乙二醇双(4-羧苯基) 醚 | 3753-05-7

• 物质功能分类: 有机原料 - 醚类化合物及其衍生物
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 乙二醇双(4-羧苯基) 醚
• 中文别名: 乙二醇双(4-羧苯基)醚；乙二醇双(对羧基苯)醚
• 英文名称: 1,2-bis(phenoxy)ethane-4,4'-dicarboxylic acid
• 英文别名: 1,2-bis(4-carboxyphenoxy)ethane；Benzoic acid, 4,4'-[1,2-ethanediylbis(oxy)]bis-；4-[2-(4-carboxyphenoxy)ethoxy]benzoic acid
• CAS: 3753-05-7
• 化学式: C₁₆H₁₄O₆
• 分子量: 302.284
• InChiKey: VAXBLYWAVAIJJJ-UHFFFAOYSA-N

物化性质

• 熔点：
  352-355 °C
• 沸点：
  546.2±35.0 °C(Predicted)
• 密度：
  1.353±0.06 g/cm3(Predicted)
• 稳定性/保质期：

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  22
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  93.1
• 氢给体数：
  2
• 氢受体数：
  6

安全信息

• 海关编码：
  2918990090
• 储存条件：
  室温且干燥

SDS

Ethylene Glycol Bis(4-carboxyphenyl) Ether Revision number: 5
SAFETY DATA SHEET

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Section 1. IDENTIFICATION
Product name: Ethylene Glycol Bis(4-carboxyphenyl) Ether

Revision number: 5

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Section 2. HAZARDS IDENTIFICATION
GHS classification
PHYSICAL HAZARDS Not classified
Not classified
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS Not classified
GHS label elements, including precautionary statements
Pictograms or hazard symbols None
No signal word
Signal word
Hazard statements None
None
Precautionary statements:

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Section 3. COMPOSITION/INFORMATION ON INGREDIENTS
Substance/mixture: Substance
Components: Ethylene Glycol Bis(4-carboxyphenyl) Ether
Percent: >95.0%(T)
CAS Number: 3753-05-7
Synonyms: 1,2-Bis(4-carboxyphenoxy)ethane
Chemical Formula: C16H14O6

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Section 4. FIRST AID MEASURES
Inhalation: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
Get medical advice/attention if you feel unwell.
Skin contact: Remove/Take off immediately all contaminated clothing. Rinse skin with
water/shower. If skin irritation or rash occurs: Get medical advice/attention.
Eye contact: Rinse cautiously with water for several minutes. Remove contact lenses, if present
and easy to do. Continue rinsing. If eye irritation persists: Get medical
advice/attention.
Ingestion: Get medical advice/attention if you feel unwell. Rinse mouth.
Protection of first-aiders: A rescuer should wear personal protective equipment, such as rubber gloves and air-
tight goggles.

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Section 5. FIRE-FIGHTING MEASURES
Suitable extinguishing Dry chemical, foam, water spray, carbon dioxide.
media:
Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing
method according to the surrounding situation is used. Uninvolved persons should
evacuate to a safe place. In case of fire in the surroundings: Remove movable
containers if safe to do so.

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Section 5. FIRE-FIGHTING MEASURES
Special protective When extinguishing fire, be sure to wear personal protective equipment.
equipment for firefighters:

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Section 6. ACCIDENTAL RELEASE MEASURES
Personal precautions, Use personal protective equipment. Keep people away from and upwind of spill/leak.
protective equipment and Entry to non-involved personnel should be controlled around the leakage area by
emergency procedures: roping off, etc.
Environmental precautions: Prevent product from entering drains.
Methods and materials for Sweep dust to collect it into an airtight container, taking care not to disperse it.
containment and cleaning Adhered or collected material should be promptly disposed of, in accordance with
up: appropriate laws and regulations.

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Section 7. HANDLING AND STORAGE
Precautions for safe handling
Handling is performed in a well ventilated place. Wear suitable protective equipment.
Technical measures:
Prevent dispersion of dust. Wash hands and face thoroughly after handling.
Use a local exhaust if dust or aerosol will be generated.
Advice on safe handling: Avoid contact with skin, eyes and clothing.
Conditions for safe storage, including any
incompatibilities
Keep container tightly closed. Store in a cool and dark place.
Storage conditions:
Store away from incompatible materials such as oxidizing agents.
Packaging material: Comply with laws.

