dihydro-α-ionone | 98633-46-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: dihydro-α-ionone
• 英文别名: dihydro alpha ionone；dihydroionone；irone；5,6-Dihydro-β-ionon；4-(2,2,6-Trimethylcyclohexyl)-3-buten-2-one；(E)-4-(2,2,6-trimethylcyclohexyl)but-3-en-2-one
• CAS: 98633-46-6
• 化学式: C₁₃H₂₂O
• 分子量: 194.317
• InChiKey: YJRODKCOICMRBO-BQYQJAHWSA-N

物化性质

• 沸点：
  265.3±9.0 °C(Predicted)
• 密度：
  0.906±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.77
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  dihydro-α-ionone 在 二氯二茂钛 正丁基锂 、 Isobutylmagnesium chloride 、 氯磷酸二乙酯 、 lithium diisopropyl amide 作用下， 生成 (E)-4-Hydroxy-2-[(E)-2-(2,2,6-trimethyl-cyclohexyl)-vinyl]-but-2-enoic acid
  参考文献：
  名称：

  Synthesis of a new phospholipase A2inhibitor of an aldehyde terpenoid and its possible inhibitory mechanism

  摘要：

  3-(E)-Methoxycarbonyl-2,4,6-trienal compound A was stereoselectively synthesized and found to show strong inhibitory activity toward phospholipase A(2) (PLA(2)) from bovine pancreas. As the inhibitory mechanism of PLA(2) by A, the irreversible formation of dihydropyridine resulting from the reaction of A with lysine residues in PLA(2) is proposed based on the model reactions. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(97)10805-x
• 作为产物：
  描述：

  2,2,6-三甲基环己酮 在 氢氧化钾 、 甲酸 作用下， 以 甲醇 为溶剂， 反应 8.0h， 生成 dihydro-α-ionone
  参考文献：
  名称：

  de Botton,M., Bulletin de la Societe Chimique de France, 1966, p. 2212 - 2217

  摘要：

  DOI：

文献信息

• Process for Conducting an Organic Reaction in Ionic Liquids
  申请人：Bourgeois Daniel Martin

  公开号：US20110152566A1

  公开（公告）日：2011-06-23

  The present disclosure describes processes for producing cyclohexenes using Lewis acidic ionic liquids comprising the steps of providing to a reactor an α,β-unsaturated carbonyl dienophile, providing to the reactor a 1,3-diene, providing a Lewis acidic ionic liquid to the reactor; and reacting the α,β-unsaturated carbonyl dienophile with 1,3-diene to form a substituted cyclohexene product. The α,β-unsaturated carbonyl dienophile can be mesityl oxide, the 1,3-diene can be piperylene; and the Lewis acidic ionic liquid can be AlCl 3 :[C 2 mim]Cl; AlCl 3 :[C 8 mim]Cl; or mixtures thereof.

  本公开描述了使用含有Lewis酸性离子液体的方法生产环己烯的过程，包括向反应器提供α，β-不饱和羰基二烯亲受体，向反应器提供1,3-二烯，向反应器提供Lewis酸性离子液体；并将α，β-不饱和羰基二烯亲受体与1,3-二烯反应以形成取代环己烯产物。α，β-不饱和羰基二烯亲受体可以是甲苯酮氧，1,3-二烯可以是戊二烯；Lewis酸性离子液体可以是AlCl3:[C2mim]Cl；AlCl3:[C8mim]Cl；或它们的混合物。
• A convenient, efficient method for conjugate reductions using catalytic quantities of Cu(I)
  作者：Bruce H. Lipshutz、John Keith、Patrick Papa、Randall Vivian

  DOI：10.1016/s0040-4039(98)00855-7

  日期：1998.6

  Exposure of enones and enals to either Bu3SnH or PhSiH3 in the presence of ≤ 5 mol % [(Ph3P)CuH]6 leads to products of 1,4-hydride delivery in good yields.

  在≤5摩尔％[（Ph 3 P）CuH] 6的存在下，将烯酮和烯酮暴露于Bu 3 SnH或PhSiHH 3可以高产率地递送1,4-氢化物。
• Halogen containing ionone derivatives and compositions containing same
  申请人：Fritzsche Dodge & Olcott Inc.

  公开号：US04272412A1

  公开（公告）日：1981-06-09

  The present invention relates to novel compounds useful as fragrance materials which have the structure ##STR1## wherein the dashed line may be either a carbon-carbon single bond or a carbon-carbon double bond; R.sub.1, R.sub.2 and R.sub.3 are each the same or different and each represents hydrogen or methyl; and X is halogen. The invention also provides methods of preparing these compounds from readily available cyclohexene derivatives and fragrance compositions which include the compounds.

  本发明涉及作为香料材料有用的新化合物，其具有以下结构##STR1##其中虚线可以是碳-碳单键或碳-碳双键；R.sub.1、R.sub.2和R.sub.3分别相同或不同，每个代表氢或甲基；X为卤素。该发明还提供了从易得的环己烯衍生物制备这些化合物的方法以及包括这些化合物的香料组合物。
• Ambrinol and its homologues
  申请人：Fritzsche Dodge & Olcott Inc.

  公开号：US04341908A1

  公开（公告）日：1982-07-27

  Compounds useful as fragrance materials having the structure ##STR1## wherein each of R.sub.1, R.sub.2, and R.sub.3 are hydrogen or methyl can be prepared by reacting a halogen-containing cyclohexane, having the structure ##STR2## wherein each of R.sub.1, R.sub.2, and R.sub.3 are hydrogen or methyl and X is a halogen, with a reagent capable of effecting intramolecular cyclization.

  具有结构##STR1##的化合物可用作香料材料，其中R.sub.1、R.sub.2和R.sub.3中的每一个都是氢或甲基，可以通过将具有结构##STR2##的含卤代环己烷与能够引发分子内环化的试剂反应来制备。
• Napthofuran derivatives useful in odorant and flavorant compositions and
  申请人：Givaudan-Roure Corporation

  公开号：US05416069A1

  公开（公告）日：1995-05-16

  Novel naphthofuran derivatives of the formula ##STR1## wherein R represents hydrogen, methyl or ethyl. The compounds of formula I are valuable (amber) odorants and also flavorants. Odorant and flavorant compositions employing (I) as well as processes for making them are also described.

  新的萘呋喃衍生物的结构式为##STR1##其中R代表氢、甲基或乙基。式I的化合物是有价值的（琥珀）香料，也是调味剂。还描述了使用(I)的香料和调味剂组合物，以及制备它们的方法。