1,6-己二醇二乙烯醚 | 19763-13-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 1,6-己二醇二乙烯醚
• 中文别名: 1,6-己二醇基二乙烯基醚
• 英文名称: 1,6-bis(vinyloxy)hexane
• 英文别名: 1,6-bis(ethenoxy)hexane
• CAS: 19763-13-4
• 化学式: C₁₀H₁₈O₂
• mdl: MFCD00192206
• 分子量: 170.252
• InChiKey: JOSFJABFAXRZJQ-UHFFFAOYSA-N

物化性质

• 沸点：
  205 °C(lit.)
• 密度：
  0.887 g/mL at 25 °C(lit.)
• 闪点：
  199 °F

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  12
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2909199090

SDS

Version 1.2
Regulation (EC) No 1907/2006

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1 - Product and Company Information

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Product Name 1,6-HEXANEDIOL DIVINYL ETHER, 97%

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2 - Hazards Identification

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3 - Composition/Information on Ingredients

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Product Name CAS # EC no Annex I
Index Number
1,6-HEXANEDIOL DIVINYL ETHER, 97% 19763-13-4 243-277-5 None
Formula C10H18O2
Molecular Weight 170,2500 AMU

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4 - First Aid Measures

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AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of contact, immediately wash skin with soap and copious
amounts of water.
AFTER EYE CONTACT
In case of contact, immediately flush eyes with copious amounts
of water for at least 15 minutes.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.

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5 - Fire Fighting Measures

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EXTINGUISHING MEDIA
Suitable: For small (incipient) fires, use media such as
"alcohol" foam, dry chemical, or carbon dioxide. For large
fires, apply water from as far as possible. Use very large
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quantities (flooding) of water applied as a mist or spray; solid
streams of water may be ineffective. Cool all affected
containers with flooding quantities of water.
SPECIAL RISKS
Specific Hazard(s): Combustible liquid. Emits toxic fumes under
fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.

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6 - Accidental Release Measures

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PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear respirator, chemical safety goggles, rubber boots, and
heavy rubber gloves.
METHODS FOR CLEANING UP
Absorb on sand or vermiculite and place in closed containers for
disposal. Ventilate area and wash spill site after material
pickup is complete.

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7 - Handling and Storage

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HANDLING
Directions for Safe Handling: Avoid inhalation. Avoid contact
with eyes, skin, and clothing. Avoid prolonged or repeated
exposure.
STORAGE
Conditions of Storage: Keep tightly closed. Keep away from heat
and open flame. Store in a cool dry place. Store under nitrogen.
Incompatible Materials: Avoid contact with acid.

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8 - Exposure Controls / Personal Protection

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ENGINEERING CONTROLS
Safety shower and eye bath. Mechanical exhaust required.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling. Wash contaminated clothing before
reuse.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Use respirators and components tested and
approved under appropriate government standards such as NIOSH (US)
or CEN (EU). Respiratory protection is not required. Where
protection is desired, use multi-purpose combination (US) or type
ABEK (EN 14387) respirator cartridges.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.

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9 - Physical and Chemical Properties

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pH N/A
BP/BP Range 205,000 °C 760,000 mmHg
MP/MP Range N/A
Flash Point 93,000 °C Method: closed cup
Flammability N/A
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Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density 0,8870 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A

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10 - Stability and Reactivity

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STABILITY
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: May occur

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11 - Toxicological Information

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SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Eye Contact: May cause eye irritation.
Multiple Routes: May be harmful by inhalation, ingestion, or
skin absorption.

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12 - Ecological Information

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No data available.

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13 - Disposal Considerations

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SUBSTANCE DISPOSAL
This combustible material may be burned in a chemical incinerator
equipped with an afterburner and scrubber. Observe all federal,
state, and local environmental regulations.

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14 - Transport Information

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RID/ADR
Non-hazardous for road transport.
IMDG
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Non-hazardous for sea transport.
IATA
Non-hazardous for air transport.

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15 - Regulatory Information

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COUNTRY SPECIFIC INFORMATION
Germany
WGK: 3
Self-Classification

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16 - Other Information

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WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2010 Co. License granted to make
unlimitedpaper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  1,6-己二醇二乙烯醚 在 1-甲基吡咯烷 、 lithium aluminium tetrahydride 、 二氯二茂锆 作用下， 以 2-甲基四氢呋喃 为溶剂， 反应 20.0h， 以67%的产率得到6-(乙烯基氧基)-1-己醇
  参考文献：
  名称：

  锆催化加氢金属化/β消除方法可还原性的CO，CN和CS裂解。

  摘要：

  据报道锆对Csp3和Csp2碳-杂原子键的催化还原裂解，利用链状烯烃官能团作为无痕导向基团。该反应已在CO，CN和CS键上成功证明，并建议通过原位形成的氢化锆催化剂的加氢锆/β-杂原子消除顺序进行。催化剂的位置异构化还能够裂解均烯丙基醚并除去末端的烯丙基和炔丙基。

  DOI：

  10.1021/acs.orglett.9b02572
• 作为产物：
  描述：

  乙酸乙烯酯 、 1,6-己二醇 在 bis(1,5-cyclooctadiene)diiridium(I) dichloride 、 sodium carbonate 作用下， 以 甲苯 为溶剂， 以68%的产率得到1,6-己二醇二乙烯醚
  参考文献：
  名称：