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Section 8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Engineering controls: Install a closed system or local exhaust as possible so that workers should not be
exposed directly. Also install safety shower and eye bath.
Personal protective equipment
Respiratory protection: Dust respirator. Follow local and national regulations.
Hand protection: Protective gloves.
Eye protection: Safety glasses. A face-shield, if the situation requires.
Skin and body protection: Protective clothing. Protective boots, if the situation requires.

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Section 9. PHYSICAL AND CHEMICAL PROPERTIES
Physical state (20°C): Solid
Form: Crystal- Powder
Colour: White - Almost white
Odour: No data available
pH: No data available
Melting point/freezing point:No data available
Boiling point/range: No data available
Flash point: No data available
Flammability or explosive
limits:
No data available
Lower:
Upper: No data available
No data available
Relative density:
Solubility(ies):
[Water] No data available
[Other solvents] No data available

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Section 10. STABILITY AND REACTIVITY
Stable under proper conditions.
Chemical stability:
Possibility of hazardous No special reactivity has been reported.
reactions:
Incompatible materials: Oxidizing agents

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Section 10. STABILITY AND REACTIVITY
Hazardous decomposition Carbon monoxide, Carbon dioxide
products:

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Section 11. TOXICOLOGICAL INFORMATION
Acute Toxicity: No data available
Skin corrosion/irritation: No data available
Serious eye No data available
damage/irritation:
Germ cell mutagenicity: No data available
Carcinogenicity:
IARC = No data available
NTP = No data available
Reproductive toxicity: No data available

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Section 12. ECOLOGICAL INFORMATION
Ecotoxicity:
No data available
Fish:
Crustacea: No data available
No data available
Algae:
Persistence / degradability: No data available
No data available
Bioaccumulative
potential(BCF):
Mobility in soil
Log Pow: No data available
No data available
Soil adsorption (Koc):
Henry's Law No data available
constant(PaM3/mol):

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Section 13. DISPOSAL CONSIDERATIONS
Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material
with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system.
Observe all federal, state and local regulations when disposing of the substance.

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Section 14. TRANSPORT INFORMATION
Hazards Class: Does not correspond to the classification standard of the United Nations
Not listed
UN-No:

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Section 15. REGULATORY INFORMATION
Safe management ordinance of dangerous chemical product (State Council announces on January 26, 2002
and revised on February 16,2011): Safe use and production, the storage of a dangerous chemical, transport,
loading and unloading were prescribed.

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SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  乙二醇双(4-羧苯基) 醚 在 硫酸 、 sodium chloride 作用下， 以 水 为溶剂， 反应 48.0h， 以69%的产率得到1,2-bis(sodium-2-sulfonate-4-carboxyphenoxy)ethane
  参考文献：
  名称：

  坚固的多功能基于Zr的金属-有机多面体，可实现高质子传导性和选择性CO 2捕获†

  摘要：

  通过自组装设计的柔性磺酸盐-羧酸盐配体，1,2-双（-2-磺酸钠-4-羧基苯氧基）乙烷（NaH）的自组装，已经设计和构建了新的稳定的基于Zr的金属有机多面体（MOP）。2 L），以及次级结构单元（的SBU）Cp的3的Zr 3（μ 3 -O）（μ 2 -OH）3，（CP =η 5 -C 5 H ^ 5）。MOP具有糖果状的笼状结构，并且有机配体上的阴离子磺酸基团通过与阳离子SBU形成强大的多重电荷辅助氢键，增强了MOP的稳定性（热稳定性以及耐酸和碱性）。这种3D多孔框架的独特腔体使MOP具有高度选择性的CO 2捕获能力。通过在离散的MOP之间连接配位的水分子和自由水分子而获得的2D H键网络使质子电导率在30°C，98％相对湿度（RH）和30°C时达到1.41×10 -3 S cm -1。质子转移的活化能低至0.225 eV。

  DOI：

  10.1039/c8ta00858b
• 作为产物：
  描述：

  1-甲基-4-[2-(4-甲基苯氧基)乙氧基]苯 在 cobalt(II) acetate 、 manganese triacetate 二叔丁基过氧化物 、 氧气 、 丁酸 作用下， 生成 乙二醇双(4-羧苯基) 醚
  参考文献：
  名称：

  van Helden,R. et al., Recueil des Travaux Chimiques des Pays-Bas, 1961, vol. 80, p. 1237 - 1253

