全氟甲基环戊烷 | 1805-22-7

• 物质功能分类: 有机原料 - 烃类化合物及其衍生物 - 环烃
• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氟化物
• 中文名称: 全氟甲基环戊烷
• 英文名称: perfluoro(2-methylcyclopentane)
• 英文别名: perfluoro (methylcyclopentane)；perfluoro-(methylcyclopentane)；perfluoro(methylcyclopentane)；perfluoromethylcyclopentane；Nonafluoro(trifluoromethyl)cyclopentane；Dodecafluor-methylcyclopentan；1,1,2,2,3,3,4,4,5-nonafluoro-5-(trifluoromethyl)cyclopentane
• CAS: 1805-22-7
• 化学式: C₆F₁₂
• 分子量: 300.047
• InChiKey: BCNXQFASJTYKDJ-UHFFFAOYSA-N

物化性质

• 熔点：
  45 °C
• 沸点：
  48 °C
• 密度：
  1.707
• LogP：
  666 at 25℃

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  18
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  12

安全信息

• 危险品标志：
  Xi
• 危险类别码：
  R22
• 海关编码：
  2903890090
• 安全说明：
  S23
• WGK Germany：
  3

反应信息

• 作为反应物：
  描述：

  全氟甲基环戊烷 在 四丁基碘化铵 作用下， 以 四氢呋喃 为溶剂， 生成 1,3,3,4,4,5,5-七氟-2-(三氟甲基)环戊烯
  参考文献：
  名称：

  Functionalization of saturated fluorocarbons

  摘要：

  A method is described for transforming perfluoroalkanes and perfluorocycloalkanes bearing tertiary fluorine into perfluoroenolates, which can be variously derivatized. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(99)01312-x
• 作为产物：
  描述：

  bis(perfluorocyclohexyl)difluoromethane 生成 全氟甲基环戊烷
  参考文献：
  名称：

  The pyrolytic reactions of perfluoroisopropylcyclohexane and of some perfluorodicyclohexyl alkanes

  摘要：

  DOI：

  10.1016/s0040-4020(01)99131-8

文献信息

• [EN] GEL FORMULATIONS FOR ENHANCING THE EFFECT OF RADIOTHERAPY<br/>[FR] FORMULATIONS DE GEL POUR AMÉLIORER L'EFFET DE RADIOTHÉRAPIE
  申请人：UNIV DENMARK TECH DTU

  公开号：WO2016079331A1

  公开（公告）日：2016-05-26

  The present invention relates to a composition comprising: a. non-water soluble carbohydrates b. a contrast agent for imaging, wherein at least 60% of the contrast agent remains within 10 cm from the injection site after 24h, for use in local co-administration into a human or animal body, and wherein the composition is a liquid before administration into the human or animal body and increases in viscosity by more than 1,000 centipoise (cP) after administration.

  本发明涉及一种包含以下成分的组成物：a. 非水溶性碳水化合物 b. 成像的对比剂，其中至少60%的对比剂在24小时后保持在注射部位10厘米范围内，用于在人体或动物体内局部共同给药，并且该组成物在给药前为液态，在给药后在粘度上增加超过1,000厘泊（cP）。
• COSMETIC OIL-IN-WATER EMULSION
  申请人：LORANT Raluca

  公开号：US20090105353A1

  公开（公告）日：2009-04-23

  A cosmetic or dermatological compositions of oil-in-water emulsion type, including, in a physiologically acceptable medium, at least gemini surfactant of formula (I): in which R 1 and R 3 denote, independently of one another, an alkyl radical containing from 1 to 25 carbon atoms; R 2 denotes a spacer consisting of a linear or branched alkylene chain containing from 1 to 12 carbon atoms; X and Y denote, independently of one another, a group —(C 2 H 4 O) a —(C 3 H 6 O) b Z; n ranges from 1 to 10, in combination with an effective amount of at least one semi-crystalline polymer which is solid at ambient temperature and which has a melting point below 70° C., said polymer having a number-average molecular mass greater than or equal to 2000, said emulsion having a proportion of fatty phase of greater than 10% by weight relative to the total weight of the composition and including more than 40% by weight of non-volatile oil(s) relative to the weight of the fatty phase.

