亚油酸钠 | 822-17-3

• 物质功能分类: 有机原料 - 有机金属类化合物 - 有机钠
• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 亚油酸钠
• 中文别名: 顺,顺-9,12-十八碳二烯酸钠盐
• CAS: 822-17-3
• 化学式: C18H32NaO2
• 分子量: 303.4
• InChiKey: XDGBPYHYBRCREM-NBTZWHCOSA-N

物化性质

• 熔点：
  192 °C
• 溶解度：
  溶于乙醇

计算性质

• 辛醇/水分配系数(LogP)：
  5.5
• 重原子数：
  21
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.72
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 危险品标志：
  Xi
• 安全说明：
  S36
• 危险类别码：
  R38
• WGK Germany：
  3
• 危险性防范说明：
  P280
• 危险性描述：
  H315

制备方法与用途

亚油酸是一种n-6多不饱和必需脂肪酸（PUFA），可用作花生四烯酸（AA）和多种前列腺素的前体。此外，亚油酸还能用于提高抗癌药物的传递效率及其疗效。

文献信息

• BORON-CONTAINING SMALL MOLECULES
  申请人：Xia Yi

  公开号：US20100256092A1

  公开（公告）日：2010-10-07

  This invention relates to, among other items, 6-substituted benzoxaborole compounds and their use for treating bacterial infections.

  这项发明涉及6-取代苯硼酯化合物等物品，以及它们用于治疗细菌感染的用途。
• [EN] BORON-CONTAINING SMALL MOLECULES<br/>[FR] PETITES MOLECULES CONTENANT DU BORE
  申请人：ANACOR PHARMACEUTICALS INC

  公开号：WO2011094450A1

  公开（公告）日：2011-08-04

  Compounds, pharmaceutical formulations, and methods of treating anti-inflammatory conditions and/or helminth-associated diseases are disclosed.

  公开了化合物、药物配方以及治疗抗炎条件和/或蠕虫相关疾病的方法。
• Boron-Containing Small Molecules as Anti-Inflammatory Agents
  申请人：ANACOR PHARMACEUTICALS, INC.

  公开号：US20150291629A1

  公开（公告）日：2015-10-15

  Compounds and methods of treating anti-inflammatory conditions are disclosed.

  化合物和治疗抗炎症状况的方法被披露。
• BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF
  申请人：SENOMYX, INC.

  公开号：US20160376263A1

  公开（公告）日：2016-12-29

  The present invention includes compounds and compositions known to modify the perception of bitter taste, and combinations of said compositions and compounds with additional compositions, compounds, and products. Exemplary compositions comprise one or more of the following: cooling agents; inactive drug ingredients; active pharmaceutical ingredients; food additives or foodstuffs; flavorants, or flavor enhancers; food or beverage products; bitter compounds; sweeteners; bitterants; sour flavorants; salty flavorants; umami flavorants; plant or animal products; compounds known to be used in pet care products; compounds known to be used in personal care products; compounds known to be used in home products; pharmaceutical preparations; topical preparations; cannabis-derived or cannabis-related products; compounds known to be used in oral care products; beverages; scents, perfumes, or odorants; compounds known to be used in consumer products; silicone compounds; abrasives; surfactants; warming agents; smoking articles; fats, oils, or emulsions; and/or probiotic bacteria or supplements.

  本发明涵盖已知用于改变苦味感知的化合物和组合物，以及所述组合物和化合物与额外的组合物、化合物和产品的组合。示例组合物包括以下一种或多种：冷却剂；无活性药物成分；活性药用成分；食品添加剂或食品；调味剂或调味增强剂；食品或饮料产品；苦味化合物；甜味剂；苦味剂；酸味调味剂；咸味调味剂；鲜味调味剂；植物或动物产品；已知用于宠物护理产品中的化合物；已知用于个人护理产品中的化合物；已知用于家用产品中的化合物；制药制剂；局部制剂；大麻衍生或与大麻相关的产品；已知用于口腔护理产品中的化合物；饮料；香味、香水或除臭剂；已知用于消费品中的化合物；硅化合物；磨料；表面活性剂；发热剂；吸烟物品；脂肪、油脂或乳化剂；和/或益生菌或补充剂。
• [EN] SURFACTANTS FOR HEALTHCARE PRODUCTS<br/>[FR] TENSIOACTIFS POUR PRODUITS DE SOINS DE SANTÉ
  申请人：ADVANSIX RESINS & CHEMICALS LLC

  公开号：WO2021183582A1

  公开（公告）日：2021-09-16

  Healthcare formulations, including, inventive surfactants, Active ingredient formulated as solids, liquids, or emulsions. The present disclosure provides formulations of healthcare products, such as: prescription drugs, over the counter drugs; minerals, herbal, and/or vitamin supplements; drugs administered in hospitals, clinics, physician's office, and places of palliative care; vaccines, tissue, organ, and cell transplants and/or grafts and/or infusions; and wound care formulations including topical ointments, lotions, cleaners, wipes, bandages, and dressings. The Active may be included in the formulations as a solute, a solvent, a particle, or an oil immiscible component of the formulation. The Active may be included in tablets, capsules, tinctures, liquids, or emulsions. Inventive healthcare formulations include formulations suitable for administration orally, topically, and/or by injection.

  医疗保健配方，包括创新表面活性剂，活性成分制剂为固体、液体或乳液。本公开提供医疗保健产品的配方，如：处方药、非处方药；矿物质、草药和/或维生素补充剂；在医院、诊所、医生办公室和临终关怀场所使用的药物；疫苗、组织、器官和细胞移植和/或移植和/或输注；以及包括局部药膏、乳液、清洁剂、湿巾、绷带和敷料的伤口护理配方。活性成分可以作为溶质、溶剂、颗粒或配方中的油不相溶成分包含在配方中。活性成分可以包含在片剂、胶囊、药液或乳剂中。创新的医疗保健配方包括适用于口服、局部和/或注射的配方。