A particulate composition comprises pullulan and concomitant saccharides containing mannitol, and has the following features:
said pullulan and said concomitant saccharides are respectively insoluble and soluble in 75% by volume of methanol in water;
the content of said pullulan against the content of the total saccharides in the whole of said particulate composition is 97% by weight or higher, when determined based on the anthrone sulfuric acid method;
the content of said concomitant saccharides against the content of the total saccharides in the whole of said particulate composition is 3% by weight or lower, when determined based on the anthrone sulfuric acid method;
the content of said mannitol against the content of the total saccharides in the whole of said particulate composition does not exceed 2% by weight, on a dry solid basis; and
the weight-average molecular weight of said pullulan is 50,000 to 1,000,000 Daltons.
一种颗粒组合物由拉鲁兰和含有
甘露醇的伴生糖组成,具有以下特点:
所述拉普兰和伴生糖分别不溶于和溶于体积分数为 75%的
甲醇水;
根据
蒽酮硫酸法测定,在整个颗粒组合物中,所述拉鲁兰的含量占总糖含量的重量比为 97% 或更高;
根据
蒽酮硫酸法测定,所述伴生糖的含量与所述颗粒组合物中总糖的含量之比为 3%(以重量计)或更低;
以干固体为基准,所述
甘露醇的含量相对于整个所述微粒组合物中总糖的含量不超过 2%(以重量计);以及
所述拉鲁兰的重量平均分子量为 50,000 至 1,000,000 道尔顿。