  一种油包水乳液型的化妆品或皮肤科学组合物，包括在生理上可接受的介质中，至少含有式(I)的双胞胜肽表面活性剂： 其中R1和R3分别独立地表示含有1至25个碳原子的烷基基团；R2表示由含有1至12个碳原子的线性或支链烷基链组成的间隔物；X和Y分别独立地表示一个基团—(C2H4O)a—(C3H6O)bZ；n的范围为1至10，结合有效量的至少一种半结晶聚合物，该聚合物在常温下为固体且熔点低于70°C，所述聚合物的数均分子质量大于或等于2000，所述乳液具有相对于组合物的总重量大于10%的脂肪相比例，并且相对于脂肪相的重量包含超过40%的非挥发性油。
• Electrochemical fluorination of several esters derived from oxolane-2-yl-carboxylic acid, oxolane-2-yl-methanol and oxane-2-yl-methanol
  作者：Takashi Abe、Masanori Tamura、Akira Sekiya

  DOI：10.1016/j.jfluchem.2004.11.014

  日期：2005.3

  Electrochemical fluorination (ECF) of the ester derivatives of oxolane-2-yl-carboxylic acid (1), oxolane-2-yl-methanol (2) and oxane-2-yl-methanol (3) were investigated. Perfluoro(oxolane-2-yl-carbonylfluoride) (4) was obtained from derivatives of 1 and 2, and perfluoro(oxane-2-yl-carbonylfluoride) (5) was obtained from derivatives of 3 as the desired compounds, respectively. From the ECF of acetates

  研究了环氧乙烷-2-基-羧酸（1），环氧乙烷-2-基-甲醇（2）和环氧烷-2-基-甲醇（3）的酯衍生物的电化学氟化（ECF）。全氟（氧杂环戊烷-2-基- carbonylfluoride）（4）从的衍生物获得的1和2，和全氟（氧杂环己烷-2-基- carbonylfluoride）（5从衍生物获得）3作为所需化合物，分别。从2和3的乙酸盐的ECF，还以低收率获得了具有二氧戊环环的全氟螺醚与所需的全氟酰氟（4和5）。通过分析通过与AlCl 3反应获得的氯化产物，证实了这些全氟螺醚的结构。
• MAKEUP COMPOSITION
  申请人：KERGOSIEN Guillaume

  公开号：US20110150805A1

  公开（公告）日：2011-06-23

  Composition for making up keratin fibres, such as eyelashes or eyebrows, having improved makeup-removing properties, containing in a continuous aqueous phase: an aqueous dispersion of a particular polyurethane present in an amount of solids greater than or equal to 5% by weight relative to the total weight of said composition, and said composition comprising an emulsifying system comprising less than 2% by weight of triethanolamine.

  用于制造角蛋白纤维（如睫毛或眉毛）的组合物，具有改善卸妆性能，包含在连续水相中：特定聚氨酯的水分散体，其含量固体物质量大于或等于所述组合物总重量的5%，以及所述组合物包括含有少于2%三乙醇胺的乳化系统。
• [EN] GEL FORMULATIONS FOR IMPROVING IMMUNOTHERAPY<br/>[FR] FORMULATIONS DE GEL PERMETTANT D'AMÉLIORER L'IMMUNOTHÉRAPIE
  申请人：UNIV DENMARK TECH DTU

  公开号：WO2016079332A1

  公开（公告）日：2016-05-26

  The present invention relates to a composition for use as controlled release of at least one active pharmaceutical ingredient that modulates an immunogenic response in a human or animal body, said composition comprising non-water soluble carbohydrates and wherein the composition is a liquid before administration into the human or animal body and increases in viscosity by more than 1,000 centipoise (cP) after administration.

  本发明涉及一种用作控制释放至少一种活性药物成分的组合物，该活性药物成分调节人体或动物体内的免疫应答，所述组合物包括非水溶性碳水化合物，并且在进入人体或动物体内之前是液体，在给药后粘度增加超过1,000厘泊（cP）。