2-乙基己酸镁盐 | 15602-15-0

• 物质功能分类: 有机原料 - 羧酸类化合物及衍生物
• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 2-乙基己酸镁盐
• 中文别名: 2-乙基己酸镁
• CAS: 15602-15-0
• 化学式: C8H16MgO2
• 分子量: 168.52
• InChiKey: VUQZRJSZSGLANF-UHFFFAOYSA-N

物化性质

• 闪点：
  4°C

计算性质

• 辛醇/水分配系数(LogP)：
  1.91
• 重原子数：
  11
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] PROCESSES FOR THE PREPARATION OF UNSATURATED ESTERS<br/>[FR] PROCÉDÉS DE PRÉPARATION D'ESTERS INSATURÉS
  申请人：AROMOR FLAVORS & FRAGRANCES LTD

  公开号：WO2015059696A1

  公开（公告）日：2015-04-30

  The invention provides a process for the preparation of alkyl 4-methyl-6-(2,6,6-trimethylcyclohex-lenyl) hex-3-enoate comprising a single step wherein 2-methyl-4-(2,6,6- trimethylcyclohex-l-en-l-yl)butanal is reacted with monoalkyl malonate.

  该发明提供了一种制备烷基4-甲基-6-(2,6,6-三甲基环己烯基)己-3-烯酸酯的方法，包括一步反应，其中2-甲基-4-(2,6,6-三甲基环己-1-烯-1-基)丁醛与单烷基丙二酸酯发生反应。
• Process for solvent removal from omeprazole salts
  申请人：LEK Pharmaceuticals d.d.

  公开号：EP1947099A1

  公开（公告）日：2008-07-23

  The present invention relates to a process for removing an organic solvent from a salt of omeprazole, in particular a magnesium salt of omeprazole, a composition comprising a salt of omeprazole, in particular a magnesium salt of omeprazole obtainable by such a process, and pharmaceutical compositions comprising said composition or a salt of omeprazole, in particular a magnesium salt of omeprazole, in particular where omeprazole is S-omeprazole..

  本发明涉及一种从奥美拉唑的盐中去除有机溶剂的方法，特别是从奥美拉唑的镁盐中去除有机溶剂的方法，包括一种奥美拉唑的盐，特别是通过这种方法获得的奥美拉唑的镁盐，以及包含所述组合物或奥美拉唑的盐的药物组合物，特别是奥美拉唑为S-奥美拉唑。
• S-omeprazole magnesium
  申请人：Savanovic Vranicar Lidija

  公开号：US20070149573A1

  公开（公告）日：2007-06-28

  The present invention discloses a process for preparing a magnesium salt of S-omeprazole. The S-omeprazole salt preferably has a water content below about 4.8% by weight, a magnesium content of about 3.4-4.0% by weight, calculated on the weight of anhydrous, solvent free S-omeprazole magnesium, and has an optical purity of at least about 85% entantiomeric excess (“e.e.”). In addition, the present invention provides a magnesium salt of S-omeprazole which is substantially free of neutral omeprazole, meaning that the product contains less than about 3% by weight of a-sum of neutral S-omeprazole and neutral omeprazole. Moreover, the S-omeprazole magnesium according to the invention preferably has assay of related substances and degradation products of less than about 0.1 % by weight as determined by high performance liquid chromatography (HPLC).

  本发明揭示了一种制备S-奥美拉唑镁盐的过程。S-奥美拉唑盐的水含量最好低于约4.8%的重量，镁含量约为3.4-4.0%的重量，以无水、无溶剂的S-奥美拉唑镁为基础计算，其光学纯度至少为约85%的对映体过量（“e.e.”）。此外，本发明提供了一种S-奥美拉唑镁盐，该盐基本上不含中性奥美拉唑，也就是产品中少于约3%的重量是中性S-奥美拉唑和中性奥美拉唑的总和。此外，根据本发明，S-奥美拉唑镁最好具有相关物质和降解产物的测定值小于约0.1%的重量，由高效液相色谱法（HPLC）确定。
• PROCESS FOR THE PREPARATION OF ESOMEPRAZOLE MAGNESIUM IN A STABLE FORM
  申请人：Toplak Casar Renata

  公开号：US20100016370A1

  公开（公告）日：2010-01-21

  There is provided a process for preparing purified esomeprazole magnesium, comprising the steps of: providing esomeprazole magnesium; contacting said esomeprazole magnesium with a non-solvent comprising an aqueous component up to a maximum content defined by water saturation in the non-solvent; and recovering purified esomeprazole magnesium formed from the contacting step. The process is particularly suitable to obtain esomeprazole magnesium dihydrate, especially form A. The esomeprazole magnesium obtained is remarkably pure, stable and is resistant to form interchangeability.

  提供了一种制备纯化埃索美拉唑镁的方法，包括以下步骤：提供埃索美拉唑镁；将所述埃索美拉唑镁与一种非溶剂接触，所述非溶剂包括最大含水量，由非溶剂中的水饱和度定义；并从接触步骤中回收形成的纯化埃索美拉唑镁。该方法特别适用于获得二水合埃索美拉唑镁，尤其是A型。所获得的埃索美拉唑镁非常纯净、稳定且耐形态可互换。
• [EN] PROCESSES AND COMPOSITIONS FOR TOLUENE METHYLATION IN AN AROMATICS COMPLEX<br/>[FR] PROCÉDÉS ET COMPOSITIONS POUR LA MÉTHYLATION DU TOLUÈNE DANS UN COMPLEXE D'HYDROCARBURES AROMATIQUES
  申请人：UOP LLC

  公开号：WO2017091350A1

  公开（公告）日：2017-06-01

  This present disclosure relates to processes and compositions for toluene methylation in an aromatics complex for producing paraxylene. More specifically, the present disclosure relates to a process for producing paraxylene which includes alkylating a toluene stream and a methanol stream in a toluene methylation zone operating under toluene methylation conditions in the presence of a catalyst comprising a MFI crystal to produce a toluene methylation product stream.

  本公开涉及在芳烃复合物中进行甲苯甲基化的工艺和组合物，以生产对二甲苯。更具体地，本公开涉及一种生产对二甲苯的工艺，其中在存在MFI晶体催化剂的情况下，在甲苯甲基化条件下，通过在甲苯流和甲醇流中进行烷基化来产生甲苯甲基化产物流。