(5E)-4-hydroxy-6,10-dimethyl-undecane-5,9-dien-2-one | 138459-53-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (5E)-4-hydroxy-6,10-dimethyl-undecane-5,9-dien-2-one
• 英文别名: (5E)-4-hydroxy-6,10-dimethyl-undeca-5,9-dien-2-one；(5E)-4-hydroxy-6,10-dimethylundeca-5,9-dien-2-one；4-hydroxy-6,10-dimethyl-undecane-5,9-dien-2-one
• CAS: 138459-53-7
• 化学式: C₁₃H₂₂O₂
• 分子量: 210.316
• InChiKey: CUEGEJLBVIFULZ-DHZHZOJOSA-N

物化性质

• 沸点：
  340.3±30.0 °C(Predicted)
• 密度：
  0.934±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  (E)-3,7-二甲基-2,6-辛二烯醛 、 丙酮 在 sodium hydroxide 作用下， 生成 (5E)-4-hydroxy-6,10-dimethyl-undecane-5,9-dien-2-one
  参考文献：
  名称：

  Efficient aldol condensation in aqueous biphasic system under microfluidic conditions

  摘要：

  A microfluidic system was applied to aldol reaction in aqueous biphasic medium. Advantageous aspects of microfluidic conditions, that is, efficient mixing, fast heat transfer, and residence time control led to the high-yielding reaction of acetone enolate with even of-proton-containing aldehydes in biphasic aqueous-acetone system, by minimizing the formation of self-condensation products. (c) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.01.057

文献信息

• [EN] APPARATUS FOR AND PROCESS OF MAKING PSEUDOIONONE AND HYDROXY PSEUDOIONONE<br/>[FR] APPAREIL ET PROCÉDÉ DE PRODUCTION DE PSEUDOIONONE ET D'HYDROXY PSEUDOIONONE
  申请人：BASF SE

  公开号：WO2020099461A1

  公开（公告）日：2020-05-22

  The invention relates to an apparatus (1) for producing pseudoionone and hydroxy pseudoionone. It suggests an apparatus (1) comprising first and second substantially vertically oriented reactor chambers oriented such that components flow through the first and second reactor chambers in different directions, wherein the first reactor chamber (13) is configured to receive a first component feed (C1) containing a first aqueous mixture through an inlet (15), and to produce a second aqueous mixture, and wherein the apparatus (1) comprises a mixing device (17) positioned downstream of the first component feed inlet (15)and configured to add a second component feed (C2) to the first component feed (C1) when the second aqueous mixture has formed, and the second reactor chamber (23) is configured to receive the first and second component feeds unified in the mixing device (17) from the first reactor chamber (13) and to produce a third aqueous mixture from the first and second aqueous mixtures. The invention further suggests a method and a use for producing pseudoionone and hydroxy pseudoionone.

  该发明涉及一种用于生产伪紫罗兰酮和羟基伪紫罗兰酮的装置（1）。它提出了一种装置（1），包括第一和第二基本垂直定向的反应器室，使得组分通过第一和第二反应器室以不同方向流动，其中第一反应器室（13）被配置为通过入口（15）接收含有第一水混合物的第一组分进料（C1），并产生第二水混合物，该装置（1）包括一个混合装置（17），位于第一组分进料入口（15）的下游，并且在第二水混合物形成时配置为向第一组分进料（C1）添加第二组分进料（C2），第二反应器室（23）被配置为从第一反应器室（13）接收在混合装置（17）中统一的第一和第二组分进料，并从第一和第二水混合物中产生第三水混合物。该发明进一步提出了一种用于生产伪紫罗兰酮和羟基伪紫罗兰酮的方法和用途。
• [EN] PROCESS OF MAKING PSEUDOIONONE AND HYDROXY PSEUDOIONONE IN AQUEOUS MIXTURES COMPRISING CITRAL AND ACETONE, COMPRISING ADDING FIRST AND SECOND AMOUNTS OF HYDROXIDE<br/>[FR] PROCÉDÉ DE FABRICATION DE PSEUDOIONONE ET D'HYDROXY PSEUDOIONONE DANS DES MÉLANGES AQUEUX CONTENANT DU CITRAL ET DE L'ACÉTONE, COMPRENANT L'AJOUT DE PREMIÈRE ET SECONDE QUANTITÉS D'HYDROXYDE
  申请人：BASF SE

  公开号：WO2020099452A1

  公开（公告）日：2020-05-22

  Described is a process of making pseudoionone and hydroxy pseudoionone comprising the steps of (i) preparing a first aqueous mixture comprising first concentrations of acetone, citral and hydroxide, (ii) producing a second aqueous mixture by allowing to react for a reaction time the components of the first aqueous mixture and (iii) producing a third aqueous mixture by adding to the second aqueous mixture a second amount of hydroxide so that an additional amount of pseudoionone is formed in the third aqueous mixture. The invention further suggests an apparatus for making pseudoionone and hydroxy pseudoionone as well as to a respective process and use of said apparatus in making pseudoionone and hydroxy pseudoionone.

  描述了一种制备伪离子酮和羟基伪离子酮的过程，包括以下步骤：(i) 准备含有丙酮、柠檬醛和氢氧化物的第一水混合物，(ii) 通过让第一水混合物的组分在反应时间内发生反应来生成第二水混合物，(iii) 向第二水混合物中添加第二量氢氧化物，以使第三水混合物中形成额外的伪离子酮。该发明进一步提出了一种用于制备伪离子酮和羟基伪离子酮的装置，以及在制备伪离子酮和羟基伪离子酮中使用该装置的相应过程和用途。
• Process of making pseudoionone and hydroxy pseudoionone in aqueous mixtures comprising citral and acetone, comprising adding first and second amounts of hydroxide
  申请人：BASF SE

  公开号：US11396487B2

  公开（公告）日：2022-07-26

  Described is a process of making pseudoionone and hydroxy pseudoionone comprising the steps of (i) preparing a first aqueous mixture comprising first concentrations of acetone, citral and hydroxide, (ii) producing a second aqueous mixture by allowing to react for a reaction time the components of the first aqueous mixture and (iii) producing a third aqueous mixture by adding to the second aqueous mixture a second amount of hydroxide so that an additional amount of pseudoionone is formed in the third aqueous mixture. The invention further suggests an apparatus for making pseudoionone and hydroxy pseudoionone as well as to a respective process and use of said apparatus in making pseudoionone and hydroxy pseudoionone.

  本发明描述了一种制造假葱头酮和羟基假葱头酮的工艺，包括以下步骤：(i) 制备由第一浓度的丙酮、柠檬醛和氢氧化物组成的第一水性混合物；(ii) 使第一水性混合物中的各组分在一定反应时间内发生反应，生成第二水性混合物；(iii) 向第二水性混合物中加入第二量的氢氧化物，生成第三水性混合物，从而在第三水性混合物中形成额外量的假葱头酮。本发明进一步提出了一种用于制造假壬酮和羟基假壬酮的设备，以及制造假壬酮和羟基假壬酮的相应工艺和所述设备的用途。
• APPARATUS FOR AND PROCESS OF MAKING PSEUDOIONONE AND HYDROXY PSEUDOIONONE
  申请人：BASF SE

  公开号：EP3880638A1

  公开（公告）日：2021-09-22
• PROCESS OF MAKING PSEUDOIONONE AND HYDROXY PSEUDOIONONE IN AQUEOUS MIXTURES COMPRISING CITRAL AND ACETONE, COMPRISING ADDING FIRST AND SECOND AMOUNTS OF HYDROXIDE
  申请人：BASF SE

  公开号：EP3880639A1

  公开（公告）日：2021-09-22