4-[(2-methylquinolin-8-yl)imino]-4-phenylbut-2-en-2-ol | 1222487-29-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 4-[(2-methylquinolin-8-yl)imino]-4-phenylbut-2-en-2-ol
• CAS: 1222487-29-7
• 化学式: C₂₀H₁₈N₂O
• 分子量: 302.376
• InChiKey: MIDFCYCJNOIDBV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.13
• 重原子数：
  23.0
• 可旋转键数：
  3.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  45.48
• 氢给体数：
  1.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  4-[(2-methylquinolin-8-yl)imino]-4-phenylbut-2-en-2-ol 、 Mg(OBn-4-Me)2 以 四氢呋喃 为溶剂， 反应 4.0h， 以81%的产率得到bis[1-phenyl-1-(N-2-methylquinolyl)-3-butanonato]magnesium
  参考文献：
  名称：

  Synthesis and crystal structures of magnesium complexes with NNO Schiff base ligands bearing quinolyl pendant donors

  摘要：

  A series of ketoimines bearing quinolyl pendants was prepared through Schiff base condensation of 1,3-diketones (2,4-pentanedione, benzoylmethane, and 1-benzoylacetone) and 8-aminoquinoline or 8-amino-2-methylquinoline. The ketoimines were isolated in 46-90% yield and characterized spectroscopically and crystallographically. Reaction of the ketoimines with magnesium 4-methylbenzylalkoxide yielded octahedral magnesium complexes in 67-90% yield. The spectroscopic and crystallographic properties of the magnesium complexes were explored. Structures of 1, 4, 8, 10, and 11 are reported. (C) 2010 Elsevier Ltd. An rights reserved.

  DOI：

  10.1016/j.poly.2010.01.001
• 作为产物：
  描述：

  8-氨基喹哪啶 、 1-苯基-1,3-丁二酮 在 对甲苯磺酸 作用下， 以 甲苯 为溶剂， 反应 6.33h， 以57%的产率得到4-[(2-methylquinolin-8-yl)imino]-4-phenylbut-2-en-2-ol
  参考文献：
  名称：

  Synthesis and crystal structures of magnesium complexes with NNO Schiff base ligands bearing quinolyl pendant donors

  摘要：

  A series of ketoimines bearing quinolyl pendants was prepared through Schiff base condensation of 1,3-diketones (2,4-pentanedione, benzoylmethane, and 1-benzoylacetone) and 8-aminoquinoline or 8-amino-2-methylquinoline. The ketoimines were isolated in 46-90% yield and characterized spectroscopically and crystallographically. Reaction of the ketoimines with magnesium 4-methylbenzylalkoxide yielded octahedral magnesium complexes in 67-90% yield. The spectroscopic and crystallographic properties of the magnesium complexes were explored. Structures of 1, 4, 8, 10, and 11 are reported. (C) 2010 Elsevier Ltd. An rights reserved.

  DOI：

  10.1016/j.poly.2010.01.001