2,7-二氨基菲-9,10-二酮 | 49546-41-0

• 物质功能分类: 化学试剂 - 有机试剂 - 多环化合物
• 分子结构分类: 有机化合物 - 苯类化合物 - 菲及其衍生物
• 中文名称: 2,7-二氨基菲-9,10-二酮
• 英文名称: 2,7-diamino-phenanthrene-9,10-dione
• 英文别名: 2,7-Diamino-9,10-phenanthrenchinon；2,7-amino-9,10 phenanthrenequinone；2,7-diamino-9,10-phenanthrenequinone；2,7-Diamino-phenanthren-9,10-dion；2.7-Diamino-phenanthren-chinon-(9.10)；2,7-Diaminophenanthrene-9,10-dione
• CAS: 49546-41-0
• 化学式: C₁₄H₁₀N₂O₂
• 分子量: 238.246
• InChiKey: FIPYLFQPDJPOKA-UHFFFAOYSA-N

物化性质

• 熔点：
  >360 °C(Solv: ethanol (64-17-5))
• 沸点：
  577.9±43.0 °C(Predicted)
• 密度：
  1.456±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  18
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  86.2
• 氢给体数：
  2
• 氢受体数：
  4

安全信息

• 危险性防范说明：
  P264,P280,P302+P352,P337+P313,P305+P351+P338,P362+P364,P332+P313
• 危险性描述：
  H315,H319

反应信息

• 作为反应物：
  描述：

  2,7-二氨基菲-9,10-二酮 以 N,N-二甲基甲酰胺 、 丙酮 为溶剂， 反应 5.5h， 生成 2,7-Bis<(diethylamino)acetylamino>-9,10-phenanthrenchinon
  参考文献：
  名称：

  Hoffmann, Siegfried; Skoelziger, Regina; Witkowski, Werner, Zeitschrift fur Chemie, 1985, vol. 25, # 12, p. 433 - 434

  摘要：

  DOI：
• 作为产物：
  描述：

  2,7-diamino-phenanthrene-9,10-diol 在 三氯化铁 作用下， 生成 2,7-二氨基菲-9,10-二酮
  参考文献：
  名称：

  Kleemann; Wense, Chemische Berichte, 1885, vol. 18, p. 2168

  摘要：

  DOI：

文献信息

• Electrophotographic photoconductor, process for forming an image, image forming apparatus and a process cartridge for the same
  申请人：——

  公开号：US20030190540A1

  公开（公告）日：2003-10-09

  Providing an electrophotographic photoconductor comprising a conductive support and a photoconductive layer disposed on the photoconductive support; wherein the photoconductive layer contains an azo compound expressed by a general formula <<1>>. Ar &Parenopenst;N═N—Cp) n general formula <<1>> (in the general formula <<1>>, Ar expresses one of a substituted or non-substituted aromatic carbon hydride group and heterocyclic ring aromatic series group which can be combined by way of a bond group; Cp expresses a coupler residual group; n expresses an integer of one of 1, 2, 3, and 4; at least one of the Cp is a coupler residual group selected from one of the following general formulae <<2>>, <<3>>, and <<4>>.) 1

  提供一种电照相光导体，包括导电支持和设置在光导支承上的光导层；其中，所述光导层含有一种由下式表示的偶氮化合物。
• Cd45 inhibitors
  申请人：——

  公开号：US20030207812A1

  公开（公告）日：2003-11-06

  Substituted phenanthrene-9,10-diones in accord with structural diagram I, 1 compositions thereof and methods for the use thereof, for the treatment of T cell mediated conditions such as autoimmune diseases and organ graft rejection. In compounds of the invention, R 1 at each occurrence is independently selected from hydrogen, halogen, NH-tosyl, N-di-tosyl, NH 2 , NO 2 , NH—CO—R 2 , CO—NH—R 2 , Ar, (CH 2 ) n CH(COOH)R 3 COR 3 and NHCOCH 2 CH(COOH)NHR 4 , where R 2 , R 3 and R 4 are a selected from a variety of substituted or unsubstituted alkyl and aryl groupstand oligopeptides.