  摘要：

  DOI：
• 作为试剂：
  描述：

  zinc(II) chloride dihydrate 、 4,4'-bis(2-methylimidazol-1-ylmethyl)biphenyl 在 乙二醇双(4-羧苯基) 醚 、 sodium hydroxide 作用下， 以 甲醇 、 水 为溶剂， 反应 72.0h， 生成 [Zn(bi)(Cl)₂]_n
  参考文献：
  名称：

  两种新型一维配位聚合物：合成，结构和性质

  摘要：

  两种新的配位聚合物，即[Zn（bi）（Cl）2] n（1）和[Cu（L）2（bib）（H 2 O）2] n（2）（bi = 4,4'-合成双（2-甲基咪唑-1-基甲基）联苯; L = 4-（2-（4-（甲氧基羰基）苯氧基）乙氧基）苯甲酸和bib = 2,3-双（4-吡啶基）丁烷）并合成表征。1和2都具有一维共价链，这些共价链显示出不同的共形链特征。在1和2中分别观察到2D超分子菱形和矩形图案。O–H··O和C–H···Cl氢键相互作用在促进结构模式的多样性方面起着重要作用。关键词：结构，超分子相互作用，发光牛。化学 Soc。埃塞俄比亚。2014，28（3），415-422。DOI：http：//dx.doi.org/10.4314/bcse.v28i3.11

  DOI：

  10.4314/bcse.v28i3.11

文献信息

• FGF-RECEPTOR AGONIST DIMERIC COMPOUNDS
  申请人：BONO Francoise

  公开号：US20090069368A1

  公开（公告）日：2009-03-12

  FGF receptor agonist compounds corresponding to the general formula: M1-L-M2 are disclosed in which M1 and M2, which may be identical or different, each represent, independently of one another, a monomer unit M, and L represents a linker group, wherein the monomer unit is of the general formula I.

  公开了对应于一般公式 M1-L-M2 的FGF受体激动剂化合物，其中M1和M2相同或不同，每个独立地表示一个单体单元M，L表示连接基团，其中单体单元是通用公式I。
• OXYGEN-ABSORBING RESIN COMPOSITION, AND MULTILAYER BODY, CONTAINER, INJECTION-MOLDED BODY, AND MEDICAL CONTAINER USING SAME
  申请人：MITSUBISHI GAS CHEMICAL COMPANY, INC.

  公开号：US20150298887A1

  公开（公告）日：2015-10-22

  Provided are a novel oxygen-absorbing resin composition not responsive to a metal detector, producing no odor after absorption of oxygen and having excellent oxygen-absorbing performance, and a multilayer body, container, injection-molded article and medical container using these. Further provided are an oxygen-absorbing resin composition etc. having excellent oxygen-absorbing performance in a wide range of humidity conditions from low humidity to high humidity. The oxygen-absorbing resin composition of the present invention is an oxygen-absorbing resin composition containing a polyamide compound and a transition metal catalyst, wherein the polyamide compound has at least one constituent unit having a tetralin ring. Moreover, the multilayer body, container, injection-molded article, medical container, etc. of the present invention are obtained by using the oxygen-absorbing resin composition of the present invention.

  提供了一种新型的氧吸收树脂组合物，对金属探测器不敏感，在吸收氧气后不产生气味，具有出色的吸氧性能，以及使用这些的多层体、容器、注塑制品和医用容器。此外，还提供了一种氧吸收树脂组合物等，在从低湿度到高湿度的广泛湿度条件下具有出色的吸氧性能。本发明的氧吸收树脂组合物是一种含有聚酰胺化合物和过渡金属催化剂的氧吸收树脂组合物，其中聚酰胺化合物至少具有一个具有四氢萘环的组分单元。此外，本发明的多层体、容器、注塑制品、医用容器等是通过使用本发明的氧吸收树脂组合物获得的。
• Interpenetrating metal-organic frameworks formed by self-assembly of tetrahedral and octahedral building blocks
  作者：Yong-Ming Lu、Ya-Qian Lan、Yan-Hong Xu、Zhong-Min Su、Shun-Li Li、Hong-Ying Zang、Guang-Juan Xu

  DOI：10.1016/j.jssc.2009.08.018

  日期：2009.11

  elemental analyses, IR spectra, and thermogravimetric (TG) analyses. Compounds 1–3 display α-Po topological nets with different degrees of interpenetration based on the similar octahedral [Cd2(–COO)4] building blocks. Compound 4 is a six-fold interpenetrating diamondoid net based on tetrahedral MBBs. By careful inspection of these structures, we find that various carboxylic ligands and N-donor ligands with

