2-碘-1,3-丙二醇 | 5349-29-1

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 卤代醇
• 中文名称: 2-碘-1,3-丙二醇
• 英文名称: 2-iodo-1,3-propanediol
• 英文别名: 2-iodo-propane-1,3-diol；2-Jod-propan-1,3-diol；Glycerin-2-jodhydrin；Glycerin-β-jodhydrin；2-Jod-1.3-dihydroxy-propan；glycerol β-iodohydrin；2-Iodopropane-1,3-diol
• CAS: 5349-29-1
• 化学式: C₃H₇IO₂
• 分子量: 201.992
• InChiKey: UQTRRWUQXIOVPL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  6
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-碘-1,3-丙二醇 、 雄诺龙 在 对甲苯磺酸 作用下， 以 苯 为溶剂， 生成
  参考文献：
  名称：

  Free radical macrocyclizations from steroid-derived precursors

  摘要：

  Stereoselective free radical addition reactions were studied using steroid-derived templates in an attempt to control product dispersity. Templates were prepared from bifunctional steroids appropriately substituted with initiating and terminating functionality. Free radical initiation in the presence of a polymerizable olefin resulted in the formation of macrocycles that had incorporated monomer. The yield of macrocycle formed was as high as 51 % for templates derived from lithocholic acid whereas templates derived from androstanolone failed to give significant amounts of macrocycles. The effects of variation of initiating and terminating functionality, steroid, and olefin on macrocycle size and yield were examined.

  DOI：

  10.1021/jo00057a034
• 作为产物：
  描述：

  2-氯-1,3-丙二醇 在 丙酮 、 sodium iodide 作用下， 生成 2-碘-1,3-丙二醇
  参考文献：
  名称：

  The C₄-Saccharinic Acids. VI. Further Attempts to Prepare 2,2'-Dihydroxyisobutyric Acid. 2,3-Dihydroxybutyric Acid Lactone from Glycidol. The Preparation of the Two Iodohydrins of Glycerol¹

  摘要：

  DOI：

  10.1021/ja01330a041

文献信息

• Structure-activity relationship of lipopeptide from outer membrane of Escherichia coli and synthesis of highly immunopotenting lipopeptide derivatives with an achiral lipo-part.
  作者：Muneaki KURIMURA、Kazuo ACHIWA

  DOI：10.1248/cpb.41.627

  日期：——

  For outstanding the structere-activity relationship of lipopeptide derivatives, high biologically active lipopeptide derivatives with an achiral lipo-part were newly synthesized

  为了突出脂肽衍生物的结构-活性关系，新近合成了具有非手性脂部分的生物活性高的脂肽衍生物。
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  作者：Verkade,P.E.

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