2-methoxythymol | 104236-57-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 2-methoxythymol
• 英文别名: Methyl-(6-hydroxy-2-methyl-5-isopropyl-phenyl)-aether；6-Isopropyl-2-methoxy-3-methyl-phenol；3-Hydroxy-2-methoxy-p-cymol；2-Methoxy-3-methyl-6-propan-2-ylphenol
• CAS: 104236-57-9
• 化学式: C₁₁H₁₆O₂
• 分子量: 180.247
• InChiKey: WJTDUKBUTCPOOA-UHFFFAOYSA-N

物化性质

• 熔点：
  45-47 °C
• 沸点：
  116-118 °C(Press: 12 Torr)
• 密度：
  1.011±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-methoxythymol 、 硫酸二甲酯 以0.108 g的产率得到2,3-dimethoxy-p-cymene
  参考文献：
  名称：

  Wahidullah, Solimabi; Paknikar, S. K., Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1987, vol. 26, # 1-12, p. 880 - 881

  摘要：

  DOI：
• 作为产物：
  描述：

  diosphenol methyl ether 在 selenium 作用下， 反应 2.0h， 以1.896 g的产率得到2-methoxythymol
  参考文献：
  名称：

  Wahidullah, Solimabi; Paknikar, S. K., Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1987, vol. 26, # 1-12, p. 880 - 881

  摘要：

  DOI：

文献信息

• Topical formulations and methods of use
  申请人：Morariu Marius

  公开号：US20060216251A1

  公开（公告）日：2006-09-28

  A topical composition comprising a lipoic acid, a carnitine, and a carnosine in a suitable vehicle for topical application and a method for treating skin is provided. The present compositions are useful in improving the appearance of aged skin characterized by wrinkles and loss of elasticity. Preferred components include R-lipoic acid or R-dihydrolipoic acid, acetyl-1-carnitine, and 1-carnosine.

  本发明提供了一种外用组合物，该组合物包含硫辛酸、肉毒碱和肉毒碱，并以适合外用的载体形式存在，还提供了一种治疗皮肤的方法。本组合物有助于改善以皱纹和失去弹性为特征的老化皮肤的外观。优选成分包括 R-硫辛酸或 R-二氢硫辛酸、乙酰基-1-肉碱和 1-肉碱。
• Straneo, Gazzetta Chimica Italiana, 1940, vol. 70, p. 27
  作者：Straneo

  DOI：——

  日期：——
• WAHIDULLAH, SOLIMABI;PAKNIKAR, S. K., INDIAN J. CHEM., 26,(1987) N 9, 880-881
  作者：WAHIDULLAH, SOLIMABI、PAKNIKAR, S. K.

  DOI：——

  日期：——
• Methods of Treating Skin
  申请人：Morariu Marius

  公开号：US20100272790A1

  公开（公告）日：2010-10-28

  A topical composition comprising a lipoic acid, a carnitine, and a carnosine in a suitable vehicle for topical application and a method for treating skin is provided. The present compositions are useful in improving the appearance of aged skin characterized by wrinkles and loss of elasticity. Preferred components include R-lipoic acid or R-dihydrolipoic acid, acetyl-l-carnitine, and l-carnosine.
• METHODS OF TREATING SKIN
  申请人：Tracie Martyn International, Inc.

  公开号：US20140155961A1

  公开（公告）日：2014-06-05

  A topical composition comprising a lipoic acid, a carnitine, and a carnosine in a suitable vehicle for topical application and a method for treating skin is provided. The present compositions are useful in improving the appearance of aged skin characterized by wrinkles and loss of elasticity. Preferred components include R-lipoic acid or R-dihydrolipoic acid, acetyl-l-carnitine, and l-carnosine.