An Efficient Synthesis of Mono-Substituted Benzyl Ferrocene Derivatives
作者:Razack Abdullah、Keunwoo Chung、Young-Wun Kim、In Seok Hong
DOI:10.1002/bkcs.10005
日期:2015.1
The direct alkylation of ferrocene (FC) can be achieved via a Friedel–Craft reaction using an alkyl halide and AlCl3 ; however, this invariably leads to mixtures of mono‐ and poly‐alkylated complexes. Here, we describe the synthesis of mono‐substituted benzyl FC derivatives by a Friedel–Craft reaction utilizing environmentally benign substrates such as benzyl and allyl alcohol and a catalytic amount
Metal-Free Direct Deoxygenative Borylation of Aldehydes and Ketones
作者:Jianbin Li、Haining Wang、Zihang Qiu、Chia-Yu Huang、Chao-Jun Li
DOI:10.1021/jacs.0c03813
日期:2020.7.29
Direct conversion of aldehydes and ketones into alkylboronic esters via deoxygenative borylation represents an unknown yet highly desirable transformation. Herein, we present a one-step and metal-free method for carbonyl deoxy-borylation under mild conditions. A wide range of aromatic aldehydes and ketones are tolerated and successfully converted into the corresponding benzylboronates. By the same
Simple reduction of ferrocenyl aldehydes and ketones by sodium boranuide in trifluoroacetic acid: new, efficient, general preparation of alkylferrocenes
作者:Sukanta Bhattacharyya
DOI:10.1039/p19960001381
日期:——
Alkylferrocenes are obtained in excellent yields by ionic hydrogenation of ferrocenyl aldehydes and ketones using sodium boranuide and trifluoroacetic acid.
(Planar‐Chiral) Ferrocenylmethanols: From Anionic Homo Phospho‐Fries Rearrangements to α‐Ferrocenyl Carbenium Ions
作者:Marcus Korb、Julia Mahrholdt、Heinrich Lang
DOI:10.1002/ejic.201700645
日期:2017.9.15
chlorophosphates gave ferrocenyl phosphates FcCH2OP(O)(OR)2 (Fc = Fe(η5-C5H5)(η4-C5H4)), which readily separate into phosphate anions and ferrocenyl carbo-cations. The latter species undergoes consecutive reactions, e. g. electrophilic aromatic substitutions. When nitriles, instead of alcohols, are treated with FcLi or tBuLi and chlorophosphates, chiral-pool based ferrocenyl imino phosphoramidates
Ionic Hydrogenation of Acylferrocenes Using Zinc Borohydride: An Efficient, Mild Method for the Preparation of Alkylferrocenes
作者:Sukanta Bhattacharyya
DOI:10.1021/om950751n
日期:1996.2.6
An effective mild procedure for the reductive deoxygenation of α-ferrocenyl aldehydes, ketones, and alcohols into the corresponding alkylferrocenes is described using a combination of zinc borohydride and zinc chloride. This is the first example of such reactivity of zinc borohydride. The present method allows the synthesis of alkylferrocenes bearing terminally functionalized pendant chains.