5-hydroxy-1-[(1R,2S,5R)-(-)-menthoxymethyl]-2-methyl-pyridinium chloride

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 5-hydroxy-1-[(1R,2S,5R)-(-)-menthoxymethyl]-2-methyl-pyridinium chloride
• 英文别名: 6-methyl-1-[[(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl]oxymethyl]pyridin-1-ium-3-ol;chloride
• 化学式: C₁₇H₂₈NO₂*Cl
• 分子量: 313.868
• InChiKey: ABNIEGMQLXPUNF-GDDRIFLCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.43
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  33.3
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  3-羟基-6-甲基吡啶 、 (-)-氯甲基薄荷醚 以 N,N-二甲基甲酰胺 为溶剂， 以98%的产率得到5-hydroxy-1-[(1R,2S,5R)-(-)-menthoxymethyl]-2-methyl-pyridinium chloride
  参考文献：
  名称：

  Chiral pyridinium-based ionic liquids containing the (1R,2S,5R)-(−)-menthyl group

  摘要：

  A novel class of chiral pyridinium salts in which the chirality resides in the cation have been prepared and characterized. The physicochemical and anti-microbial properties have been determined. The group of prepared salts contained chiral ionic liquids and decomposable chiral pyridinium chlorides. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2006.06.014

文献信息

• Chiral pyridinium-based ionic liquids containing the (1R,2S,5R)-(−)-menthyl group
  作者：Juliusz Pernak、Joanna Feder-Kubis

  DOI：10.1016/j.tetasy.2006.06.014

  日期：2006.7

  A novel class of chiral pyridinium salts in which the chirality resides in the cation have been prepared and characterized. The physicochemical and anti-microbial properties have been determined. The group of prepared salts contained chiral ionic liquids and decomposable chiral pyridinium chlorides. (c) 2006 Elsevier Ltd. All rights reserved.