  锆催化加氢金属化/β消除方法可还原性的CO，CN和CS裂解。

  摘要：

  据报道锆对Csp3和Csp2碳-杂原子键的催化还原裂解，利用链状烯烃官能团作为无痕导向基团。该反应已在CO，CN和CS键上成功证明，并建议通过原位形成的氢化锆催化剂的加氢锆/β-杂原子消除顺序进行。催化剂的位置异构化还能够裂解均烯丙基醚并除去末端的烯丙基和炔丙基。

  DOI：

  10.1021/acs.orglett.9b02572

文献信息

• Copolymerizable methine and anthraquinone compounds and articles containing them
  申请人：Pearson Clay Jason

  公开号：US20060115516A1

  公开（公告）日：2006-06-01

  This invention relates to polymerizable ultraviolet light absorbers and yellow colorants and their use in ophthalmic lenses. In particular, this invention relates to polymerizable ultraviolet light absorbing methine compounds and yellow compounds of the methine and anthraquinone classes that block ultraviolet light and/or violet-blue light transmission through ophthalmic lenses.

  这项发明涉及可聚合的紫外光吸收剂和黄色染料，以及它们在眼镜镜片中的应用。具体而言，这项发明涉及可聚合的紫外光吸收亚甲基化合物和亚甲基和蒽醌类化合物，这些化合物通过眼镜镜片阻挡紫外光和/或紫蓝光的透射。
• Copolymerizable azo compounds and articles containing them
  申请人：Pearson Clay Jason

  公开号：US20060110430A1

  公开（公告）日：2006-05-25

  Polymerizable light absorbing azo dyes are disclosed useful as monomers in the formation of devices such as, but not limited to ocular lenses. Specifically, intraocular lenses (IOL) are disclosed wherein one or more of the light absorbing dye is covalently bonded to other structural polymers though ethylene unsaturated groups. The resulting IOLs possess light absorbing properties without significant amounts of free (un-bound) azo dye molecules present in the final structural polymer matrix.

  可聚合的吸光偶氮染料被披露为在形成设备时作为单体有用，这些设备包括但不限于眼镜片。具体地，披露了一种人工晶状体（IOL），其中一个或多个吸光染料通过乙烯不饱和基与其他结构聚合物共价结合。由此产生的IOL具有吸光性能，而最终结构聚合物基质中几乎没有自由（未结合）偶氮染料分子。
• Palladium-Catalyzed Dimerization of Vinyl Ethers to Acetals
  作者：Changle Chen、Richard F. Jordan

  DOI：10.1021/ja104523y

  日期：2010.8.4

  and silyl vinyl ethers to beta,gamma-unsaturated CH(2)=CHCH(2)CH(OR)(2) acetals, and they cyclize divinyl ethers to analogous cyclic acetals. A plausible mechanism comprises in situ generation of an active PdOR alkoxide species, double vinyl ether insertion to generate PdCH(2)CH(OR)CH(2)CH(OR)(2)} species, and beta-OR elimination to generate the acetal product. In the presence of vinyl ethers, (alpha-diimine)PdCl(+)

  (α-二亚胺)PdCl(+) 物质将烷基和甲硅烷基乙烯基醚催化二聚化为 β,γ-不饱和 CH(2)=CHCH(2)CH(OR)(2) 缩醛，并将二乙烯基醚环化为类似的环状缩醛. 一种可能的机制包括原位生成活性 PdOR 醇盐物质，双乙烯基醚插入生成 PdCH(2)CH(OR)CH(2)CH(OR)(2)} 物质，以及β-OR 消除以生成 PdCH(2)CH(OR)CH(2)CH(OR)(2)} 物质生成缩醛产物。在乙烯基醚的存在下，(α-二亚胺)PdCl(+) 物质可用于引发乙烯聚合。
• Development of a Highly Efficient Catalytic Method for Synthesis of Vinyl Ethers
  作者：Yoshio Okimoto、Satoshi Sakaguchi、Yasutaka Ishii

  DOI：10.1021/ja0173932

  日期：2002.2.1

  A new method for the preparation of alkyl vinyl ethers has been developed. Thus, various types of alkyl vinyl ethers were synthesized by the reaction of alcohols with vinyl acetate under the influence of a catalytic amount of [Ir(cod)Cl]2 combined with Na2CO3 in good to excellent yields.

  开发了一种制备烷基乙烯基醚的新方法。因此，在催化量的 [Ir(cod)Cl]2 与 Na2CO3 结合的影响下，通过醇与乙酸乙烯酯的反应合成了各种类型的烷基乙烯基醚，收率良好至极好。
• ビニルエーテルの製造方法、及びエーテル交換反応用触媒
  申请人：学校法人 関西大学

  公开号：JP2016169211A

  公开（公告）日：2016-09-23

  【課題】少ない触媒量であっても反応が十分に進行し、又、当該触媒の回収及び再利用が行いやすく操作性に優れるビニルエーテルの製造方法の提供。【解決手段】アルコールと、式（２）で表されるビニルエーテルとを、エーテル交換反応させる、式（３）で表されるビニルエーテルの製造方法。配位性有機溶媒を含む溶媒中で遷移金属化合物を加熱することにより得られる金属ナノクラスターと含窒素複素環化合物からなる触媒。【選択図】なし

  提供一种制备乙烯醚的方法，即使使用少量催化剂，反应也能充分进行，同时催化剂的回收和再利用容易且具有良好的操作性。将醇和由式（2）表示的乙烯醚进行醚交换反应，制备乙烯醚的方法，其中通过在含有配位性有机溶剂的溶剂中加热过渡金属化合物得到的金属纳米团簇和含氮复环化合物组成的催化剂。