3-(tri-n-butylstannyl)quinoline

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 3-(tri-n-butylstannyl)quinoline
• 英文别名: 3-(tributylstannyl)quinoline
• 化学式: C₂₁H₃₃NSn
• 分子量: 418.21
• InChiKey: GRCFGVMZXVNIFA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.29
• 重原子数：
  23
• 可旋转键数：
  10
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  12.9
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  二苯并[B,F][1,5]二氮杂辛因-6,12(5H,11H)-二酮 、 3-(tri-n-butylstannyl)quinoline 在 四(三苯基膦)钯 作用下， 以 甲苯 为溶剂， 反应 24.0h， 以80%的产率得到
  参考文献：
  名称：

  반방향족성 화합물 및 이를 포함하는 유기 발광 소자

  摘要：

  含有反向共轭结构的化合物和有机发光器件被提出。

  公开号：

  KR20150142709A
• 作为产物：
  描述：

  3-溴喹啉 、 三丁基氯化锡 在 正丁基锂 作用下， 以 四氢呋喃 为溶剂， 反应 13.0h， 以70%的产率得到3-(tri-n-butylstannyl)quinoline
  参考文献：
  名称：

  반방향족성 화합물 및 이를 포함하는 유기 발광 소자

  摘要：

  含有反向共轭结构的化合物和有机发光器件被提出。

  公开号：

  KR20150142709A

文献信息

• Sequential oxopyridinium betaine cycloaddition–palladium catalysed cyclisation–anion capture processes
  作者：Mark R Fielding、Ronald Grigg、Visuvanathar Sridharan、Mark Thornton-Pett、Christopher J Urch

  DOI：10.1016/s0040-4020(01)00740-2

  日期：2001.9

  Katritzky's oxopyridinium. betaine cycloaddition is employed to generate bridged bicyclic substrates suitable for our palladium(0) catalysed cyclisation-anion capture methodology. A variety of polycyclic heterocycles have been synthesised via monocyclisation-organotin(IV) capture with or without incorporation of carbon monoxide. Sequential cycloaddition-cyclisation can be performed as a one pot process to deliver substantial gain in molecular complexity. (C) 2001 Elsevier Science Ltd. All rights reserved.
• Molecular receptors for monosaccharides: di(pyridyl)naphthyridine and di(quinolyl)naphthyridine
  作者：Weibing Lu、Li-He Zhang、Xin-Shan Ye、Jiachun Su、Zhixiang Yu

  DOI：10.1016/j.tet.2005.11.048

  日期：2006.2

  The recognition capabilities of two molecular receptors 2,7-di(3'-pyridyl)-1,8-naphthyridine (DPN) and 2,7-di(3'-quinolyl)-1,8-naphthyridine (DQN) toward monosaccharides in chloroform were evaluated. Both DPN and DQN possess a naphthyridine core moiety, in which two pyridinic nitrogen atoms serve as the proton acceptors. Attached to the C2 and C7 positions of naphthyridine are two identical arms, each of which consists of pyridine (DPN) or quinoline (DQN) moiety that also acts as the proton acceptor. The arrangement of hydroxyl groups in monosaccharides offers the proton donors complementary to the proton acceptors of DPN (or DQN) to form a quadruply hydrogen bonds complex. The binding processes were studied by UV-vis, fluorescence and H-1 NMR spectrophotometric titrations as well as electrospray ionization mass spectroscopy. The binding strength between DPN (or DQN) and examined monosaccharides was comparable to that for man other hydrogen-bonding host molecules previously reported. (c) 2005 Elsevier Ltd. All rights reserved.
• A versatile new synthesis of 4-aryl- and heteroaryl-[3,4-c]pyrrolocarbazoles by [4+2] cycloaddition followed by palladium catalysed cross coupling
  作者：Gary McCort、Olivier Duclos、Caroline Cadilhac、Eric Guilpain

  DOI：10.1016/s0040-4039(99)01142-9

  日期：1999.8

  4-Bromo- and 4-trifluorosulfonyloxypyrrolo[3,4-c]carbazoles were prepared in five steps via a [4+2] cycloaddition and were used as key intermediates in palladium-catalysed cross coupling reactions allowing the rapid generation of structurally diverse protein kinase C inhibitors. (C) 1999 Published by Elsevier Science Ltd. All rights reserved.
• Discovery of 5-(1H-indol-5-yl)-1,3,4-thiadiazol-2-amines as potent PIM inhibitors
  作者：Bin Wu、Hui-Ling Wang、Victor J. Cee、Brian A. Lanman、Thomas Nixey、Liping Pettus、Anthony B. Reed、Ryan P. Wurz、Nadia Guerrero、Christine Sastri、Jeff Winston、J. Russell Lipford、Matthew R. Lee、Christopher Mohr、Kristin L. Andrews、Andrew S. Tasker

  DOI：10.1016/j.bmcl.2014.12.091

  日期：2015.2

  PIM kinases are a family of Ser/Thr kinases that are implicated in tumorigenesis. The discovery of a new class of PIM inhibitors, 5-(1H-indol-5-yl)-1,3,4-thiadiazol-2-amines, is discussed with optimized compounds showing excellent potency against all three PIM isoforms. (C) 2015 Elsevier Ltd. All rights reserved.
• 반방향족성 화합물 및 이를 포함하는 유기 발광 소자
  申请人：Samsung Display Co., Ltd. 삼성디스플레이 주식회사(120120164552) Corp. No ▼ 134511-0187812

  公开号：KR20150142709A

  公开（公告）日：2015-12-23

  반방향족성 화합물 및 이를 포함한 유기 발광 소자가 개시된다.

  含有反向共轭结构的化合物和有机发光器件被提出。