1-(3,7-二甲基辛-6-烯-1-基)吡咯烷 | 1015422-97-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 中文名称: 1-(3,7-二甲基辛-6-烯-1-基)吡咯烷
• 英文名称: 1-(3,7-dimethyloct-6-en-1-yl)pyrrolidine
• 英文别名: N-(3,7-dimethyloct-6-en-1-yl) pyrrolidine；1-(3,7-Dimethyloct-6-enyl)pyrrolidine
• CAS: 1015422-97-5
• 化学式: C₁₄H₂₇N
• 分子量: 209.375
• InChiKey: OVXQVBJODCUQLV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  香茅醛 、 1-(3,7-二甲基辛-6-烯-1-基)吡咯烷 在 [Ru(p-cymene)(k⁽²⁾-o-tBuPPBS)Cl] 、 D(+)-10-樟脑磺酸 、 甲酸 作用下， 以 甲苯 为溶剂， 反应 19.0h， 生成 1,3-bis(3,7-dimethyloct-6-en-1-yl)pyrrolidine
  参考文献：
  名称：

  选择性碳-碳键形成：涉及氢转移的胺的萜烯化

  摘要：

  定义明确的钌（II）配合物A具有膦磺酸盐螯合物，可通过氢“自动”转移而将萜烯部分引入环状饱和胺中，而无需减少副链烯。这些生态友好的转变使生产仅用水和二氧化碳为良性副产品的各种N-和C-萜类生物碱成为可能。

  DOI：

  10.1039/c3gc36982j
• 作为产物：
  描述：

  (E)-N,N-二乙基-3,7-二甲基-2,6-辛二烯-1-胺 生成 1-(3,7-二甲基辛-6-烯-1-基)吡咯烷
  参考文献：
  名称：

  摘要：

  DOI：

文献信息

• Half-sandwich ruthenium-carbene catalysts: Synthesis, characterization, and catalytic application in the N-alkylation of amines with alcohols
  作者：Murat Kaloğlu

  DOI：10.1016/j.ica.2019.119163

  日期：2019.12

  the synthesis and characterization of new half-sandwich ruthenium complexes containing oxygen functionalised N-aryl and N-alkyl benzimidazol-2-ylidene ligands have been reported. All ruthenium complexes were tested as catalysts for a wide range of substrates in the N-alkylation of secondary cyclic amines such as pyrrolidine and piperidine, and 4-methylaniline which was a primary aromatic amine with

  摘要在这项研究中，已经报道了含有氧官能化的N-芳基和N-烷基苯并咪唑-2-亚烷基配体的新型半三明治钌络合物的合成和表征。所有的钌络合物都被用作催化剂，用于仲环胺（例如吡咯烷和哌啶）和4-甲基苯胺（它是通过醇借入醇与醇形成的芳香族伯胺）的N-烷基化反应中用于多种底物的催化剂。在无溶剂条件下，在120℃，16 h的条件下，以1 mol％的催化剂负载量进行催化反应。所有钌配合物均显示出优异的催化活性，并且选择性地获得了N-烷基化产物。
• ——
  作者：KUMOBAYASHI HIDENORI、 AKUTAGAWA SUSUMU

  DOI：——

  日期：——
• Inhibitors Of Cognitive Decline
  申请人：Rishton Gilbert M.

  公开号：US20080193574A1

  公开（公告）日：2008-08-14

  Compounds that are central nervous system drug candidates for the treatment of cognitive decline and, more particularly, Alzheimer's disease are provided. Methods of treating, inhibiting, and/or abatement of cognitive decline and Alzheimer's disease with a derivative of ginger oil are also provided. Also provided is a method of conditioning biological extracts, such as a medicinal plant extract, by a reductive amination process to give nitrogen-containing derivatives.
• Inhibitors of cognitive decline
  申请人：Rishton Gilbert M.

  公开号：US20110111068A1

  公开（公告）日：2011-05-12

  Compounds that are central nervous system drug candidates for the treatment of cognitive decline and, more particularly, Alzheimer's disease are provided. Methods of treating, inhibiting, and/or abatement of cognitive decline and Alzheimer's disease with a derivative of ginger oil are also provided. Also provided is a method of conditioning biological extracts, such as a medicinal plant extract, by a reductive amination process to give nitrogen-containing derivatives.
• US7723377B2
  申请人：——

  公开号：US7723377B2

  公开（公告）日：2010-05-25