Deacylgymnemic acid | 121686-42-8

• 物质功能分类: 分析化学 - 标准品 - 分析标准品
• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: Deacylgymnemic acid
• 英文别名: (2S,3S,4S,5R,6R)-6-[[(6aR,6bS,8R,8aR,9S,10S,12aR,14bR)-8,9,10-trihydroxy-4,8a-bis(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid
• CAS: 121686-42-8
• 化学式: C₃₆H₅₈O₁₂
• 分子量: 682.8
• InChiKey: NXUZSZLFZAMZLC-BNLARJOSSA-N

物化性质

• 密度：
  1.39

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  48
• 可旋转键数：
  5
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  218
• 氢给体数：
  9
• 氢受体数：
  12

安全信息

• WGK Germany：
  3

文献信息

• Sweet Taste Receptor Antagonist Compositions
  申请人：Four LLC

  公开号：US20150359809A1

  公开（公告）日：2015-12-17

  The present disclosure relates to compositions comprising gymnemic acid, together with a form of zinc to block the unpleasant bitter taste of gymnemic acid as well as to extend the sweet taste blocking properties of gymnemic acid, resulting in palatable compositions for delivery to the oral cavity to block sweet taste receptors located therein. The present disclosure also relates to methods of reducing sugar consumption and reducing calorie intake via administration of such compositions to a subject.
• SWEET TASTE RECEPTOR ANTAGONIST COMPOSITIONS
  申请人：Four LLC

  公开号：US20160303149A1

  公开（公告）日：2016-10-20

  The present disclosure relates to compositions comprising gymnemic acid, together with a form of zinc to block the unpleasant bitter taste of gymnemic acid as well as to extend the sweet taste blocking properties of gymnemic acid, resulting in palatable compositions for delivery to the oral cavity to block sweet taste receptors located therein. The present disclosure also relates to methods of reducing sugar consumption and reducing calorie intake via administration of such compositions to a subject.
• US9421217B2
  申请人：——

  公开号：US9421217B2

  公开（公告）日：2016-08-23
• US9585905B2
  申请人：——

  公开号：US9585905B2

  公开（公告）日：2017-03-07