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正十二烷基-alpha-D-麦芽糖苷 | 116183-64-3

中文名称
正十二烷基-alpha-D-麦芽糖苷
中文别名
正十二烷基-α-D-麦芽糖苷;正十二烷基-Α-D-麦芽糖苷
英文名称
n-dodecyl α-D-glucopyranosyl-(1->4)-α-D-glucopyranoside
英文别名
n-dodecyl 4-O-α-D-glucopyranosyl-α-D-glucopyranoside;n-dodecyl-β-D-maltopyranoside;n-dodecyl-α(1-4) maltoside;n-dodecyl α-D-maltoside;dodecyl α-D-maltoside;lauryl α-D-maltoside;Dodecyl-alpha-D-maltoside;(2R,3R,4S,5S,6R)-2-[(2R,3S,4R,5R,6S)-6-dodecoxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
正十二烷基-alpha-D-麦芽糖苷化学式
CAS
116183-64-3
化学式
C24H46O11
mdl
——
分子量
510.623
InChiKey
NLEBIOOXCVAHBD-YHBSTRCHSA-N
BEILSTEIN
——
EINECS
——
  • 物化性质
  • 计算性质
  • ADMET
  • 安全信息
  • SDS
  • 制备方法与用途
  • 上下游信息
  • 反应信息
  • 文献信息
  • 表征谱图
  • 同类化合物
  • 相关功能分类
  • 相关结构分类

物化性质

  • 密度:
    1.28
  • 溶解度:
    DMF:20mg/mL; DMSO:10mg/mL;乙醇:10mg/mL; PBS(pH 7.2):2 mg/mL
  • 稳定性/保质期:

    如果按照规格正确使用和储存,则不会分解,也未有已知的危险反应。

计算性质

  • 辛醇/水分配系数(LogP):
    1.4
  • 重原子数:
    35
  • 可旋转键数:
    16
  • 环数:
    2.0
  • sp3杂化的碳原子比例:
    1.0
  • 拓扑面积:
    179
  • 氢给体数:
    7
  • 氢受体数:
    11

安全信息

  • WGK Germany:
    3
  • 海关编码:
    29389090
  • 储存条件:
    密封,在-20°C下保存

SDS

SDS:0467b50054e3704ed9d8107a9c4a1897
查看

上下游信息

  • 上游原料
    中文名称 英文名称 CAS号 化学式 分子量

反应信息

点击查看最新优质反应信息

文献信息

  • Simple preparations of alkyl and cycloalkyl α-glycosides of maltose, cellobiose, and lactose
    作者:Shinkiti Koto、Motoko Hirooka、Takako Tashiro、Motokazu Sakashita、Masaharu Hatachi、Takayuki Kono、Miho Shimizu、Nahoko Yoshida、Sayaka Kurasawa、Natsuko Sakuma、Sunao Sawazaki、Akihiro Takeuchi、Naomi Shoya、Emi Nakamura
    DOI:10.1016/j.carres.2004.07.016
    日期:2004.10
    allyl, 4-pentenyl, and benzyl α-glycosides of maltose, cellobiose, and lactose were prepared (17–77% yield; α/β = 70/30–96/4) via a direct reaction of the free disaccharides with a binary AcBr–AcOH mixture, followed by glycosidation with alcohol using FeCl3 in MeNO2 or CH2Cl2, Zemplen deacetylation, and resolution of the anomeric mixture of glycosides by chromatography. Using MeCN as solvent for the
    摘要麦芽糖纤维二糖乳糖的烷基,环烷基,烯丙基,4-戊烯基和苄基α-糖苷的制备是(17-77%的收率;α/β= 70 / 30-96 / 4)。游离的二糖与二元AcBr-AcOH混合物混合,然后使用FeNO3在MeNO2或CH2Cl2中与酒精进行糖基化,Zemplen脱乙酰化,并通过色谱分离糖苷的异头混合物。使用MeCN作为糖苷化步骤的溶剂,还制备了相应的β-生物苷(16-61%产率;α/β= 25 / 75-5 / 95)。
  • Abdel Salam; El Sawady, Egyptian Journal of Chemistry, 2004, vol. 47, # 2, p. 127 - 142
    作者:Abdel Salam、El Sawady
    DOI:——
    日期:——
  • A Simple Procedure for the Regioselective Synthesis of Fatty Acid Esters of Maltose, Leucrose, Maltotriose and n-Dodecyl Maltosides
    作者:Manuel Ferrer、M Angeles Cruces、Francisco J Plou、Manuel Bernabé、Antonio Ballesteros
    DOI:10.1016/s0040-4020(00)00319-7
    日期:2000.6
    The enzymatic acylation of several di- and trisaccharides with acyl donors ranging from 8 to 18 carbon atoms was carried out by transesterification with the corresponding vinyl esters. The reaction was performed in 2-methyl-2-butanol/dimethylsulfoxide mixtures using the lipase from Humicola lanuginosa (immobilized on Celite). Maltose, maltotriose and n-dodecyl maltosides were specifically acylated in the primary hydroxyl of the non-reducing-end glucose moiety; the acylation of leucrose occurred preferentially in the primary hydroxyl of the glucose ring. (C) 2000 Elsevier Science Ltd. All rights reserved.
  • PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS
    申请人:GRI Bio, Inc.
    公开号:EP3229811B1
    公开(公告)日:2021-02-24
  • [EN] PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS<br/>[FR] PRÉVENTION ET TRAITEMENT DE PATHOLOGIES INFLAMMATOIRES
    申请人:GLYCOREGIMMUNE INC
    公开号:WO2016094226A1
    公开(公告)日:2016-06-16
    In accordance with some embodiments herein, methods and compositions for prevention and treatment of inflammatory conditions are provided. In some embodiments, compositions comprising NKT-2 activators, for example miltefosine are provided. In some embodiments, the compositions further comprise sulfatide and/or a RAR agonist. In some embodiments, the compositions comprise activators of Type II NKT cells, and/or inhibitors of Type I NKT cells.
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