3-O-β-D-glucopyranosyl-(1→4)-β-D-glucopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl-23-hydroxyolean lup-20(29)-en-28-oic acid O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 3-O-β-D-glucopyranosyl-(1→4)-β-D-glucopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl-23-hydroxyolean lup-20(29)-en-28-oic acid O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester
• 化学式: C₆₅H₁₀₆O₃₂
• 分子量: 1399.54
• InChiKey: MHOBLQYKNDTPHI-RZFFPRCOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -5.89
• 重原子数：
  97.0
• 可旋转键数：
  18.0
• 环数：
  11.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  512.2
• 氢给体数：
  19.0
• 氢受体数：
  32.0

反应信息

• 作为反应物：
  描述：

  3-O-β-D-glucopyranosyl-(1→4)-β-D-glucopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl-23-hydroxyolean lup-20(29)-en-28-oic acid O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester 在 硫酸 作用下， 以 1,4-二氧六环 为溶剂， 反应 1.0h， 生成 L-阿拉伯糖 、 L-鼠李糖 、 葡萄糖
  参考文献：
  名称：

  Isolation and characterization of new minor triterpenoid saponins from the buds of Lonicera macranthoides

  摘要：

  Three new minor compounds, 18-oleanene (1), lupine (2), and 12-oleanene (3) type triterpenoid saponins, along with four major known triterpenoid saponins were isolated from the buds of Lonicera macranthoides. Their structures were elucidated by spectroscopic and chemical analyses. 18-oleanene and lupine-type triterpenoid saponins were first isolated from this plant. The isolated compounds were evaluated for their cytotoxic activities against HSC-2 cells. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2013.01.019

文献信息

• Isolation and characterization of new minor triterpenoid saponins from the buds of Lonicera macranthoides
  作者：Jiang Liu、Jing Zhang、Feng Wang、Yuan-feng Zou、Xing-fu Chen

  DOI：10.1016/j.carres.2013.01.019

  日期：2013.4

  Three new minor compounds, 18-oleanene (1), lupine (2), and 12-oleanene (3) type triterpenoid saponins, along with four major known triterpenoid saponins were isolated from the buds of Lonicera macranthoides. Their structures were elucidated by spectroscopic and chemical analyses. 18-oleanene and lupine-type triterpenoid saponins were first isolated from this plant. The isolated compounds were evaluated for their cytotoxic activities against HSC-2 cells. (C) 2013 Elsevier Ltd. All rights reserved.