10-Methoxy-6,10-dimethyl-2-undecanone | 61099-40-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 10-Methoxy-6,10-dimethyl-2-undecanone
• 英文别名: (E)-10-methoxy-6,10-dimethylundecan-2-one；10-Methoxy-6,10-dimethylundecan-2-on；10-methoxy-6,10-dimethyl-undecan-2-one；10-Methoxy-6,10-dimethylundecan-2-one
• CAS: 61099-40-9
• 化学式: C₁₄H₂₈O₂
• 分子量: 228.375
• InChiKey: CZKHFSCCPRLTCE-UHFFFAOYSA-N

物化性质

• 沸点：
  306.6±25.0 °C(Predicted)
• 密度：
  0.866±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  16
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  10-Methoxy-6,10-dimethyl-2-undecanone 在 sodium tetrahydroborate 作用下， 以 乙醇 为溶剂， 生成 10-Methoxy-6,10-dimethyl-2-undecanol
  参考文献：
  名称：

  McQuillin,F.J.; Wood,M., Journal of the Chemical Society. Perkin transactions I, 1976, p. 1762 - 1768

  摘要：

  DOI：
• 作为产物：
  描述：

  (E)-ψ-紫罗兰酮 在 镍 sodium tetrahydroborate 、 jones reagent 、 mercury(II) diacetate 、 氢气 作用下， 以 甲醇 、 丙酮 为溶剂， 反应 15.0h， 生成 10-Methoxy-6,10-dimethyl-2-undecanone
  参考文献：
  名称：

  Szykula, Jerzy; Zabza, Andrzej, Liebigs Annalen der Chemie, 1987, p. 709 - 710

  摘要：

  DOI：

文献信息

• (BDP)CuH:  A “Hot” Stryker's Reagent for Use in Achiral Conjugate Reductions
  作者：Benjamin A. Baker、Žarko V. Bošković、Bruce H. Lipshutz

  DOI：10.1021/ol702689v

  日期：2008.1.1

  A ligand-modified, economical version of Stryker's reagent (SR) has been developed based on a bidentate, achiral bis-phosphine. Generated in situ, "(BDP)CuH" smoothly effects conjugate reductions of a variety of unsaturated substrates, including those that are normally unreactive toward SR. Substrate-to-ligand ratios typically on the order of 1000-10000:1 can be used leading to products in high yields

  基于二齿非手性双膦，开发了配体修饰的经济型Stryker试剂（SR）。原位生成的“（BDP）CuH”可平滑地实现多种不饱和底物的共轭还原，包括那些通常对SR不反应的底物。可以使用通常在1000-10000：1量级的底物与配体的比率，以产生高产率的产物。
• Structure–activity relationship of novel juvenile hormone, JHSB3, isolated from the stink bug, Plautia stali
  作者：Kanako Kaihara、Toyomi Kotaki、Hideharu Numata、Yasufumi Ohfune、Tetsuro Shinada

  DOI：10.1016/j.tet.2011.10.080

  日期：2012.1

  The structure-activity relationship of JHSB(3) isolated from the pentatomid bug. Plautia stali, was studied. Various synthetic analogs were synthesized and subjected to the juvenilizing activity tests using the last instar nymphs of P. stali. These studies indicated that the coexistence of the ester carbonyl group, two epoxides at C2,3 and C10,11 were proved to be crucial for the potent juvenilizing activity. Among the tested analogs, we found highly potent analogs in which the C6,7 double bond of JHSB3 was saturated (0.1 mu g/insect). The methoxy analogs in which the epoxide moiety at C10,11 was substituted with a methoxy group exerted a moderate juvenilizing activity. (C) 2011 Elsevier Ltd. All rights reserved.
• SZYKULA J.; ZABZA A., LIEBIGS ANN. CHEM.,(1987) N 8, 709-710
  作者：SZYKULA J.、 ZABZA A.

  DOI：——

  日期：——