分偶联反应方法。该方法包括一个同烯醇盐负离子和一个烯醇正离子等价物的反应，随后是酰基负离子等价物的烷基化反应。因此，在反应序列中，极性反转策略被以三种不同的方式应用。
• Preparation and Reactions of Diorganozincs from Dienic Silyl Enol Ethers
  作者：A. Devasagayaraj、L. Schwink、P. Knochel

  DOI：10.1021/jo00116a013

  日期：1995.6

  The hydroboration of the dienic silyl enol ethers 1a-d with Et(2)BH produces organoboranes which are readily converted under mild conditions by a treatment with Et(2)Zn to the corresponding dialkylzincs 2a-d. These organometallics react after transmetalation with CuCN . 2LiCl with various electrophiles affording polyfunctional silyl enol ethers of type 4. In the presence of the chiral catalyst (1R,2R)-bis(trifluoromethanesulfonamido)cyclohexane 6, the dialkylzinc 2b was added to various aldehydes leading to hydroxy silyl enol ethers of type 8 in satisfactory yields (45-77%) and excellent enantioselectivities (85 to >96 % ee). The chiral products 8 can be oxidatively cyclized using t-BuOOH and catalytic amounts of VO(acac)(2) furnishing trisubstituted tetrahydropyrans like 9a,b with high diastereoselectivity. An iodoalkoxylation of 8 affords after HI elimination and Jones oxidation the unsaturated valerolactone 13.
• AHLBRECHT H.; DIETZ M.; WEBER L., SYNTHESIS,(1987) N 3, 251-254
  作者：AHLBRECHT H.、 DIETZ M.、 WEBER L.

  DOI：——

  日期：——
• POLISHING COMPOSITION
  申请人：FUJIMI INCORPORATED

  公开号：US20150069016A1

  公开（公告）日：2015-03-12

  There is provided a polishing composition capable of suppressing formation of a stepped portion caused by etching of a surface of a polishing object including a portion containing a group IV material when the polishing object is polished. The present invention relates to a polishing composition for polishing of a polishing object including a portion that contains a group IV material, and the polishing composition contains an oxidizing agent and an anticorrosive agent. Preferably, the anticorrosive agent includes at least one selected from the group consisting of compounds in which two or more carbonyl groups contained in a molecule are bonded through a carbon atom in the molecule. To be more specific, preferably, the anticorrosive agent includes at least one selected from the group consisting of a 1,3-diketone compound, a 1,4-diketone compound, and a triketone compound.
• US9376594B2
  申请人：——

  公开号：US9376594B2

  公开（公告）日：2016-06-28