  根据结构图I，以及其中的苯并蒽-9,10-二酮，其组成物和使用方法，用于治疗T细胞介导的情况，如自身免疫疾病和器官移植排斥。在本发明的化合物中，每个出现的R1独立地选自氢、卤素、NH-对甲苯磺酰基、N-二对甲苯磺酰基、NH2、NO2、NH-CO-R2、CO-NH-R2、Ar、(CH2)nCH(COOH)R3COR3和NHCOCH2CH(COOH)NHR4，其中R2、R3和R4选自各种取代或未取代的烷基和芳基以及寡肽。
• [EN] COMPOSITIONS AND METHODS OF MAKING EXPANDED HEMATOPOIETIC STEM CELLS USING PTEN INHIBITORS<br/>[FR] COMPOSITIONS ET MÉTHODES DE PRODUCTION DE CELLULES SOUCHES HÉMATOPOÏÉTIQUES EXPANSÉES À L'AIDE D'INHIBITEURS DE PTEN
  申请人：TRANSFUSION HEALTH LLC

  公开号：WO2018217567A1

  公开（公告）日：2018-11-29

  This invention is directed to, inter alia, compounds, methods, systems, and compositions for the maintenance, enhancement, and expansion of hematopoietic stem cells derived from sources of non-mobilized peripheral blood. Also provided herein are compounds of Formula I which are useful in maintaining, enhancing, and expanding of hematopoietic stem cells.

  本发明涉及一些方面，包括用于维持、增强和扩展非动员周围血源造血干细胞的化合物、方法、系统和组合物。本文还提供了一些公式I的化合物，这些化合物可用于维持、增强和扩展造血干细胞。
• Electrophotographic photoconductor, process for forming an image, image forming apparatus and process cartridge for the same
  申请人：Shoshi Masayuki

  公开号：US20050112487A1

  公开（公告）日：2005-05-26

  Providing an electrophotographic photoconductor comprising a conductive support and a photoconductive layer disposed on the photoconductive support; wherein the photoconductive layer contains an azo compound expressed by a general formula <<1>>. ArN═N—Cp) n general formula <<1>> (in the general formula <<1>>, Ar expresses one of a substituted or non-substituted aromatic carbon hydride group and heterocyclic ring aromatic series group which can be combined by way of a bond group; Cp expresses a coupler residual group; n expresses an integer of one of 1, 2, 3, and 4; at least one of the Cp is a coupler residual group selected from one of the following general formulae <<2>>, <<3>>, and <<4>>.)

  提供一种电子照相感光鼓，包括一个导电支撑和一个位于导电支撑上的感光层；其中，感光层包含一个由一般式<<1>>表示的偶氮化合物。一般式<<1>>为：ArN═N—Cp)n（在一般式<<1>>中，Ar表示取代或未取代的芳香碳氢基团和杂环芳香系列基团之一，可以通过键基团结合；Cp表示偶合剩余基团；n表示1、2、3和4中的一个整数；Cp中至少有一个是从以下一般式<<2>>、<<3>>和<<4>>中选择的偶合剩余基团之一）。
• Process for production of vinyl chloride polymer
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：EP0172427A2

  公开（公告）日：1986-02-26

  This process is a process for production of a vinyl chloride polymer by suspension polymerization or emulsion polymerization of vinyl chloride monomer or a mixture of vinyl chloride monomer with a vinyl monomer copolymerizable with said vinyl chloride monomer in an aqueous medium, characterized in that the polymerization is carried out in a polymerizer, the inner wall surface and portions of the auxiliary equipment thereof which may come into contact with the monomer during polymerization being previously coated with a scaling preventive comprising at least one selected from dyes, pigments and aromatic or heterocyclic compounds having at least 5 conjugated π bonds, while controlling the chloride ion concentration in the reaction mixture to not higher than 100 ppm. According to said process, scaling onto the inner wall surface of a polymerizer, etc. during polymerization can be prevented effectively and surely.

  该工艺是通过氯乙烯单体或氯乙烯单体与可与所述氯乙烯单体共聚的乙烯基单体混合物在水介质中进行悬浮聚合或乳液聚合来生产氯乙烯聚合物的工艺，其特征在于聚合是在聚合器中进行的、内壁表面及其辅助设备中可能在聚合过程中与单体接触的部分事先涂上一层防垢剂，该防垢剂至少包括一种选自染料、颜料和至少有 5 个共轭 π 键的芳香族或杂环化合物的防垢剂，同时控制反应混合物中的氯离子浓度不高于 100 ppm。根据上述工艺，可有效、可靠地防止聚合过程中聚合器等内壁表面结垢。