3',5'-二-O-甲磺酰基胸苷 | 56822-33-4

分子结构分类

有机化合物 - 核苷、核苷酸和类似物 - 嘧啶核苷

中文名称

3',5'-二-O-甲磺酰基胸苷

中文别名

——

英文名称

3',5'-di-O-mesylthymidine

英文别名

1-(2-Deoxy-3,5-bis(methylsulfonyl)-β-D-erythro-pentofuranosyl)thymine；3′-O-mesyl-5′-O-mesylthymidine；3',5'-di-O-(methanesulfonyl)-thymidine；3',5'-bis-O-(methylsulfonyl)thymidine；3',5'-di-O-(methanesulfonyl)thymidine；3',5'-Di-O-(methylsulfonyl)thymidine；[(2R,3S,5R)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)-3-methylsulfonyloxyoxolan-2-yl]methyl methanesulfonate

CAS

56822-33-4

化学式

C₁₂H₁₈N₂O₉S₂

mdl

——

分子量

398.415

InChiKey

JPBRYDQRCOMYRY-IVZWLZJFSA-N

BEILSTEIN

——

EINECS

——

物化性质

溶解度：

溶于二甲基亚砜

计算性质

辛醇/水分配系数(LogP)：

-1.1
重原子数：

25
可旋转键数：

6
环数：

2.0
sp3杂化的碳原子比例：

0.67
拓扑面积：

162
氢给体数：

1
氢受体数：

9

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
beta-胸苷	thymidine	146183-25-7	C₁₀H₁₄N₂O₅	242.232
——	Thymidin	157049-40-6	C₁₀H₁₄N₂O₅	242.232
5-甲磺化-2,3`-脱水胸苷	1-(2,3'-Anhydro-5'-O-methylsulfonyl-2-deoxy-β-D-threo-pentofuranosyl)thymine	15981-86-9	C₁₁H₁₄N₂O₆S	302.308

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	3'-O-mesylthymidine	34308-10-6	C₁₁H₁₆N₂O₇S	320.323
——	5'-Desoxy-5'-iod-3'-O-mesyl-thymidin	64032-43-5	C₁₁H₁₅IN₂O₆S	430.22
——	3',4'-anhydrothymidine	7481-90-5	C₁₀H₁₂N₂O₄	224.216
1-(3,5-脱水-2-脱氧-Β-D-苏-戊呋喃糖基)胸腺嘧啶	3'5'-Anhydro thymidine	38313-48-3	C₁₀H₁₂N₂O₄	224.21
3’,5’-脱水胸苷	1-(2-deoxy-3,5-epoxy-β-D-threo-pentofuranosyl)thymine	38313-48-3	C₁₀H₁₂N₂O₄	224.216
2',3'-二脱氧胸苷	3'-Deoxythymidine	3416-05-5	C₁₀H₁₄N₂O₄	226.232
3’-脱氧-3-氟胸苷	alovudine	25526-93-6	C₁₀H₁₃FN₂O₄	244.223
3',5'-二脱氧胸苷	di-deoxythymidine	29108-89-2	C₁₀H₁₄N₂O₃	210.233
——	5-methyl-1-[(2R,5S)-5-(methylsulfanylmethyl)oxolan-2-yl]pyrimidine-2,4-dione	197582-50-6	C₁₁H₁₆N₂O₃S	256.326
——	1-[(2R,5S)-5-(ethylsulfanylmethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione	197582-51-7	C₁₂H₁₈N₂O₃S	270.353
——	3',5'-Diamino-3',5'-dideoxythymidine	64638-15-9	C₁₀H₁₆N₄O₃	240.262
——	3',5'-diazido-2',3',5'-trideoxythymidine	64638-14-8	C₁₀H₁₂N₈O₃	292.257
——	5'-O-mesyl-2,3'-anhydro-thymidine	15981-86-9	C₁₁H₁₄N₂O₆S	302.308
5-甲磺化-2,3`-脱水胸苷	1-(2,3'-Anhydro-5'-O-methylsulfonyl-2-deoxy-β-D-threo-pentofuranosyl)thymine	15981-86-9	C₁₁H₁₄N₂O₆S	302.308
——	1-[(2R,4S,5R)-4-(4-Methoxy-benzylsulfanyl)-5-(4-methoxy-benzylsulfanylmethyl)-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione	183428-15-1	C₂₆H₃₀N₂O₅S₂	514.667
——	5'-[[N-[4-(2',3'-dideoxy-2',3'-didehydrothymidin-5'-yl)butyl]carbamoyl]oxy]-3'-azido-3'-deoxythymidine	——	C₂₆H₃₃N₉O₁₀	631.602
——	1-(3,5-anhydro-2-deoxy-β-D-threo-pentofuranosyl)-2-thiothymine	155807-23-1	C₁₀H₁₂N₂O₃S	240.283
——	1-(3,5-anhydro-2-deoxy-β-D-threo-pentofuranosyl)-2-O-ethylthymine	155807-21-9	C₁₂H₁₆N₂O₄	252.27
司他夫定	stavudin	3056-17-5	C₁₀H₁₂N₂O₄	224.216
——	5'-[[N-[4-(2',3'-dideoxy-2',3'-didehydrothymidin-5'-yl)butyl]carbamoyl]oxy]-2',3'-dideoxy-2',3'-didehydrothymidine	——	C₂₆H₃₂N₆O₁₀	588.574
——	Thymidine, 2',3'-didehydro-3'-deoxy-, 5'-octanoate	134767-53-6	C₁₈H₂₆N₂O₅	350.415
——	5'-hemiglutaryl-2',3'-didehydro-3'-deoxythymidine	152336-79-3	C₁₅H₁₈N₂O₇	338.317
——	2',3'-didehydro-3'-deoxythymidine 5'-O-hemisuccinate	152336-78-2	C₁₄H₁₆N₂O₇	324.29
——	2,3'-anhydro-5'-deoxy-5'-N-morpholinothymidine	——	C₁₄H₁₉N₃O₄	293.323
——	5'-chloro-2',3'-didehydro-3',5'-dideoxythymidine	33799-54-1	C₁₀H₁₁ClN₂O₃	242.662
——	5'-O-[(vinyloxy)carbonyl]-2',3'-dideoxy-2',3'-didehydrothymidine	775323-14-3	C₁₃H₁₄N₂O₆	294.264
——	3'-deoxy-2,3'-didehydro-5'-ethylthio thymidine	197582-45-9	C₁₂H₁₆N₂O₃S	268.337
——	[(2S,5R)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)-2,5-dihydrofuran-2-yl]methyl (4-nitrophenyl) carbonate	928138-25-4	C₁₇H₁₅N₃O₈	389.321
——	5-methyl-1-[(2R,5S)-5-(methylsulfanylmethyl)-2,5-dihydrofuran-2-yl]pyrimidine-2,4-dione	197582-44-8	C₁₁H₁₄N₂O₃S	254.31
——	5'-monomethoxytritylamino-3'-(N'-9-fluorenylmethoxycarbonylthiouria)-2',3',5'-trideoxythymidine	556826-39-2	C₄₆H₄₃N₅O₆S	793.943
——	1-[(2R,5S)-5-(ethylsulfonylmethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-dione	197582-49-3