波森 | 56222-03-8

• 物质功能分类: 天然产物 - 酚类
• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二芳基庚烷
• 中文名称: 波森
• 英文名称: porson
• 英文别名: Porson；3,8-dihydroxy-15,16,17-trimethoxytricyclo[12.3.1.12,6]nonadeca-1(17),2,4,6(19),14(18),15-hexaen-9-one
• CAS: 56222-03-8
• 化学式: C₂₂H₂₆O₆
• 分子量: 386.445
• InChiKey: IFQDEGDKLBEYHN-UHFFFAOYSA-N

物化性质

• 沸点：
  618.7±55.0 °C(Predicted)
• 密度：
  1.212±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  28
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.41
• 拓扑面积：
  85.2
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  波森 在 sodium tetrahydroborate 作用下， 以 甲醇 为溶剂， 反应 2.0h， 以3 mg的产率得到15,16,17-Trimethoxy-tricyclo[12.3.1.1^2,6]nonadeca-1(18),2(19),3,5,14,16-hexaene-3,8,9-triol
  参考文献：
  名称：

  Diarylheptanoids from Myrica gale var. tomentosa and Revised Structure of Porson.

  摘要：

  From the stems of Myrica gale var. tomentosa (Myricaceae), two new diarylhyptanoids (3 and 4) were isolated together with myricanone, porson, gallic acid and myricetin 3-O-(6"-galloyl)-β-D-galactopyranoside. On the basis of spectroscopic and chemical evidence, the structures of 3 and 4 have been determined as 12-dehydroporson and 12-hydroxymyricanone, respectively. The structure of porson was reinvestigated, and a revised structure, 12-hydroxy-5-O-methylmyricanone, was proposed.

  DOI：

  10.1248/cpb.43.1674

文献信息

• Diarylheptanoids from Myrica gale var. tomentosa and Revised Structure of Porson.
  作者：Masahiro NAGAI、Junko DOHI、Motohiko MORIHARA、Nobuko SAKURAI

  DOI：10.1248/cpb.43.1674

  日期：——

  From the stems of Myrica gale var. tomentosa (Myricaceae), two new diarylhyptanoids (3 and 4) were isolated together with myricanone, porson, gallic acid and myricetin 3-O-(6"-galloyl)-β-D-galactopyranoside. On the basis of spectroscopic and chemical evidence, the structures of 3 and 4 have been determined as 12-dehydroporson and 12-hydroxymyricanone, respectively. The structure of porson was reinvestigated, and a revised structure, 12-hydroxy-5-O-methylmyricanone, was proposed.