  为了研究拓扑类型与分子构造块（MBB）之间的关系，我们设计并合成了一系列在水热条件下基于不同多边形或多面体的三维（3D）互穿金属有机骨架，即[Cd（bpib）0.5（L 1）]（1），[Cd（bpib）0.5（L 2）]·H 2 O（2），[Cd（bpib）0.5（L 3）]（3）和[Cd（bib）0.5（L 1）]（4），其中bpib = 1,4-双（2-（吡啶-2-基）-1 H-咪唑-1-基）丁烷，bib = 1,4-双（1 H-咪唑-1-基）丁烷，H 2 L 1 = 4-（4-羧基苄氧基）苯甲酸，H 2 L 2 = 4,4'-（乙烷-1,2-二基双（氧基））二苯甲酸和H 2 L 3分别为4,4'-（1,4-亚苯基双（亚甲基））双（氧基）二苯甲酸。它们的结构已通过单晶X射线衍射分析确定，并进一步通过元素分析，IR光谱和热重（TG）分析进行了表征。化合物1 - 3显示α-宝拓扑网以基于所
• Process for preparing
  申请人：Toray Industries, Inc.

  公开号：US04531009A1

  公开（公告）日：1985-07-23

  A process for producing an .alpha.,.omega.-bis(2-chlorophenoxy)alkane-4,4'-dicarboxylic acid or its ester, that has a high Young's modulus and that is useful as a material for polyesters capable to form self-extinguishing fibers and films. Thus .alpha.,.omega.-bis(2-chlorophenoxy)alkane-4,4'-dicarboxylic acid or its ester is obtained by reacting .alpha.,.omega.-bis(phenoxy)alkane-4,4'-dicarboxylic acid or its ester with chlorine in the presence of a solvent selected from the group consisting of lower fatty acid having 2 to 6 carbon atoms, hydrocarbon chloride having 1 to 8 carbon atoms, and carbon chloride having 1 to 2 carbon atoms, in high yield.

  一种生产高Young模量的α，ω-双（2-氯苯氧基）烷基-4,4'-苯二甲酸或其酯的方法，其可用作能够形成自灭火纤维和薄膜的聚酯材料。因此，在低级脂肪酸（具有2至6个碳原子），具有1至8个碳原子的烃基氯化物和具有1至2个碳原子的碳氯化物的溶剂存在下，通过将α，ω-双（苯氧基）烷基-4,4'-苯二甲酸或其酯与氯反应，高收率地得到α，ω-双（2-氯苯氧基）烷基-4,4'-苯二甲酸或其酯。
• Encapsulation and Sensitization of UV–vis and Near Infrared Lanthanide Hydrate Emitters for Dual- and Bimodal-Emissions in Both Air and Aqueous Media Based on a Porous Heteroatom-Rich Cd(II)-Framework
  作者：Yan-An Li、Shu-Kui Ren、Qi-Kui Liu、Jian-Ping Ma、Xueyuan Chen、Haomiao Zhu、Yu-Bin Dong

  DOI：10.1021/ic300665a

  日期：2012.9.17

  A porous heteroatom-rich Cd(II)-polymeric framework which is generated from an ethylene glycol ether-bridging dicarboxylate ligand L, 4,4′-bipy and Cd(II) ion is reported. It contains one-dimensional tubes (9–11 Å) which are able to trap cationic lanthanide hydrates such as Eu(H2O)83+, Tb(H2O)83+, and Nd(H2O)83+ under ambient conditions to generate Ln(H2O)83+-loaded materials. In addition, the heteroatom-rich

  报道了由乙二醇醚桥联的二羧酸酯配体L，4，4′-联吡啶和Cd（II）离子产生的多孔的富含杂原子的Cd（II）-聚合物骨架。它包含一维管（9-11Å），能够捕获阳离子镧系元素水合物，例如Eu（H 2 O）8 3+，Tb（H 2 O）8 3+和Nd（H 2 O）8 3+在环境条件下生成负载Ln（H 2 O）8 3+的材料。此外，富含杂原子的主体材料可以有效保护和敏化封装的Ln 3+在空气和水介质中呈水合物形式的发射体。此外，基于客体驱动方法，通过插入不同的Ln 3+-水合物成功实现了双峰和双峰排放。