(+/-)-2endo-phenylcarbamoyl-norbornane-carboxylic acid-(3endo)

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (+/-)-2endo-phenylcarbamoyl-norbornane-carboxylic acid-(3endo)
• 英文别名: (+/-)-2endo-Phenylcarbamoyl-norbornan-carbonsaeure-(3endo)；(1S,2S,3R,4R)-3-(phenylcarbamoyl)bicyclo[2.2.1]heptane-2-carboxylic acid
• 化学式: C₁₅H₁₇NO₃
• 分子量: 259.305
• InChiKey: GIEVPAJFDYLFCM-DNIRFERGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  66.4
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  乙醇 、 (+/-)-2endo-phenylcarbamoyl-norbornane-carboxylic acid-(3endo) 生成 alkaline earth salt of/the/ methylsulfuric acid
  参考文献：
  名称：

  Null Mutation in Puroindoline A is Prevalent in Indian Wheats: Puroindoline Genes are Located in The Distal Part of 5DS

  摘要：

  PCR amplification and protein analysis of pinA and pinB, the two components of friabilin, a marker protein for grain softness, were carried out in one hundred varieties from India and forty varieties from Kansas State, USA. Glycine to serine change in pinB or null mutation in pinA (absence of gene) has been reported linked with grain hardness. Here we report that majority of Kansas State hard wheats possess glycine to serine mutation in pinB and few have null mutation in pinA. In contrast, majority of varieties released in India are hard and have null mutation in pinA. There are some exceptions where some hard wheats in India do not exhibit either null mutation in pinA or glycine to serine change in pinB. There might be some additional mutations that are to be characterised in elucidating the molecular basis of hardness for usage in genetic engineering. PinA and pinB genes have been assigned on the distal part of 5D short arm using deletion lines of chinese spring wheat where hardness gene Ha is reported to be present.

  DOI：

  10.1007/bf03263140
• 作为产物：
  描述：

  3,6-endomethylene-1,2,3,6-tetrahydrophthalic anhydride 在 1,4-二氧六环 、 氯仿 、 镍 作用下， 生成 (+/-)-2endo-phenylcarbamoyl-norbornane-carboxylic acid-(3endo)
  参考文献：
  名称：

  Null Mutation in Puroindoline A is Prevalent in Indian Wheats: Puroindoline Genes are Located in The Distal Part of 5DS

  摘要：

  PCR amplification and protein analysis of pinA and pinB, the two components of friabilin, a marker protein for grain softness, were carried out in one hundred varieties from India and forty varieties from Kansas State, USA. Glycine to serine change in pinB or null mutation in pinA (absence of gene) has been reported linked with grain hardness. Here we report that majority of Kansas State hard wheats possess glycine to serine mutation in pinB and few have null mutation in pinA. In contrast, majority of varieties released in India are hard and have null mutation in pinA. There are some exceptions where some hard wheats in India do not exhibit either null mutation in pinA or glycine to serine change in pinB. There might be some additional mutations that are to be characterised in elucidating the molecular basis of hardness for usage in genetic engineering. PinA and pinB genes have been assigned on the distal part of 5D short arm using deletion lines of chinese spring wheat where hardness gene Ha is reported to be present.

  DOI：

  10.1007/bf03263140

文献信息

• Null Mutation in Puroindoline A is Prevalent in Indian Wheats: Puroindoline Genes are Located in The Distal Part of 5DS
  作者：Sewa Ram、E. Boyko、M. J. Giroux、B. S. Gill

  DOI：10.1007/bf03263140

  日期：2002.7

  PCR amplification and protein analysis of pinA and pinB, the two components of friabilin, a marker protein for grain softness, were carried out in one hundred varieties from India and forty varieties from Kansas State, USA. Glycine to serine change in pinB or null mutation in pinA (absence of gene) has been reported linked with grain hardness. Here we report that majority of Kansas State hard wheats possess glycine to serine mutation in pinB and few have null mutation in pinA. In contrast, majority of varieties released in India are hard and have null mutation in pinA. There are some exceptions where some hard wheats in India do not exhibit either null mutation in pinA or glycine to serine change in pinB. There might be some additional mutations that are to be characterised in elucidating the molecular basis of hardness for usage in genetic engineering. PinA and pinB genes have been assigned on the distal part of 5D short arm using deletion lines of chinese spring wheat where hardness gene Ha is reported to be present.